Long-term quantitative assessment of anti-SARS-CoV-2 spike protein immunogenicity (QUASI) after COVID-19 vaccination in older people living with HIV (PWH)Article Published on 2022-09-212022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] age analyzed anti-SARS-CoV-2 Anti-spike Antiretroviral therapy black BNT162b2 booster CD4 CD8 cells clinically COVID-19 COVID-19 vaccination COVID-19 vaccine decrease demographics detectable dose exploratory female HIV Humoral immunity IgG IgG levels immune response immunogenicity majority male marker median MOST occurred offered Older outcome participant positive presenting primary analysis protective immunity quantitative assessment reactogenicity recruited responses SARS-CoV-2 secondary single-center Spike protein subject suppressed T-cell T-cell Response vaccination Viremia virus-specific T-cell response white Wilcoxon signed-rank test with HIV [DOI] 10.1186/s12879-022-07737-0 PMC 바로가기
SARS CoV- 2 vaccination induces antibodies against cardiolipinArticle Published on 2022-09-072022-11-15 Journal: BMC Research Notes [Category] SARS, 진단, [키워드] administration antibody BNT162b2 ChAdOx1-S clinically Coagulopathies Concentration controls COVID-19 COVID-19 negative different time point ELISA evaluate evaluated group highest IgG antibody individual individuals induce Oxford-AstraZeneca pathogenic Pfizer positive positive individual raised reported risk Sample SARS CoV SARS-COV-2 infection SARS-CoV-2 vaccines second dose serum significant difference the vaccine thrombosis vaccination venous was measured [DOI] 10.1186/s13104-022-06180-3 PMC 바로가기
IL27 gene expression distinguishes multisystem inflammatory syndrome in children from febrile illness in a South African cohortArticle Published on 2022-09-062022-11-15 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 치료제, [키워드] African Anti-inflammatory Antiviral change children clinically Cohort condition conditions Control controls COVID-19 cytokine differential expression differentially expressed gene down-regulated gene expression febrile febrile illness Follow-up Gene Expression healthy healthy children healthy controls highlight IL-27 IL27 immune gene immune-related gene Inflammatory inflammatory condition inflammatory conditions inflammatory reaction innate immune pathway innate immune system investigated Kawasaki disease lack longitudinal MIS-C Multisystem inflammatory syndrome Other pathway Patient pyroptosis quantitative PCR resolved SARS-CoV-2 SARS-COV-2 infection Sensitivity and specificity South South Africa specimen syndrome systemic lupus erythematosus timepoints Treatment two group unique up-regulated was determined [DOI] 10.3389/fimmu.2022.992022 PMC 바로가기
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy)Article Published on 2022-09-042022-11-15 Journal: Journal of Translational Medicine [Category] 바이오마커, 유전자 메커니즘, [키워드] Accuracy addition adjuvant advance adverse events Algorithm anti-CTLA-4 Anti-PD-1 approach approved Biomarker Biomarkers biopsy BRAF BRAF inhibitor bridge cancers Cell characterized Chemotherapy clinically Combination Combination strategies combination therapy combination treatment COVID-19 pandemic development Diagnosis Drug administration Efficacy effort Evidence feature genomic help Host immune response immune Immune checkpoint inhibitor immune response Immunotherapy improve diagnostics Improved Italy lesions management mechanism mechanism of action MEK inhibitor Melanoma Naples Neoadjuvant oncogenic overcome Patient patients platform Precision predict Predictive Radiotherapy Research robust specific treatment survival systemic and local target target therapy tested therapeutic therapeutic agent therapy translational treatment regimens tumor immunity tumor microenvironment Vaccine viruses [DOI] 10.1186/s12967-022-03592-4 PMC 바로가기
Psychosis during the COVID-19 pandemic: A systematic review of case reports and case seriesReview article Published on 2022-09-012022-10-05 Journal: Journal of psychiatric research [Category] 진단, [키워드] age And schizophrenia articles Case report Case series case sery clinical history clinically complications Coronavirus disease 2019 Course COVID-19 COVID-19 infection COVID-19 patient COVID-19-related symptoms database demographic characteristics died disease disorder dose eligibility criteria evaluate evaluated Follow-up had no Hallucination highlight management men Mild moderate Most patient Occurrence Paranoia Patient patients with COVID-19 presenting Prognosis Psychiatric Psychiatric disorders Psychosis Psychotic delusion reported resolved Result SARS-CoV-2 searched severe acute respiratory syndrome coronavirus 2 significantly subset Symptom Symptoms systematic review the patient treated Treatment unique women [DOI] 10.1016/j.jpsychires.2022.06.041 [Article Type] Review article
