The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapyPerspective Published on 2020-05-132022-10-28 Journal: Bone marrow transplantation [Category] COVID-19, MERS, SARS, [키워드] age Allogeneic autologous Cancer candidate CAR Care Cell cell transplantation cellular condition COVID-19 COVID-19 pandemic Diseases Donor donors European Factor HCT Health Health care include Infectious disease management Marrow new coronavirus SARS-CoV-2 pandemic Patient patients physician recipient recipients recommendation severe disease Society Spread Stress T cells T-cell the disease therapy transplantation WHO working [DOI] 10.1038/s41409-020-0919-0 PMC 바로가기 [Article Type] Perspective
Confronting Covid-19 by exploring the possibility of vaccinating with live SARS-CoV-2 virus itself, via a route that would reduce the incidence of pulmonary complications폐 합병증 발병률을 줄이는 경로를 통해 살아있는 SARS-CoV-2 바이러스 자체의 예방 접종 가능성을 탐색하여 Covid-19에 맞서기Opinion Article Published on 2020-04-292022-09-11 Journal: F1000Research [Category] MERS, SARS, 비임상, [키워드] Aerosols airway animal model animal models breath bypassing can be used cats cellular clinical trial components conducted Contagiosity Course digestive digestive tract Effectiveness experiment ferret ferrets hamsters help Hope immune responses Immune status incidence infections inoculation intra-peritoneal lead leads less live SARS-CoV-2 Lungs macaques matter priority profiles pulmonary complication pulmonary complications Pulmonary pathology recipient recipients reduce reduced released resulting risk route SARS-CoV-2 SARS-CoV-2 virus serological Skin test step subjects tested the SARS-CoV-2 virus vaccination vector Viral viral replication virus Volunteer [DOI] 10.12688/f1000research.23480.1 PMC 바로가기 [Article Type] Opinion Article
Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV: a randomised controlled trialHIV에 감염된 임산부에서 3가 비활성화 인플루엔자 백신의 다양한 투여 일정의 면역원성과 안전성: 무작위 대조 시험Article Published on 2020-01-032022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] age All participants analysed Antenatal Antibody Response assigned Birth clinics completion computer-generated Controlled trial dose dosing schedule double-blind eligible ENhance enrolled enrolment estimated gestational age except for Final finding foundation Frequency funding gestational age greater group Group allocation HIV immunogenic immunogenicity Immunogenicity analyses Immunogenicity analysis inactivated induce Infant Infants Influenza influenza vaccine Local Melinda Gate Melinda Gates mother Neonates Newborn newborn infants outcome participant pregnant women protective antibodies Protective antibody randomisation list randomised randomised controlled trial Randomly reaction receive recipient recipients recruited regimen Registered Safety Seasonal influenza seroconversion rate seroconversion rates Seven significantly higher single dose Single-dose South Africa Standard-dose strain Strains systemic reactions the vaccine three groups transfer trivalent Vaccine vaccine dose were measured with HIV women [DOI] 10.1016/S2352-3018(19)30322-4 PMC 바로가기 [Article Type] Article
Use of whole-genome sequencing in the molecular investigation of care-associated HCoV-OC43 infections in a hematopoietic stem cell transplant unitArticle Published on 2019-11-162022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, MERS, [키워드] Amino acid analysed Asian Care-associated infections Cell characterized circulating Cluster collected defined European Genotype HCoV-OC43 Hematopoietic cell transplant hospital HSCT HSCT patient Human coronavirus identify identity implicated Infection infections investigated involved isolate molecular nasal swab Next-generation sequencing objective Patient patients Phylogenetic phylogenetic analyses Phylogenetic tree recipients respiratory viral infection Result S gene sequence Stem cell transplantation strain Substitution the S protein Transmission were used while Whole genome sequencing whole-genome sequencing [DOI] 10.1016/j.jcv.2019.104206 PMC 바로가기 [Article Type] Article
Antibody Kinetics and Response to Routine Vaccinations in Infants Born to Women Who Received an Investigational Trivalent Group B Streptococcus Polysaccharide CRM 197 -Conjugate Vaccine During Pregnancy조사 3가 그룹 B 연쇄상구균 다당류 CRM 197 -임신 중 접합 백신을 받은 여성에게서 태어난 영아의 항체 동역학 및 정기 예방 접종에 대한 반응Articles and Commentaries Published on 2017-12-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, [키워드] age antenatal vaccination antibody antibody level antibody levels Birth capsular clinical clinically Combination detectable Diphtheria diphtheria toxoid disease dosage dosages dose during pregnancy elicited enrolled geometric mean geometric mean concentration group group B Streptococcus conjugate vaccine groups Haemophilus influenzae Haemophilus influenzae type b immune response immune responses Infant Infants invasive investigated Kinetics Maternal mother not affect pediatric Placebo placebo group pneumococcal pneumococcal vaccination Pregnancy Randomized receive Received recipients Registration response Result routine routine immunization serotype serotype-specific serotypes significantly higher single-center study Streptococcus Tetanus the placebo group timepoint transferred trivalent vaccination Vaccine were assessed women [DOI] 10.1093/cid/cix666 PMC 바로가기 [Article Type] Articles and Commentaries
Pre- and post-transfusion testing for hepatitis B virus surface antigen and antibody in blood recipients: a single-institution experience in an area of high endemicityArticle Published on 2012-01-012023-06-08 Journal: Annals of laboratory medicine [Category] B형 간염, [키워드] Hepatitis B virus recipients Test transfusion Transmission. [DOI] 10.3343/alm.2012.32.1.73 PMC 바로가기
A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virusClinical Trial Published on 2010-05-112022-10-06 Journal: Proceedings of the National Academy of Sciences of [Category] 진단, [키워드] acquisition Administered Adult Adults Analysis antibody antiviral activity Antiviral effect assays clinical evidence concentrations decrease different double-blind Effectiveness enrolled exhibiting Factors healthy subject Human increase in independent Infected infected children Infection intranasal mechanism mRNA multiple logistic regression murine model nasal nasal washe nucleocapsid number of infected PCR Placebo placebo-controlled study placebo-controlled trial Proinflammatory cytokine proportion Protein protein expression Randomized recipient recipients representing respiratory syncytial virus RNA RSV RSV infection safety profile saline placebo significantly lower siRNA subjects tested therapeutic Therapeutic approach therapy treat uninfected unique viral culture was measured wild-type [DOI] 10.1073/pnas.0912186107 PMC 바로가기 [Article Type] Clinical Trial
Monoclonal antibodies versus reverse transcription‐PCR for detection of respiratory viruses in a patient population with respiratory tract infections admitted to hospitalResearch Article Published on 2004-12-152022-11-01 Journal: Journal of medical virology [Category] Coronavirus, [키워드] added addition Adults another respiratory virus antibody approach assays association Bronchoalveolar lavage bronchoalveolar lavage sample caused circulating Coinfection Combination coronavirus detected Diagnosis diagnostic examined group H1N1 H3N2 HCoV hospital Human coronavirus human metapneumovirus human parainfluenza virus Human respiratory syncytial virus immunological Inc infected children infecting Infection infections influenza virus investigated less Lower respiratory tract lung transplant majority métapneumovirus molecular Molecular assay monoclonal antibody nasopharyngeal Patient patient population patients peaked pediatric positive proportion recipients respiratory coinfections respiratory infections respiratory syncytial virus respiratory tract infection respiratory viral respiratory virus respiratory virus reverse transcription RT‐PCR RT‐PCR searched Strains tested virus virus were infected [DOI] 10.1002/jmv.20276 PMC 바로가기 [Article Type] Research Article