Antibody Response Six Months after SARS-CoV-2 mRNA Vaccination in Patients with Inflammatory Bowel Disease염증성 장 질환 환자에서 SARS-CoV-2 mRNA 백신 접종 후 6개월 후 항체 반응Article Published on 2022-07-012022-09-11 Journal: Clinical gastroenterology and hepatology : the off [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-spike antibody anti-spike antibody response antibody kinetics Antibody Response completion coronavirus detectable examined IBD Immunosuppression immunosuppressive medications Inflammatory bowel disease Kinetics medication moderate moderate to severe Month mRNA Patient receive response SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine severe acute respiratory syndrome Coronavirus shown subset the SARS-CoV-2 therapy vaccination Vaccinations vaccine response [DOI] 10.1016/j.cgh.2021.12.045 PMC 바로가기 [Article Type] Article
A Fourth Dose of COVID-19 Vaccine Does Not Induce Neutralization of the Omicron Variant Among Solid Organ Transplant Recipients With Suboptimal Vaccine ResponseCOVID-19 백신의 4차 접종은 최적의 백신 반응을 보이지 않는 고형 장기 이식 수혜자들 사이에서 오미크론 변이체의 중화를 유도하지 않습니다Article Published on 2022-07-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome angiotensin angiotensin-converting enzyme 2 anti-receptor-binding domain Anti-spike anti-spike antibody anti-Spike IgG Antibody Units binding antibody units booster vaccinations change Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine Delta delta variant domain dose ELISA full-length spike protein Health Organization healthy controls high risk Humoral response humoral responses IgG immune evasion Immunoglobulin increase Infection interquartile range Intervention Live virus median multiplex neutralization neutralizing capacity omicron Omicron variant Protective recipient respiratory response Seropositivity significantly increased significantly lower Solid solid organ solid organ transplant Spike proteins surrogate the vaccine Transplant Vaccination strategy Vaccine vaccine dose vaccine strain variant VoC VOCs was measured Wilcoxon signed-rank test World Health Organization [DOI] 10.1097/TP.0000000000004140 PMC 바로가기 [Article Type] Article
Individuals With Weaker Antibody Responses After Booster Immunization Are Prone to Omicron Breakthrough Infections추가 접종 후 항체 반응이 약한 개인은 오미크론 돌발 감염에 걸리기 쉽습니다.Article Published on 2022-06-232022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% confidence interval anti-SARS-CoV-2 IgG antibody Anti-spike anti-spike antibodies anti-spike antibody antibody Antibody titer binding antibody body mass index booster booster vaccination Breakthrough infection breakthrough infections conditions COVID-19 Essen healthcare worker help humoral humoral immune response identify immune independent individual Infection information Level neutralization neutralization capacity occur omicron participant potential risk prone provided response risk routine SARS-CoV-2 SARS-CoV-2 IgG antibody serum sample severe COVID-19 Sex smoking status subject threshold university vaccination vaccination against COVID-19 Vaccine Virus neutralization were measured [DOI] 10.3389/fimmu.2022.907343 PMC 바로가기 [Article Type] Article
BNT162b2 Booster Vaccination Elicits Cross-Reactive Immunity Against SARS-CoV-2 Variants B.1.1.529 and B.1.617.2 in Convalescents of All AgesBNT162b2 부스터 백신 접종은 모든 연령대의 회복기에서 SARS-CoV-2 변이체 B.1.1.529 및 B.1.617.2에 대한 교차 반응성 면역을 유발합니다Observational Study Published on 2022-06-202022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 임상, 치료기술, [키워드] Against analyzed anti-spike antibody antigenic approach B.1.1.529 B.1.617.2 BNT162b2 booster vaccination cellular cohort study component convalescent individual convalescent individuals COVID-19 COVID-19-convalescent individual COVID-19-convalescent individuals cross-reactive immune Delta detectable exhibited full recovery IFN-γ immune response Immunological response inactivated include individual individuals memory memory immune response mRNA mRNA vaccine mRNA vaccines neutralization neutralization capacity no significant differences Older omicron parameter prospective observational cohort SARS-CoV-2 second vaccination secretion serological serological response significant difference South Africa Support vaccination Vaccine variant variants of concern virus VoC whole virus vaccine wild type [DOI] 10.3389/fimmu.2022.920210 PMC 바로가기 [Article Type] Observational Study
Serum Levels of Proinflammatory Lipid Mediators and Specialized Proresolving Molecules Are Increased in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 and Correlate With Markers of the Adaptive Immune Response중증 급성 호흡기 증후군 코로나바이러스 2 환자에서 전염증성 지질 매개체 및 전문 분해 분자의 혈청 수준이 증가하고 적응 면역 반응의 마커와 상관 관계가 있습니다Article Published on 2022-06-152022-09-11 Journal: The Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Anti-inflammatory Anti-nucleocapsid Anti-spike anti-spike antibody assays binding bioactive lipids Clinical outcome collected Concentration Control coronavirus coronavirus 2 died female hospital identify immune immune response Increased innate response Inpatient Level linoleic acid Lipid lipids male mediator molecule Omega pandemic pathogenic inflammation Pathways Patient patients positive correlation processed proinflammatory quantification Quantitative respiratory response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients serum Serum level serum levels severe acute respiratory syndrome Coronavirus Sex significantly higher significantly lower specialized proresolving molecules. symptomatic SARS-CoV-2 infection transition [DOI] 10.1093/infdis/jiab632 PMC 바로가기 [Article Type] Article
