proteomics – Page 38 – Communicable Diseases Research

Altered high-density lipoprotein composition and functions during severe COVID-19

심각한 COVID-19 동안 변경된 고밀도 지단백질 구성 및 기능

Article

Published on 2021-01-272022-09-10
Journal: Scientific Reports [Category] 유전자 메커니즘,

[키워드] Admission affecting Alpha Altered amyloid A Analysis Anti-inflammatory antioxidant antitrypsin Apolipoprotein Apoptosis Biomarkers cadherin changes in conditions consequence controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Day Decreased Endothelial cell endothelial cells exposure to function HDL HDL-C HDLs healthy subjects high-density initial intensive care intensive care unit less lipid metabolism mass spectrometry pandemic Particle Patient patients worldwide permeability plasma Protective Protein proteome Proteomic analysis proteomics pulmonary damage reported SARS-CoV-2 serum amyloid severe COVID-19 severe COVID-19 patient severe COVID-19 patients Sex TNFα VE-cadherin viral infection was performed
[DOI] 10.1038/s41598-021-81638-1 PMC 바로가기 [Article Type] Article

Proteomic Approaches to Study SARS-CoV-2 Biology and COVID-19 Pathology

Perspective

Published on 2021-01-192023-06-15
Journal: Journal of Proteome Research [Category] MERS,

[키워드] Biomarker discovery COVID-19 Drug discovery host response mass spectrometry protein−protein interactions proteomics SARS-CoV-2 structural proteomics virus−host interactions
[DOI] 10.1021/acs.jproteome.0c00764 PMC 바로가기 [Article Type] Perspective

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis

바이러스-숙주 상호작용 및 단백질체 조사, SARS-CoV-2 발병에 영향을 미치는 잠재적인 독성 요인 밝혀

Article

Published on 2021-01-152022-09-11
Journal: Med (New York, N.Y.) [Category] SARS, 유전자 메커니즘,

[키워드] Academy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 antiviral therapy Appointment Blood coagulation CAS caused cellular challenge chemotaxis China Chinese clinical Coagulation Commission contribute coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patients cytokine Cytokine storms development downregulation effective facilitate Factor foundation global public health Host host inflammatory response host protein host proteins IL-8 Infrastructure Innovative Research institution interact interactome interleukin interleukin-8 lack learning maintenance Major mechanism molecular mechanism mononuclear cell natural neutrophil neutrophil activation Neutrophils NF-κB NKRF non-structural protein nsp10 pandemic PBMC PBMCs Peripheral blood Potential Professor Program Protein proteome proteomics pursuit representing research and development resource respiratory reveal SARS-CoV-2 SARS-CoV-2 pathogenesis Scholar Science Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe COVID-19 Shanghai Signaling significantly SII survey T cell T cell receptor target team technology therapeutic interventions Transmission Trigger triggers university upregulation was used
[DOI] 10.1016/j.medj.2020.07.002 PMC 바로가기 [Article Type] Article

Role of Multiomics Data to Understand Host–Pathogen Interactions in COVID-19 Pathogenesis

Review

Published on 2021-01-112023-06-15
Journal: Journal of Proteome Research [Category] MERS,

[키워드] altered biomolecules COVID-19 immune response mass spectrometry metabolomics Pathways Proteome microarray proteomics SARS-CoV-2
[DOI] 10.1021/acs.jproteome.0c00771 PMC 바로가기 [Article Type] Review

A proteomic glimpse into the effect of antimalarial drugs on Plasmodium falciparum proteome towards highlighting possible therapeutic targets

Article

Published on 2021-01-092024-08-28
Journal: Pathogens and Disease [Category] 말라리아,

[키워드] Antimalarial compounds Plasmodium falciparum proteomics therapeutic targets

Pathological features of COVID-19-associated liver injury—a preliminary proteomics report based on clinical samples

Letter

Published on 2021-01-082022-10-29
Journal: Signal Transduction and Targeted Therapy [Category] COVID-19,

[키워드] clinical sample feature Infection Infectious diseases liver pathological proteomics Systems biology
[DOI] 10.1038/s41392-020-00406-1 PMC 바로가기 [Article Type] Letter

‘The long tail of Covid-19’ – The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients

'코로나19의 롱테일' - 무증상 및 경증 환자에서 SARS-CoV-2 감염 후 염증 반응 연장 감지

Brief Report

Published on 2021-01-082022-09-11
Journal: F1000Research [Category] MERS, 치료기술, 치료제,

Mapping the SARS-CoV-2–Host Protein–Protein Interactome by Affinity Purification Mass Spectrometry and Proximity-Dependent Biotin Labeling: A Rational and Straightforward Route to Discover Host-Directed Anti-SARS-CoV-2 Therapeutics

SARS-CoV-2–숙주 단백질–단백질 상호작용체 매핑(Affinity Purification Mass Spectrometry 및 Proximity-Dependent Biotin Labeling: Host-Directed Anti-SARS-CoV-2 치료제 발견을 위한 합리적이고 간단한 경로)

Review

Published on 2021-01-072022-09-10
Journal: International Journal of Molecular Sciences [Category] 신약개발, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advent affinity Affinity purification affinity-purification mass spectrometry Antiviral approach approved drug cellular cellular processe cellular processes coronavirus coronavirus disease COVID-19 Drug discovery Drug repurposing effective emerging experiment Follow-up Generation help high resolution Host host cell host cells host protein identify Interaction interactome life cycle mapping mass mass spectrometry mirage offer outbreak PPI protein interactions protein–protein interactions protein–protein interaction proteomics proximity-dependent biotin labeling (BioID) reduce regulated respiratory route SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spectrometry target targets therapeutic option therapeutic targets Therapeutics Viral viral life cycle virus virus entry virus–host interaction virus–host interactions
[DOI] 10.3390/ijms22020532 PMC 바로가기 [Article Type] Review

Exploring the magic bullets to identify Achilles’ heel in SARS-CoV-2: Delving deeper into the sea of possible therapeutic options in Covid-19 disease: An update

SARS-CoV-2에서 아킬레스건을 식별하기 위한 마법의 총알 탐색: Covid-19 질병에서 가능한 치료 옵션의 바다 더 깊이 탐구: 업데이트

Review

Published on 2021-01-012022-09-11
Journal: Food and chemical toxicology : an international jo [Category] SARS, 신약개발, 치료제,

Proteomics in the COVID-19 Battlefield: First Semester Check-Up

COVID-19 전장에서의 단백질체학: 첫 학기 검진

Review

Published on 2021-01-012022-09-11
Journal: Proteomics [Category] SARS, 유전자 메커니즘, 치료기술, 치료제,