Neutralizing activity – Page 38 – Communicable Diseases Research

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

SARS-CoV-2 및 순환 변이체에 대한 mRNA 백신 유도 항체

Article

Published on 2021-04-012022-09-11
Journal: Nature [Category] MERS, SARS, 변종, 진단,

Presence and short-term persistence of SARS-CoV-2 neutralizing antibodies in COVID-19 convalescent plasma donors

COVID-19 회복기 혈장 기증자에서 SARS-CoV-2 중화 항체의 존재 및 단기 지속성

Article

Published on 2021-04-012022-09-11
Journal: Transfusion [Category] MERS, SARS, 진단, 치료기술,

[키워드] Analysis antibody antibody levels Antibody Response Antibody titers Antigen approved best Blood blood component preparations. CCP Children's Hospital collected convalescent plasma correlation COVID-19 COVID-19 patients criteria detectable Donor donors drug evaluate evaluated FDA FFP transfusion focus food FRNT implementation individual less Live virus majority miss a neutralization neutralization test Neutralizing activity Neutralizing antibody titer neutralizing antibody titers Patient persistence Presence protocol quantitative assay Quantitative assays reduction Regulatory Regulatory and QA robust SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antigen SARS-CoV-2 neutralizing antibody SARS-CoV-2 nucleoprotein sustained therapeutic therapeutic use titer Treatment treatment of COVID-19 Variability
[DOI] 10.1111/trf.16261 PMC 바로가기 [Article Type] Article

Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

1,051명의 COVID-19 환자로부터 구성된 SARS-CoV-2 스파이크 단백질의 선형 에피토프 풍경

Article

Published on 2021-03-302022-09-12
Journal: Cell Reports [Category] SARS, 진단,

Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

Article

Published on 2021-03-292022-10-28
Journal: Vaccines [Category] COVID-19,

[키워드] activity acute respiratory syndrome adjuvant aged mice antibodies approved B cell cellular immunity coronavirus domain ectodomain Effect effective Efficacy Emergency use full-length globe High dose humans IgG antibody IgG1 IgG2a immune responses immunogenic immunogenicity information inhibiting interferon-γ isotypes low dose mice Neutralizing Neutralizing activity pandemic disease RBD-hACE2 inhibition Receptor binding domain Result S1 and S2 SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike-specific SARS-CoV-2 vaccine secreting spike subunit T cell the S1 subunit vaccination Vaccine vaccine antigen vaccine candidate vaccine dose
[DOI] 10.3390/vaccines9040316 PMC 바로가기 [Article Type] Article

Generation of recombinant hyperimmune globulins from diverse B-cell repertoires

Article

Published on 2021-03-272022-10-04
Journal: Nature biotechnology [Category] MERS, SARS, 진단,

SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma

장 B 세포 림프종이 있는 이탈리아의 증상이 있는 고양이의 SARS-CoV-2 감염 및 항체 반응

Case Reports

Published on 2021-03-232022-09-01
Journal: Viruses [Category] SARS, 진단, 치료기술,

[키워드] ( RdRP acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-SARS-CoV-2 antibody assumption B-cell lymphoma best cats Chain Reaction clinical condition clinical disease Clinical signs close contact Comorbidities Comorbidity companion animal condition contact with coronavirus coronavirus disease Coronavirus-2 cough COVID-19 detectable discharge disease domestic cat envelope Evidence gastrointestinal disease Human human-to-feline transmission IgG Immunoglobulin Infection intestinal investigated Italy knowledge molecular Neutralizing activity ocular oropharyngeal swab pandemic polymerase chain polymerase chain reaction positive provide RBD RdRP real-time reverse transcriptase Receptor binding domain reported respiratory respiratory tract response reverse transcriptase Reverse transcriptase polymerase chain reaction RNA-dependent RNA polymerase RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral RNA Serological testing serology Seropositivity severe acute respiratory syndrome Coronavirus sneeze susceptible sVNT tested Transmission Viral Virus neutralization
[DOI] 10.3390/v13030527 PMC 바로가기 [Article Type] Case Reports

