Strong immunogenicity of heterologous prime-boost immunizations with the experimental vaccine GRAd-COV2 and BNT162b2 or ChAdOx1-nCOV19Brief Communication Published on 2021-11-042022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] adhere antibody BNT162b2 boost Cellular immune response chose clinical trial COVID-19 vaccination eight Heterologous heterologous prime-boost immunization humoral immune response Italian National public health receiving single dose small sample size Strong Support T-cell Response Vaccine vaccine candidate vaccine platform Vaccines Volunteer [DOI] 10.1038/s41541-021-00394-5 PMC 바로가기 [Article Type] Brief Communication
DeepImmuno: deep learning-empowered prediction and generation of immunogenic peptides for T-cell immunityDeepimmuno : T- 세포 면역을위한 면역 원성 펩티드의 딥 러닝에 대한 예측 및 생성Problem Solving Protocol Published on 2021-11-032022-09-10 Journal: Briefings in Bioinformatics [Category] MERS, SARS, 변종, [키워드] AdaBoost adaptive immune system addition Algorithms alleles Antigen antigen recognition antigens approach best binding Cancer Cancer immunotherapy Cell chose CNN computational method Computational methods conducted Convolutional neural network COVID-19 dataset datasets deep learning Dengue dengue virus distribution elicit FIVE foreign antigen foreign antigens forest GAN generative adversarial network human leukocyte antigen immunogenic peptide immunogenic potential immunogenicity Impact independent killing lack leukocyte life-threatening neoantigen Pathogens peptide peptides Physicochemical properties physicochemical property predict Random forest residual residue SARS-CoV-2 SARS-CoV-2 variants seeking sequence source code Support support vector machine T-cell T-cell immunity T-cell Response T-cells targeted therapy Vaccine [DOI] 10.1093/bib/bbab160 PMC 바로가기 [Article Type] Problem Solving Protocol
How Do Polish Students Manage Emotional Distress during the COVID-19 Lockdown? A Web-Based Cross-Sectional StudyArticle Published on 2021-10-262022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age Anxiety anxiety symptom brief-COPE caused choice chose contributing to coping strategies Coping strategy COVID-19 COVID-19 pandemic cross-sectional DASS DASS-21 Depression disorder disorders distress emotional emotional distress evaluate Factor female highest Intervention inventory lockdown loneliness male men outbreak pandemic Planning Prevent Psychiatric psychological support SARS-CoV-2 severity Stress student total score turn women [DOI] 10.3390/jcm10214964 PMC 바로가기 [Article Type] Article
Epidemiological Analysis of SARS-CoV-2 Transmission Dynamics in the State of Odisha, India: A Yearlong Exploratory Data Analysis인도 오디샤 주의 SARS-CoV-2 전파 역학 분석: 1년 동안의 탐색적 데이터 분석Article Published on 2021-10-252022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 변종, [키워드] age Analysis association average cause chose conducted confirmed case confirmed cases Coronavirus infection COVID-19 Critical dataset datasets death death rates demographic characteristics Dynamics Effect environmental factor environmental factors epidemiological epidemiological surveillance Factor Gender global public health incidence rate incidence rates India lesson Local matter multivariate New York Occurrence pandemic pattern persistence population density population-based studies predict prevention Relative risk reported Research risk Risk assessment SARS-CoV-2 SARS-CoV-2 transmission second wave Sex sex ratio Spread state suggested Surveillance temperature temperature effect timeline USA variant variants Viral Viral transmission [DOI] 10.3390/ijerph182111203 PMC 바로가기 [Article Type] Article
Assessment of Out-of-Pocket Spending for COVID-19 Hospitalizations in the US in 2020Research Published on 2021-10-182022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] age assessment Care chose clinician COVD-19 COVID-19 COVID-19 hospitalization cross-sectional database defined exceeded finding hospital Hospitalization hospitalizations hospitals Importance IQVIA male management measure Medicare National objective participant Patient patients patients hospitalized Point provided Relevance reported representing Result setting the mean Total Transport used data [DOI] 10.1001/jamanetworkopen.2021.29894 PMC 바로가기 [Article Type] Research
Attitudes of Healthcare Professionals and General Population Toward Vaccines and the Intention to Be Vaccinated Against COVID-19 in SpainPublic Health Published on 2021-10-082022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Against associations Attitude Attitudes benefit calculated Care chose conducted COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional Developing Effect General population Generalized Health healthcare Healthcare professional healthcare professionals higher risk highest Immunity intention to vaccinate linear mixed model lowest natural immunity offered Population positive attitude professional professionals public health refusal rejection Spain Spanish statistically significant subject vaccination Vaccine Vaccines was used [DOI] 10.3389/fpubh.2021.739003 PMC 바로가기 [Article Type] Public Health
Effects of buprenorphine/lorcaserin mixtures on preference for heroin, cocaine, or saline over food using a concurrent choice procedure in rhesus monkeysResearch article Published on 2021-10-012022-10-05 Journal: Drug and alcohol dependence [Category] 비임상, [키워드] Adding administration Alter attenuate Buprenorphine chose Critical Daily decrease disorder drug Effect effective Effectiveness Epidemic investigated less Lorcaserin medication medications offer Opioid use disorder outcome pharmacological preclinical studies Prevalence receptor reduced Result Rhesus monkey Rhesus monkeys selective Substance use Treatment Variability [DOI] 10.1016/j.drugalcdep.2021.108991 [Article Type] Research article
Association between Reactogenicity and Immunogenicity after Vaccination with BNT162b2Article Published on 2021-09-272022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome Adverse reaction Adverse reactions age Antibody Response association binding domain BNT162b2 center chose Control coronavirus COVID-19 detectable humoral humoral immune response IgG titer immune response immunogenicity information inhibitory concentration injection median men moderate neutralization activity participant provided RBD reactogenicity resulting robust SARS-CoV-2 SARS-CoV-2 RBD second vaccination severe adverse reaction Sex sick significantly higher university vaccination vaccinee women [DOI] 10.3390/vaccines9101089 PMC 바로가기 [Article Type] Article
Exposure to COVID-19 is associated with increased altruism, particularly at the local levelArticle Published on 2021-09-232022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] chose country COVID-19 COVID-19 pandemic Donor effort engage ENhance environmental exposure experiment exposure to had no Human behaviour identity influence International Italy Local National participant Psychology question Social evolution target theory [DOI] 10.1038/s41598-021-97234-2 PMC 바로가기 [Article Type] Article
Diagnosing a Patient with Erdheim-Chester Disease during the COVID-19 PandemicCase Report Published on 2021-09-222022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] Affect Anemia Case report characterized chose chronic disease condition coronavirus disease Course COVID-19 COVID-19 pandemic diagnose Diagnosis diagnostic disease Disruption ECD effort Erdheim-Chester disease Fever healthcare service Healthcare system Hospitalization male Mild neoplasm Non-COVID-19 organ pandemic Patient performed Positron presentation Prevent rare disease repeated required resulting SARS-CoV-2 the patient tissue tissue biopsy tomography Treatment [DOI] 10.3390/medicina57101001 PMC 바로가기 [Article Type] Case Report