Diagnostic accuracy of a rapid diagnostic test for the early detection of COVID-19코로나19 조기진단을 위한 신속진단검사의 진단 정확도Article Published on 2022-02-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Abbott Accuracy Antigen Asymptomatic individuals average benefit Card Chicago Cohort coronavirus COVID-19 COVID-19 infection COVID-19 testing Critical Ct values diagnostic Diagnostic accuracy evaluate evaluated evidenced False negative N gene nasal swab nostril pandemic PCR test PCR testing Rapid Rapid diagnostic test Rapid test rapid testing reference standard reported RT-PCR SARS-CoV-2 pandemic sensitivity specificity standard reference Surveillance Swab symptomatic symptomatic and asymptomatic tested the SARS-CoV-2 university USA was tested [DOI] 10.1016/j.jcv.2021.105023 PMC 바로가기 [Article Type] Article
A quantitative assay for detection of SARS-CoV-2 neutralizing antibodiesSARS-CoV-2 중화 항체 검출을 위한 정량 분석Article Published on 2022-02-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] 95% CI Alpha analyzed antibody Chorus Concordance COVID-19 Critical cross reaction diagnosis of COVID-19 diagnostic assay evaluate evaluated False negative False positives human serum IgA IgG IgM immunoassay Infection neutralization Neutralizing Neutralizing antibodies neutralizing antibody no significant differences other respiratory infection other respiratory infections patients positive Post-infection quantitative assay quantitative determination respiratory respiratory infections SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 virus sensitivity Sensitivity and specificity sera serological assays significant difference significant differences specific antibodies specific antibody specificity subjects symptomatic tracer Trio uninfected vaccination value variants virus were used [DOI] 10.1016/j.jcv.2021.105064 PMC 바로가기 [Article Type] Article
Prevention of host-to-host transmission by SARS-CoV-2 vaccinesSARS-CoV-2 백신에 의한 숙주 간 전파 방지Review Published on 2022-02-012022-09-12 Journal: The Lancet. Infectious Diseases [Category] Fulltext, MERS, 진단, [키워드] approved available data clinical trial Course distribution droplets Effect immunological individual individuals Infection infection with SARS-CoV-2 intramuscular less limit mechanisms mucosa observational study Particle population-level effect prevention Primary infection Randomised trial reduce reducing Replication respiratory epithelia SARS-CoV-2 SARS-CoV-2 vaccine shown symptomatic the vaccine titre Transmissibility Transmission Vaccine viral replication [DOI] 10.1016/S1473-3099(21)00472-2 PMC 바로가기 [Article Type] Review
Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trialCOVID-19(DisCoVeRy)로 입원한 환자의 치료를 위한 렘데시비르 + 표준 치료 대 표준 치료 단독: 3상, 무작위, 대조, 공개 시험Clinical Trial Published on 2022-02-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] Fulltext, MERS, 임상, 치료법, 치료제, [키워드] Abstract activities activity acute respiratory distress acute respiratory distress syndrome adaptive Administered Adult patient Adult patients Analysis antiviral efficacy assigned Bacterial infection Belgium block Breastfeeding Chronic kidney disease clinical clinical benefit Clinical efficacy clinical evidence Clinical research clinical status Combination Commission computer-generated conducted control group Controlled trial COVID-19 criteria death development discharged distribution elevated elevated liver enzymes eligible enrolled Europe European evaluate evidence of exclusion criteria extracorporeal membrane oxygenation followed by France French group Health care hepatorenal syndrome high flow oxygen devices hospital hospitalised Hydroxychloroquine Inclusion indication Innovation intention-to-treat population interferon interferon beta Interferon beta-1a intravenous intravenous infusion Invasive mechanical ventilation investigators Kidney disease laboratory-confirmed SARS-CoV-2 infection limitation liver enzymes Lopinavir Lopinavir-ritonavir Luxembourg material Ministry of Health modified intention-to-treat multicentre no significant difference non-invasive ventilation not significant Occurrence Odds ratio once daily one health Open-label Ordinal Scale oxygen oxygen supplementation oxygen support participant Patient Phase 3 Pneumonia Portugal Pregnancy Primary outcome random assignment randomisation randomised Randomly receive Regional Registered Remdesivir required requiring supplemental oxygen respiratory distress ribavirin Ritonavir Safety SARS-CoV-2 SARS-COV-2 infection Secondary outcomes Serious Adverse Event Serious Adverse Events seven-point ordinal scale Severity of disease Sponsor Standard of care stratified supplemental oxygen Support symptomatic syndrome the WHO translation Treatment treatment group treatment groups Trial Tumor union ventilator were excluded WHO ordinal scale with COVID-19 [DOI] 10.1016/S1473-3099(21)00485-0 PMC 바로가기 [Article Type] Clinical Trial
Obstetric and neonatal outcomes after SARS-CoV-2 infection in the first trimester of pregnancy: A prospective comparative study임신 1분기 SARS-CoV-2 감염 후 산과 및 신생아 결과: 전향적 비교 연구Observational Study Published on 2022-02-012022-09-11 Journal: The journal of obstetrics and gynaecology research [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] abortion acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission adverse event antibody Antibody titer APGAR score Asymptomatic Birth Blood Cohort cohort study Composite Cord blood coronavirus coronavirus disease Coronavirus disease-19 COVID-19 defined evaluate events excluded first trimester growth higher risk hospital Hospital admission IgG antibodies Infection intensive care intrauterine growth restriction Maternal membranes Nasopharyngeal swab Neonatal Newborn Obstetric outcome Patient patients Pneumonia positive preeclampsia Pregnancy preterm delivery Primary outcome prospective observational cohort rupture SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significantly more Stillbirth Symptom symptomatic tested Transmission vertical transmission was performed were recorded women [DOI] 10.1111/jog.15105 PMC 바로가기 [Article Type] Observational Study
Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative reviewSARS-CoV-2 및 우려 변종에 대한 특성, 효능 및 효과에 대한 COVID-19 백신 비교: 서술적 검토Review Published on 2022-02-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse effects adverse event adverse events agency Alpha Analysis anaphylaxis AZD1222 benefit Beta bioRxiv BNT162b2 booster dose Characteristics Comparative analysis CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines Critical death Delta Delta variants dose doses effective Effectiveness Efficacy Evidence Gamma Google Scholar Heterologous highest Hospitalization Immunity immunization Infection mass vaccination medRxiv mRNA mRNA vaccine mRNA vaccines mRNA-1273 myocarditis pandemic Phase III trials Prevent reduced reference Regulatory review Safe SARS-CoV-2 SARS-COV-2 infection seroneutralization severe acute respiratory syndrome Coronavirus severe COVID-19 Severe infection severe infections symptomatic symptomatic case symptomatic cases symptomatic COVID-19 the vaccine vaccination Vaccine Vaccines variant variants variants of concern waning immunity website [DOI] 10.1016/j.cmi.2021.10.005 PMC 바로가기 [Article Type] Review
Hemodialysis patients with coronavirus disease 2019: reduced antibody response2019년 코로나바이러스 질환 혈액투석 환자: 항체 반응 감소Article Published on 2022-02-012022-09-11 Journal: Clinical and experimental nephrology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibody antibody production Antibody Response Antibody testing balance coronavirus coronavirus disease Coronavirus disease 2019 covariate COVID-19 COVID-19 patient detect disease distribution Hemodialysis higher risk hospitalized patient hospitalized patients iFlash IgG antibodies IgG antibody immune response Immunoglobulin increased risk Maintenance hemodialysis non-severe patients Pathogens Patient patients patients with COVID-19 performed produced Propensity score propensity score matching quantified reduced respiratory retrospective cohort study S1 subunit SARS-CoV-2 severe coronavirus disease severe COVID-19 severe disease Shenzhen significantly lower Spike protein symptom onset symptomatic symptomatic COVID-19 the disease the median the S1 subunit the spike protein was performed was used [DOI] 10.1007/s10157-021-02130-8 PMC 바로가기 [Article Type] Article
Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Development of Symptomatic COVID-19 in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial초기 무증상 SARS-CoV-2 감염에서 증상이 있는 COVID-19 발병에 대한 피하 카시리비맙 및 임데비맙 항체 조합 대 위약의 효과: 무작위 임상 시험Clinical Trial Published on 2022-02-012022-09-12 Journal: JAMA [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 1:1 age anti-SARS-CoV-2 antibody combination Asymptomatic asymptomatic infection baseline Casirivimab clinical Combination Contact COVID-19 development dose double-blind Effect Efficacy efficacy analysis efficacy end point eligible enrolled evaluate the effect event Follow-up household contact Imdevimab incidence index case individual Odds ratio outcome participant phase 3 trial Placebo placebo-controlled polymerase chain positive Positive test Prevent prevented primary end point progression proportion Randomized receive receiving reduce reduced reduction in reported Result risk Romania RT-qPCR SARS-CoV-2 SARS-COV-2 infection seronegative seronegative participant significantly Subcutaneous symptom duration symptomatic symptomatic disease symptomatic participant symptomatic SARS-CoV-2 infection Treatment treatment-emergent adverse event Viral load women [DOI] 10.1001/jama.2021.24939 PMC 바로가기 [Article Type] Clinical Trial
An observational study for appraisal of clinical outcome and risk of mother-to-child SARS-CoV-2 transmission in neonates provided the benefits of mothers’ own milkObservational Study Published on 2022-02-012022-10-05 Journal: European journal of pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age approach Asymptomatic benefit Breastfeeding clinical Clinical outcome collected COVID-19 demonstrated discharged distress enrolled fetal Follow-up hospital incidence India Infant Infection intensive care majority morbidity Mortality mother Mother-to-child transmission Nasopharyngeal swab nasopharyngeal swab sample Neonatal Neonate Neonates outcome positive positive RT-PCR Precaution protocols provided recorded risk Rooming-in RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission STABLE suffered Support Swab symptomatic tested Transmission upper respiratory viral persistence virus transmission World Health Organization [DOI] 10.1007/s00431-021-04206-9 PMC 바로가기 [Article Type] Observational Study
Immune response pattern across the asymptomatic, symptomatic and convalescent periods of COVID-19COVID-19의 무증상, 증상 및 회복기에 걸친 면역 반응 패턴Article Published on 2022-02-012022-09-11 Journal: Biochimica et biophysica acta. Proteins and proteo [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] activated addition Analysis Asymptomatic asymptomatic infection causative agent cholesterol cholesterol metabolism clinical measurement clinical measurements complex convalescent COVID-19 COVID-19 infection Diagnosis disease disorder disorders dysregulated dysregulation identify immune defect immune defects immune response Immunopathogenesis Intervention mass mass spectrometry metabolism Mild myeloid cell myeloid cells Neutrophils pattern progression proteomics provide serum severe COVID-19 patients symptomatic the disease Urine [DOI] 10.1016/j.bbapap.2021.140736 PMC 바로가기 [Article Type] Article