Pituitary Apoplexy Attributed to COVID-19 Infection in the Absence of an Underlying Macroadenoma or Other Identifiable CauseNeurology Published on 2021-02-122022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absence acute respiratory syndrome Apoplexy cause causes clinical complication coronavirus coronavirus disease COVID-19 knowledge Macroadenoma Manifestations Neurological complications neurosurgery Novel coronavirus Other pathophysiology patients with COVID-19 Pituitary pituitary apoplexy raise responsible SARS-CoV-2 while [DOI] 10.7759/cureus.13315 PMC 바로가기 [Article Type] Neurology
Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complicationsCOVID-19 임상 합병증을 표적으로 하는 SARS-CoV-2 수명 주기, 병태생리학 및 합리화된 치료에 대한 통찰력Review Published on 2021-01-122022-08-13 Journal: Journal of Biomedical Science [Category] Biochemistry, COVID-19, MERS, [키워드] “cytokine storm” ACE2 activate Adaptive immune response adverse effect adverse effects approach approaches ARDS AT1R clinical complication collateral tissue damage complications of COVID-19 COVID-19 CTSB Cytokine storm distress expression gastrointestinal tract Host human gene hyper-cytokinemia immune responses Infection infection rate infection rates Inflammation inflammatory immune response insight life cycle life-threatening mitigate multi-organ collapse organotropism of SARS-CoV-2 pathobiology of COVID-19 Pathologies pathophysiology Phase 1 Phase 2 Propagation respiratory respiratory and gastrointestinal tract respiratory distress Respiratory distress syndrome robust SARS-CoV-2 SARS-CoV-2 life cycle Sex Signaling Support suppress syndrome systemic failure tissue tissue damage tissues TMPRSS2 Treatment Trigger triggered triggers two-phase disease Viral viral infection virus virus antigen presentation virus transmission [DOI] 10.1186/s12929-020-00703-5 PMC 바로가기 [Article Type] Review
Phosphatidylserine inside out: a possible underlying mechanism in the inflammation and coagulation abnormalities of COVID-19포스파티딜세린 인사이드 아웃: COVID-19의 염증 및 응고 이상에서 가능한 기본 메커니즘Review Published on 2020-12-272022-09-10 Journal: Cell Communication and Signaling : CCS [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Abnormalities abnormality ACE2 Activation Acute inflammation ADAM17 ADAMTS13 addition aggregation association biochemical C reactive protein cascade cause cell membrane clinical complication clinical complications Coagulation coagulation cascade coronavirus coronavirus disease COVID-19 COVID-19 pathophysiology Cytokines damage death DIC-COVID-19 EGFR Endothelial cell endothelial cells Endothelium explained expression extrinsic pathway factor VII Health humans IFN-γ IL-1β IL-6 IL-6R IL-8 immune induce infected cell Inflammation Inflammatory response inhibitory action involved management mechanism membrane monocyte pathophysiological pathophysiology Phosphatidylserine plasma Platelet Platelets pro-inflammatory cytokines pro-inflammatory molecule pro-inflammatory molecules SARS-CoV-2 Spread Support the cell the SARS-CoV-2 thrombi tissue Tissue Factor TNF-α Vascular Viral viral infection [DOI] 10.1186/s12964-020-00687-7 PMC 바로가기 [Article Type] Review
Physiology of Midkine and Its Potential Pathophysiological Role in COVID-19Physiology Published on 2020-12-222022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] angiotensin autoimmune condition autophagy cascade cause cellular clinical complication coagulative coronary syndrome COVID-19 cytokine dependent on Disseminated intravascular coagulation distress dysregulation Effect effector cells elicited facilitate fibrinolytic growth factor highlight Hyperactivation hypoxia immune immune responses include increases in induce Inflammatory literature mechanism mechanisms mediators of inflammation Midkine myocarditis NETs, autophagy neutrophil infiltration Neutrophils New coronavirus Occurrence organs pathogen clearance pathological condition pathophysiological physiological Physiology Potential pro-inflammatory cytokines pulmonary fibrosis receptor Renin replicate response role SARS-CoV2 SARS-CoV2 infection severe cases severe pneumonia similarity System target tissues Thromboembolism tissue tissue damage virus entry [DOI] 10.3389/fphys.2020.616552 PMC 바로가기 [Article Type] Physiology
Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms사이토카인 폭풍 길들이기: 심각한 COVID-19 증상의 약화 및 예방을 위한 몬테루카스트 용도 변경Article Published on 2020-12-012022-09-11 Journal: Drug discovery today [Category] 신약개발, [키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approved Asthma attenuation characterized clinical complication Clinical outcome clinical outcomes coronavirus COVID-19 cytokine cytokine production cytokine profile Cytokine storm decrease Hyperinflammatory immune response infections Inflammation involved mediators modulate Montelukast NF-κB NF-κB activation nuclear Patient proinflammatory mediator proinflammatory mediators Prophylaxis protein complex reduction in respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe COVID-19 symptom suppress symptom severity Viral viral infections [DOI] 10.1016/j.drudis.2020.09.013 PMC 바로가기 [Article Type] Article