Differential antibody response to COVID-19 vaccines across immunomodulatory therapies for multiple sclerosis다발성 경화증에 대한 면역 조절 요법 전반에 걸친 COVID-19 백신에 대한 차별적인 항체 반응Article Published on 2022-06-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] MERS, 진단, [키워드] 95% CI Acetate Analysis analyzed anti-CD20 anti-CD20 therapy anti-spike antibody antibodies antibody Antibody Response Antibody test Antibody testing B-cell benefit booster vaccinations cells cellular clinical Cohort COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines determine evaluate Final fumarate higher odd humoral identify immunomodulatory effects immunomodulatory therapy Immunosuppressed individual interferons Johnson & Johnson lymphopenia median mediated immunity Moderna mRNA Multiple multiple sclerosis multivariable logistic regression multivariate one patient Patient patients Pfizer phosphate populations positive positive antibody response Post-vaccine predicted predictor reduced SAS significantly Studio Therapies therapy Vaccine vaccine dose Viral vector were used [DOI] 10.1016/j.msard.2022.103737 PMC 바로가기 [Article Type] Article
Analysis of a SARS-CoV-2 convalescent cohort identified a common strategy for escape of vaccine-induced anti-RBD antibodies by Beta and Omicron variantsSARS-CoV-2 회복기 코호트 분석에서 베타 및 오미크론 변이체에 의한 백신 유도 항-RBD 항체의 탈출을 위한 공통 전략 확인Article Published on 2022-06-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Ad26 Ad26.COV2.S allergy Alpha Analysis anti-RBD Anti-RBD antibody anti-spike antibody antibody Antibody binding Antibody Response antibody response against Antibody titer Antibody titers assays Beta blood draw blood draws blood sample BNT162b2 Boston Cohort collected convalescent COV2.S COVID COVID-19 cross-reactive antibodies cross-reactive antibody Delta Donor evade evaluate expected fraction hybrid Hybrid immunity Immune escape immune evasion Immunity increase increase in Infectious disease Infectious diseases initial limitation Massachusett mRNA mRNA-1273 mutant Mutation neutralization Neutralization escape mutations omicron Omicron variant plasma polyclonal polyclonal antibody Post-infection proportion proportions Proteins RBD RBDs Re-infection readiness Receptor binding domain residue residues SARS-CoV-2 SARS-CoV-2 variants spike Spike protein Structural analysis the spike protein vaccination Vaccine induced antibody titers. variant variants variants of concern were excluded were used [DOI] 10.1016/j.ebiom.2022.104025 PMC 바로가기 [Article Type] Article
Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 VaccineBNT162b2 백신의 추가 용량에 따른 CoronaVac에 대한 SARS-CoV-2 항체 반응의 역학Article Published on 2022-06-012022-09-12 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome anti-spike antibody antibody Antibody Response BNT162b2 BNT162b2 vaccine booster dose CoronaVac coronavirus coronavirus disease COVID-19 Dynamics evaluated healthcare Healthcare workers of BNT162b2 respiratory infections response robust SARS-CoV-2 second dose severe acute respiratory syndrome coronavirus 2 the SARS-CoV-2 Vaccine vaccine-preventable diseases viruses zoonoses [DOI] 10.3201/eid2806.220061 PMC 바로가기 [Article Type] Article
Kinetics and Persistence of the Cellular and Humoral Immune Responses to BNT162b2 mRNA Vaccine in SARS-CoV-2-Naive and -Experienced Subjects: Impact of Booster Dose and Breakthrough InfectionsSARS-CoV-2-나이브 및 -경험 대상자에서 BNT162b2 mRNA 백신에 대한 세포 및 체액 면역 반응의 동역학 및 지속성: 추가 용량 및 돌발 감염의 영향Article Published on 2022-05-312022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] administration age analyzed Anti-nucleocapsid antibodies anti-SARS-CoV-2 anti-spike antibodies anti-spike antibody antibodies antibody association Belgium benefit blood sample Blood samples blood sampling BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine booster booster dose booster doses breakthrough infections cell-mediated immune response cellular cellular and humoral immune response Cellular immune response cellular immune responses collected COVID-19 COVID-19 vaccine DiaSorin dose Elecsy enrolled evaluated greater HCW HCWs Healthcare system healthcare worker Healthcare workers help Human humoral Humoral and cellular immune responses humoral immune response Humoral response IFN-γ IgG immune protection immune response immune responses immunization immunogenicity Impact implication increase in individual level individuals Infection initial Kinetics LIAISON Lymphocytes management mandatory mRNA vaccination mRNA vaccine naïve naïve individuals natural infection Neutralization assay neutralization capacity Neutralizing antibodies pandemic participant Participants Peripheral blood peripheral blood lymphocyte peripheral blood lymphocytes persistence Prevent Prospective Study Qiagen QuantiFERON quantified reduce regimen response SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose secretion severe COVID-19 significantly higher tested the SARS-CoV-2 triggering understanding university vaccination vaccine dose variant Vero E6 was performed [DOI] 10.3389/fimmu.2022.863554 PMC 바로가기 [Article Type] Article
Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects백신 접종 대상체의 체액성 면역 프로파일링을 위한 SARS-CoV-2 변이 단백질 마이크로어레이 개발Article Published on 2022-05-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 anti-spike antibody antibody Antibody responses AZD1222 B.1.1.7 B.1.351 B.1.617 B.1.617.1 B.1.617.2 binding ChAdOx1 chimeric collected correlated D614G demonstrated develop development domain Drug development Extracellular globe host receptor Humoral immunity Humoral response humoral responses IgA IgG IgM isotype IgM isotypes immune inhibiting Microarray MONITOR mRNA-1273 mutant neutralization neutralizing activities Neutralizing activity neutralizing antibody P.1 platform Protein protein microarray Research SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serology serum spike variants subject the antibody response vaccinated individual vaccination Vaccine Vaccines variant variants variants of concern Virus neutralization wild-type [DOI] 10.1016/j.bios.2022.114067 PMC 바로가기 [Article Type] Article