Proof of Concept for a Quick and Highly Sensitive On-Site Detection of SARS-CoV-2 by Plasmonic Optical Fibers and Molecularly Imprinted Polymers플라즈몬 광섬유 및 분자 각인 폴리머에 의한 SARS-CoV-2의 빠르고 고감도 현장 탐지를 위한 개념 증명Article Published on 2021-03-012022-09-10 Journal: Sensors (Basel, Switzerland) [Category] SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus Analysis caused chain Chain Reaction concept coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated detection diagnostic diagnostics Effectiveness equipment fiber international public health layer medium MIP molecularly imprinted polymers (MIPs) NaCl nasopharyngeal optical Optical fiber optical fiber sensors optical-chemical sensors pandemic pathogen performed physiological solution point-of-care Polymer polymerase chain reaction proof proof of concept Protein reaction reagent reagents real time receptor respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 virions SARS-CoV-2 virus sensitive sensitivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spike protein Spread subunit surface plasmon resonance (SPR) Swab tested the SARS-CoV-2 the SARS-CoV-2 virus Transport transport medium Universal Transport Medium UTM virus was obtained [DOI] 10.3390/s21051681 PMC 바로가기 [Article Type] Article
COVID-19 Thrombosis: Bridging the Old and New ConceptsReview Article Published on 2021-02-242022-10-30 Journal: The Malaysian Journal of Medical Sciences : MJMS [Category] COVID-19, [키워드] absence approach autopsy study Bridging combating concept coronavirus disease COVID-19 COVID-19 patient Cytokines Endothelial dysfunction hypercoagulable imperative Inflammation Microvascular thrombosis New pandemic Pathogenesis suggested therapeutic thrombosis thrombus formation Treatment Vaccines [DOI] 10.21315/mjms2021.28.1.2 PMC 바로가기 [Article Type] Review Article
Platelet Lysate Nebulization Protocol for the Treatment of COVID-19 and Its Sequels: Proof of Concept and Scientific RationaleCOVID-19 및 그 후속작의 치료를 위한 혈소판 용해물 분무 프로토콜: 개념 증명 및 과학적 근거Article Published on 2021-02-122022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, 진단, [키워드] absence acting acute respiratory distress acute respiratory distress syndrome administration Anti-inflammatory antifibrotic biological activity cell cultures clinical trials concept coronavirus disease Coronavirus disease 2019 COVID-19 Defense Effect effective Effects evaluate fibroblast growth factor Growth factors healthy donor healthy donors help immunomodulatory Inflammation lung lung disorder lung disorders Lung function lung tissue lysate modulating molecular nebulization nebulized pathology Platelet platelet lysate platelet-rich plasma Platelets proof protocol rationale respiratory respiratory disorder respiratory disorders respiratory distress resulting Structure syndrome the disease the patient therapeutic targets therapy Viral viral infections virus viruses [DOI] 10.3390/ijms22041856 PMC 바로가기 [Article Type] Article
Pilot Production of SARS-CoV-2 Related Proteins in Plants: A Proof of Concept for Rapid Repurposing of Indoor Farms Into Biomanufacturing FacilitiesPlant Science Published on 2020-12-232022-10-31 Journal: Frontiers in Plant Science [Category] COVID-19, [키워드] anti-SARS-CoV-2 antibody antibodies benthamiana binding biofactories concept COVID-19 Critical develop diagnostic reagent DNA sequence expressed facility farm fused group Health information lab Local mAb mAbs molecular farming monoclonal antibody Nicotiana benthamiana plant-made antibody plant-made antigen platform positive produced Production proof Protein protocol Rapid RBD Receptor binding domain repurposing respond responses SARS-CoV-2 SARS-CoV-2 N protein specificity tested the antibodies the Spike therapeutic Viral vector weakness [DOI] 10.3389/fpls.2020.612781 PMC 바로가기 [Article Type] Plant Science
Global Public Health Database Support to Population-Based Management of Pandemics and Global Public Health Crises, Part I: The ConceptSpecial Report Published on 2020-10-222022-10-29 Journal: Prehospital and Disaster Medicine [Category] COVID-19, MERS, SARS, [키워드] change concept coronavirus disease COVID-19 global public health Improvements information management pandemic Pandemics Part population-based management Public public health supported Triage [DOI] 10.1017/S1049023X20001351 PMC 바로가기 [Article Type] Special Report
Renin-Angiotensin System Inhibitors in COVID-19: Current ConceptsReview Article Published on 2020-10-212022-10-29 Journal: International Journal of Hypertension [Category] COVID-19, [키워드] ACE-2 Activation angiotensin-converting enzyme-2 concept contrary coronavirus disease COVID-19 COVID-19 patient current demonstrated drug Effect enzyme evaluated expression facilitate functional increase in Lung injury pandemic pathophysiological mechanism protective role RAS RAS inhibitor receptor renin-angiotensin system researcher responsible SARS-CoV-2 System Trial viral invasion virus [DOI] 10.1155/2020/1025913 PMC 바로가기 [Article Type] Review Article
Emerging Concepts and Technologies in Vaccine DevelopmentImmunology Published on 2020-09-302022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] addition addressed approach Cancer cancer vaccines caused concept COVID-19 COVID19 development disease Diseases Immunity immunology inactivated Infectious disease medical condition mitigate nanoparticle vaccines non-viral DNA-RNA vaccines noncommunicable disease offer pathogen Pathogens provide remained significantly substance abuse subunit vaccines technology vaccination Vaccine Vaccine design Vaccine development Vaccines virus-like particle vaccines [DOI] 10.3389/fimmu.2020.583077 PMC 바로가기 [Article Type] Immunology
The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary ConceptPublic Health Published on 2020-09-222022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV biochemical clinician concept Corticosteroids COVID-19 Cytokine storm develop Evaluating help Host immune response hyperimmune hyperimmune response Immunosuppressive treatment implicated Inflammation large cohort MERS response SARS-CoV-2 score scoring system severity the disease Treatment [DOI] 10.3389/fpubh.2020.550933 PMC 바로가기 [Article Type] Public Health
Impacts of COVID-19 on Electronic Cigarette Purchasing, Use and Related BehaviorsArticle Published on 2020-09-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected Analysis approach Behavior caused challenge cigarette Cluster Clusters concept COVID-19 Disruption Electronic cigarette Electronic cigarettes examined group Health Hierarchical identify Impact impacts Improving Increased less Obtaining participant Perception protection provided Purchasing Result routine Stocking Stress subgroups Tobacco unique was used [DOI] 10.3390/ijerph17186762 PMC 바로가기 [Article Type] Article
Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical ReviewReview Published on 2020-09-162022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] Angiogenesis antioxidant cellular mechanism clinical trial concept conducted contribute COVID-19 COVID-19 disease COVID-19 pandemic Critical cytokine Cytokine storm Cytokines demonstrated double blind effective Efficacy effort evaluate globe highlight immune response Inflammatory diseases Inflammatory mediators Interaction introduced low-level laser therapy modality molecular multi-organ failure New nitric oxide outcome outcomes Pathogenesis Photobiomodulation photodynamic therapy phototherapy placebo-controlled Potential treatment randomised reducing Research question review robust Safe SARS-CoV-2 SARS-CoV-2 viral infection shown Therapies Treatment Vaccine Vaccines virus [DOI] 10.3390/antiox9090875 PMC 바로가기 [Article Type] Review