Nitric oxide (NO) and nanoparticles – Potential small tools for the war against COVID-19 and other human coronavirus infectionsReview Published on 2020-10-182022-10-04 Journal: Virus research [Category] MERS, 치료제, [키워드] 3–dioxygenase Abstract AgNPs, Silver Nanoparticles AgNPsSilver Nanoparticles Antiviral blood pressure challenge clinical complication clinical setting concerning Copper Nanoparticles coronavirus Coronavirus infection Coronavirus infections COVID-19 CuNPs, Copper Nanoparticles CuNPsCopper Nanoparticles Donor Effect FDA, US Food and Drug Administration FDAUS Food and Drug Administration highlight IDO, Indoleamine 2,3–dioxygenase IDOIndoleamine 2 immunological Indoleamine 2 Inducible NO Synthase Inhaled Inhaled nitric oxide iNOS, Inducible NO Synthase iNOSInducible NO Synthase Nanomaterial Nanoparticles nitric oxide Nitrogen Reactive Species NO, Nitric Oxide NOx, Nitrogen Reactive Species NONitric Oxide NOxNitrogen Reactive Species O2•−, Superoxide O2−Superoxide ONOO−, Peroxynitrite ONOO−Peroxynitrite Patient Peroxynitrite Perspective Potential Regulation reported Research respiratory viral diseases Ribonucleic acid RNA, Ribonucleic acid RNARibonucleic acid S-nitroso-N-acetylpenicillamine SARS-CoV SARS-CoV-2, Severe Acute Respiratory Syndrome Corona Virus 2 SARS-CoV-2Severe Acute Respiratory Syndrome Corona Virus 2 Severe Acute Respiratory Syndrome Corona Virus 2 Side effects Silver nanoparticles SNAP, S-nitroso-N-acetylpenicillamine SNAPS-nitroso-N-acetylpenicillamine Superoxide sustained therapeutic effect Treatment Ultraviolet radiation A US Food and Drug Administration UVA, Ultraviolet radiation A UVAUltraviolet radiation A WHO, World Health Organization WHOWorld Health Organization World Health Organization [DOI] 10.1016/j.virusres.2020.198202 PMC 바로가기 [Article Type] Review
Successful recovery from severe COVID-19 pneumonia after kidney transplantation: The interplay between immunosuppression and novel therapy including tocilizumab신장 이식 후 중증 코로나19 폐렴에서 성공적으로 회복: 면역억제제와 토실리주맙을 포함한 새로운 요법 사이의 상호작용Case Reports Published on 2020-10-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] MERS, SARS, 진단, 치료제, [키워드] antiviral drug antiviral drugs Atypical clinical complication coronavirus COVID-19 Hydroxychloroquine Immunosuppressed immunosuppressed patient immunosuppressed patients Immunosuppression Interaction investigated kidney Kidney transplantation Lopinavir Lopinavir/ritonavir management pandemic Patient Ritonavir SARS-COV-2 infection severe COVID-19 Severe COVID-19 pneumonia steroid therapy Tocilizumab treated Treatment [DOI] 10.1111/tid.13334 PMC 바로가기 [Article Type] Case Reports
Pathogenesis, clinical manifestations and complications of coronavirus disease 2019 (COVID-19)Review Published on 2020-08-272022-10-31 Journal: Future Microbiology [Category] COVID-19, MERS, SARS, [키워드] article Beta coronaviruses cardiovascular Central nervous system clinical complication clinical complications Complication conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Frequency Google Scholar highlight infective involved kidneys liver lung mechanism Pathogenesis pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 respiratory SARS-CoV-2 severity similarity [DOI] 10.2217/fmb-2020-0110 PMC 바로가기 [Article Type] Review
Secondary Bacterial Infections in Patients With Viral PneumoniaMedicine Published on 2020-08-052022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Administered Antibiotic resistance bacterial pathogen Case report cephalosporin clinical complication Clinical data clinician COVID-19 COVID-19 patients described disease include infections Influenza Klebsiella pneumoniae knowledge MERS-CoV mortality rate MOST outcomes patients with pneumonia positive prevalent prophylactic antibiotics prophylactic measure provided pulmonary pulmonary viral pulmonary viruses Research respiratory virus SARS SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 secondary secondary bacterial infection Secondary bacterial infections Secondary infection secondary infections Staphylococcus aureus strain treated patient Treatment vancomycin Viral pneumonia [DOI] 10.3389/fmed.2020.00420 PMC 바로가기 [Article Type] Medicine
Rate of venous thromboembolism in a prospective all-comers cohort with COVID-19Article Published on 2020-07-022022-10-30 Journal: Journal of Thrombosis and Thrombolysis [Category] COVID-19, MERS, SARS, [키워드] Admission Analysis analyzed association clinical complication Coagulopathy Cohort Control control group control groups correlated Course courses COVID-19 COVID-19 group critically ill patients D-dimer D-dimers diagnosed disease disease severity evaluate Follow-up follow-up period ICU in both group Mortality occurred Patient positive presenting Rate reported SARS-CoV-2 severity single-center study statistically significant Symptoms variety Venous Thromboembolism VTE with COVID-19 [DOI] 10.1007/s11239-020-02202-8 PMC 바로가기 [Article Type] Article