Association of Age With SARS-CoV-2 Antibody Response

SARS-CoV-2 항체 반응과 연령의 연관성

Research

Published on 2021-03-222022-09-12
Journal: JAMA Network Open [Category] SARS, 진단,

[키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adolescent adolescents and adults Adults age Analysis antibody Antibody binding Antibody Response Antibody responses Antibody test antibody test result antibody tests association avidity children Cohort collected coronavirus correlated cross-sectional cross-sectional study disease evaluated Evidence exhibited Female patients finding group groups hospital IgG IgG level IgG levels immune response Importance IQR lower risk lowest management measure median Mild symptom mild symptoms moderate negative correlation Neutralizing activity neutralizing antibody New York City not significant objective participant Patient patient population patients pediatric Pediatric patient performed Point populations positive correlation profile quantity relative fluorescence unit relative fluorescence units Relevance Respiratory disease response responses Result RFU SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody responses SARS-CoV-2 antibody test SARS-CoV-2 antibody tests SARS-CoV-2 IgG SARS-CoV-2 viral sera Seroprevalence setting severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe respiratory disease SNAb subset Vaccine development was performed
[DOI] 10.1001/jamanetworkopen.2021.4302 PMC 바로가기 [Article Type] Research

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

SARS-CoV-2 감염은 증상이 있는 COVID-19 후 회복기 환자에서 체액성 면역 반응을 유도합니다

Article

Published on 2021-03-222022-09-10
Journal: Nature Communications [Category] SARS, 진단, 치료기술, 치료법, 치료제,

[키워드] Anti-spike antibodies antibody Antibody Response Antibody responses binding convalescent patient Course COVID-19 COVID-19 disease COVID-19 patient detectable disease onset domain humoral immune response Humoral immunity IgG IgG response IgG responses IgM Immunity Immunoglobulin immunoglobulin M induce large cohort longitudinal change longitudinal changes magnitude Most patients neutralize Neutralizing neutralizing activities Neutralizing activity Neutralizing antibodies neutralizing antibody nucleocapsid observation period patients patients with COVID-19 Protein RBD recognizing recovered patient recovered patients response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody specific antibodies specific IgM sustained symptomatic symptomatic COVID-19 the SARS-CoV-2 These data undetectable viral infection virus
[DOI] 10.1038/s41467-021-22034-1 PMC 바로가기 [Article Type] Article

A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2

항체 중화를 위한 신속하고 효율적인 스크리닝 시스템 및 SARS-CoV-2에 대한 적용

Immunology

Published on 2021-03-222022-09-12
Journal: Frontiers in Immunology [Category] SARS, 진단,

Detection and Genome Sequencing of SARS-CoV-2 in a Domestic Cat with Respiratory Signs in Switzerland

스위스의 호흡기 증상이 있는 집 고양이에서 SARS-CoV-2의 검출 및 게놈 시퀀싱

Case Reports

Published on 2021-03-172022-09-10
Journal: Viruses [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 addition analyzed Antibody testing apathy Asymptomatic Awareness cats close contact collected companion animals conditions contact with Contamination coronavirus coronavirus disease Coronavirus-2 COVID-19 demonstrated detection domestic cat fecal human-to-feline transmission inappetence Infection Lineage measure nasal swab Neutralizing activity next generation sequencing nucleotide observé One-Health oral swab polymorphism positive RBD Receptor binding domain remained respiratory Respiratory Sign respiratory tract infection RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 S1 SARS-CoV-2 viral RNA sequence Sequencing serology Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 single nucleotide Single nucleotide polymorphism sneezing SNP susceptible Swab swab sample Switzerland tested upper respiratory tract upper respiratory tract infection Viral viral genome sequence Viral RNA
[DOI] 10.3390/v13030496 PMC 바로가기 [Article Type] Case Reports