Patient-centered outcomes at hospital discharge in mechanically ventilated COVID-19 patients in Kobe, Japan: A single-center retrospective cohort studyResearch article Published on 2022-09-012022-10-05 Journal: Respiratory investigation [Category] 변종, [키워드] Activities of Daily Living adult COVID-19 patient clinical clinically Comorbidity conducted coronavirus disease COVID-19 COVID-19 infection COVID-19 patient Critical care demonstrated died discharge Dyspnea functional hospital discharge Hospitalization ICU in-hospital mortality independent intensive care interquartile range invasive Japan Kobe mechanical ventilation mechanically ventilated median age on mechanical ventilation organ dysfunction organ function outcome Patient receiving required Respiratory Support respiratory symptoms Result retrospective cohort study Retrospective study single-center survived survivor Survivors the patient was related [DOI] 10.1016/j.resinv.2022.06.010 [Article Type] Research article
Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in GermanyArticle Published on 2022-09-012022-11-15 Journal: JAMA Network Open [Category] SARS, 진단, [키워드] 95% CI adjusted Adolescent age association blood draws children chronic chronic fatigue syndrome clinical information clinically collected complex containment measures contribute COVID-19 pandemic COVID-19 symptom cross-sectional disease Encephalomyelitis enzyme-linked immunosorbent assays Epidemiological study estimate evaluated Extensive fatigue female Germany hospital indicated joint lockdown male median age mental health outcome Pain parental participant Patient pediatric physical Quality of life questionnaire recruited reduction in reported risk SARS-CoV-2 SARS-CoV-2 IgG antibody SARS-COV-2 infection SARS-CoV-2 seroprevalence Seropositivity serum sample Sex Symptom Symptoms was determined was performed [DOI] 10.1001/jamanetworkopen.2022.33454 PMC 바로가기
Depression Among Portuguese Pregnant Women During Covid-19 Lockdown: A Cross Sectional StudyCovid-19 잠금 기간 동안 포르투갈 임산부의 우울증: 단면 연구Article Published on 2022-09-012022-09-11 Journal: Maternal and child health journal [Category] COVID19(2023년), SARS, 치료기술, [키워드] affecting age approved association Characteristics clinically coronavirus disease Coronavirus disease 2019 COVID COVID-19 criteria cross-sectional cross-sectional study Declaration of Helsinki demonstrated Depression depressive symptom Depressive symptoms during pregnancy Early detection Effect eligibility criteria enrolled ethical standard ethical standards evaluate Helsinki Intervention IRB lockdown medical history mental health issue mental health issues pandemic performed Perinatal Portugal Pregnancy Pregnancy, depression. pregnant women Primary outcome Psychiatric Psychological questionnaire regression analysis risk significant increase socio-demographic Stress Support Surveillance symptoms of depression woman women [DOI] 10.1007/s10995-022-03466-7 PMC 바로가기 [Article Type] Article
A rapid RT-LAMP SARS-CoV-2 screening assay for collapsing asymptomatic COVID-19 transmissionArticle Published on 2022-09-012022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, 치료제, [키워드] 48 hours assays Asymptomatic Asymptomatic COVID-19 clinically Collapsing diagnostic genomic individual Laboratory testing National NHS nine participant positive processed reducing reported RT-LAMP RT-PCR SARS-CoV-2 sensitivity sequence specificity subsequent supported swab sample Symptom Transmission transmission of SARS-CoV-2 Trust university utility validation was determined [DOI] 10.1371/journal.pone.0273912 PMC 바로가기
Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19Randomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] administration adverse event antibody Casirivimab clinically conducted COVID-19 death defined demonstrated development dose doses double-blind Efficacy end point evaluate evaluated exploratory hypersensitivity reaction Imdevimab incidence of COVID-19 laboratory-confirmed monoclonal antibody occurred Occurrence occurrence of COVID-19 Odds ratio participant Placebo placebo-controlled trial Prevent proportion Randomized reaction reduction in Repeat reported risk reduction SARS-CoV-2 Seroconversion substantial risk Tolerability treatment period treatment-emergent adverse event uninfected volunteers [DOI] 10.1016/j.ijid.2022.06.045 PMC 바로가기 [Article Type] Randomized Controlled Trial