Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysisResearch Published on 2020-06-182022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 2019-nCoV 95% CI Acute kidney injury AKI Analysis association Continuous Continuous renal replacement therapy COVID-19 COVID-19 patient COVID-19 patients critical cases CRRT database determine eligible incidence kidney dysfunction Meta-analysis Mild moderate non-severe patient non-survivor Non-survivors Patient patients Prevalence proportion renal impairment renal replacement therapy reported required Result SARS-CoV-2 searched severe cases severe patients severity and prognosis survivor Survivors systematic review Urine was performed [DOI] 10.1186/s13054-020-03065-4 PMC 바로가기 [Article Type] Research
COVID-19 findings identified in chest computed tomography: a pictorial essayReview Published on 2020-06-182022-10-31 Journal: Einstein [Category] COVID-19, MERS, SARS, [키워드] addition Care caused Chest clinical symptom clinician complications Computed tomography Coronavírus coronavirus Coronavirus infections COVID-19 described DESSA Diagnosis differential diagnose disease false-negative Health Infecções por coronavírus initial involved Isolation knowledge Laboratory Laboratory tests manifestation Multidetector computed tomography New coronavirus Pandemia pandemic Patient physician polymerase chain Radiologists severe cases Spread the disease the patient Tomografia computadorizada multidetectores [DOI] 10.31744/einstein_journal/2020RW5741 PMC 바로가기 [Article Type] Review
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global CommunityReview Article Published on 2020-06-162022-10-29 Journal: Research [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV amplification antibodies antigens cause caused clinical trial coronavirus Coronavirus disease 2019 COVID-19 CRISPR Critical detect detection diagnosis of COVID-19 difficulty breathing Disease diagnosis dry cough effective effort expand fatality Fever Health Intervention isothermal amplification Loss of Smell nucleic acids Other outbreak outcomes palindromic repeat pandemic polymerase Potential treatment progression reduce Respiratory illness RPA RT-PCR severe cases Spread Symptom Treatment Vaccine viral disease WHO World Health Organization [DOI] 10.34133/2020/6925296 PMC 바로가기 [Article Type] Review Article
CT findings of severe novel coronavirus disease (COVID-19): A case report of Heilongjiang Province, ChinaCase Report Published on 2020-06-132022-10-28 Journal: Open Medicine [Category] COVID-19, [키워드] 2019 novel coronavirus accompanied acute respiratory distress Case report change China Clinical management Combined consolidation Contact cough COVID-19 CT finding CT findings diagnosed discharged disease early diagnosis fatigue Fever GGO ground-glass opacity include initial symptom leukocyte lung Lungs Lymphocyte count manifestation Novel coronavirus novel coronavirus disease novel coronavirus pneumonia nucleic acid test occur patchy Patient Pneumonia positive SARS-CoV-2 SARS-CoV-2 pneumonia severe cases Spread suffered syndrome the disease Treatment Wuhan [DOI] 10.1515/med-2020-0151 PMC 바로가기 [Article Type] Case Report
Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative PhenotypesSARS-CoV-2 감염 및 인간의 정량적 표현형에 관여하는 ACE2 및 TMPRSS2 유전자의 유전적 변이체 간의 연관성 부족Genetics Published on 2020-06-082022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 gene acute respiratory distress acute respiratory distress syndrome angiotensin angiotensin converting enzyme Angiotensin II Anti-inflammatory ARBs ARBs (angiotensin II receptor blockers) association associations Biomarkers blocker carried cause causes Cell chronic inflammation Cohort combination therapies combination therapy coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytokine Cytokines death disease enzyme examined example expression female females flu-like symptoms General population genetic data Genetic predisposition Genetic variant Genetic variation genetics Human human genes hypertension include Infection Invasion male medication medications Mild modulate multifactorial no symptoms NSAIDs (non-steroidal anti-inflammatory drugs) nucleotide outcome phenotype PheWAS Pneumonia priming Quantitative reached receptor Receptor Blockers respiratory distress Respiratory distress syndrome responsible S protein sample sizes SARS-CoV-2 SARS-CoV-2 virus Serine serine protease serine protease TMPRSS2 severe cases severe COVID-19 severity of symptoms significantly Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs syndrome threshold thrombocyte Thrombocytes thrombocytopenia TMPRSS2 Usage Variability variant Variation virus clearance Volunteer while [DOI] 10.3389/fgene.2020.00613 PMC 바로가기 [Article Type] Genetics
Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19Pharmacology Published on 2020-06-052022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] absence Anti-inflammatory anti-SARS-CoV-2 antiviral agent assist attenuate Cell Chloroquine chromone chromones clinical testing complications COVID-19 COVID-19 pandemic drug drugs fatality Inflammation interstitial pneumonia Intervention lack life-threatening limit Lung injury Mast cells Medicine pharmacological progression repositioning Respiratory complications Safe SARS‐CoV‐2 infection severe cases severity Tocilizumab treat Treatment Vaccine viral growth virus replication [DOI] 10.3389/fphar.2020.00854 PMC 바로가기 [Article Type] Pharmacology
The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019코로나 바이러스 질병 2019의 중증 사례 모니터링에서 인터루킨-6의 역할Article Published on 2020-06-052022-09-25 Journal: EMBO Molecular Medicine [Category] SARS, 바이오마커, 진단, [키워드] analyzed baseline Biomarker body temperature C‐reactive protein can be used changes in Chest computed tomography coronavirus disease Coronavirus disease 2019 COVID CRP Cytokine storm D‐dimer decrease disease disease monitoring Disease progression exacerbated ferritin Hospitalization immunology interleukin‐6 lactate dehydrogenase LDH lymphocytopenia marker Microbiology, Virology & Host Pathogen Interaction Patient patients positively correlated progressed Severe case severe cases severe disease severity Significant significant increase [DOI] 10.15252/emmm.202012421 PMC 바로가기 [Article Type] Article
Clinical and Immune Features of Hospitalized Pediatric Patients With Coronavirus Disease 2019 (COVID-19) in Wuhan, ChinaResearch Published on 2020-06-032022-10-29 Journal: JAMA Network Open [Category] COVID-19, [키워드] acute respiratory syndrome age alanine aminotransferase ALT analyzed Aspartate aminotransferase association AST B cell B cells biochemical Case series case sery caused CD4 Characteristics children CK-MB clinical Clinical characteristics Clinical management collected coronavirus coronavirus disease COVID-19 Critically ill decrease disease severity dysregulation exposure feature finding immune immune response Immunoglobulin Importance Infection Inflammatory cytokine Inflammatory response information interferon γ interquartile range involved laboratory abnormality laboratory-confirmed lactate dehydrogenase LDH liver lymphocyte Lymphocytes lymphopenia measure median Mild mild case mild cases moderate Moderate COVID-19 moderate disease myocardial injury Necrosis neutrophil Neutrophils objective occurred participant Pathogenesis pathogenesis of SARS-CoV-2 pathologic process Patient Pediatric patient Pediatric patients Pneumonia Point positive Relevance reported Result SARS-CoV-2 SARS-COV-2 infection setting severe cases single-center statistically significant difference systemic inflammation T cell T cells with COVID-19 with mild disease Wuhan Wuhan, China [DOI] 10.1001/jamanetworkopen.2020.10895 PMC 바로가기 [Article Type] Research
Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research NetworksShort Communication Published on 2020-06-032022-10-31 Journal: European journal of pediatrics [Category] COVID-19, MERS, SARS, [키워드] 95% CI adolescents Asymptomatic case sery Characteristics children children with COVID-19 Chronic diseases clinical presentation Comorbidities COVID-19 COVID-19 infection Critical Critical disease diagnosed disease enrolled Europe Evidence hospital Hospitalized hospitals Infant intensive care Italian Italy Mild moderate disease network nine outcome pandemic pediatric Population Region Respiratory Support risk risk factor selected severe cases severe disease severity significantly increased supplementary material treated with COVID-19 [DOI] 10.1007/s00431-020-03683-8 PMC 바로가기 [Article Type] Short Communication
Association of hypertension with the severity and fatality of SARS-CoV-2 infection: A meta-analysisOriginal Paper Published on 2020-05-282022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, [키워드] age Analysis association carried CNKI Comorbidity COVID-19 COVID-19 case COVID-19 patient COVID-19 patients COVID-19 severity death Direct disease disease severity Elsevier Evidence fatality heterogeneity higher risk hypertension hypertensive patient Impact library Meta-analysis much higher patients provided reported risk SARS-CoV-2 SARS-COV-2 infection Science severe cases severity Severity rate shown significantly Web of Science [DOI] 10.1017/S095026882000117X PMC 바로가기 [Article Type] Original Paper