Cycle Threshold Values from Severe Acute Respiratory Syndrome Coronavirus-2 Reverse Transcription-Polymerase Chain Reaction Assays: Interpretation and Potential Use Cases중증 급성 호흡기 증후군 코로나바이러스-2 역전사-중합효소 연쇄 반응 분석의 주기 임계값: 해석 및 잠재적 사용 사례Review Published on 2022-06-012022-09-11 Journal: Clinics in laboratory medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 approved Caregiver Caregivers chain Chain Reaction clinical care Concentration coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Ct value Ct values cycle cycle threshold Cycle threshold value determine Infection polymerase chain reaction Potential progression reaction reflect respiratory reverse transcription Reverse transcription-polymerase chain reaction RNA RT-PCR SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus the patient threshold value Variability Viral RNA virus [DOI] 10.1016/j.cll.2022.02.003 PMC 바로가기 [Article Type] Review
Cycle Threshold Probability Score for Immediate and Sensitive Detection of B.1.351 SARS-CoV-2 LineageArticle Published on 2022-05-042023-07-07 Journal: American journal of clinical pathology [Category] COVID19(2023년), [키워드] Cycle threshold value Data analysis modeling PCR SARS-CoV-2 Secondary data analysis. [DOI] 10.1093/ajcp/aqab186
Multiplatform Assessment of Saliva for SARS-CoV-2 Molecular Detection in Symptomatic Healthcare Personnel and Patients Presenting to the Emergency Department증상이 있는 의료 종사자 및 응급실에 내원하는 환자에서 SARS-CoV-2 분자 검출을 위한 타액의 다중 플랫폼 평가Article Published on 2022-05-042022-09-11 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assessment center clinical symptom Clinical symptoms collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cycle threshold value Department detection DiaSorin Direct Emergency emergency department enrolled evaluated healthcare personnel knowledge Lyra molecular Molecular assay molecular assays nasopharyngeal NP swab NP swabs Patient positive presenting relative sensitivity respiratory Saliva saliva sample saliva samples saliva specimen saliva specimens SARS-CoV-2 severe acute respiratory syndrome Coronavirus specimen subset swabs symptomatic These data university Variability [DOI] 10.1093/jalm/jfab115 PMC 바로가기 [Article Type] Article
A Comparison of Seegene Technologies Novaplex SARS-CoV-2 Variants I, II, and IV Assays with Spike Gene Sequencing for Detection of Known Severe Acute Respiratory Syndrome Coronavirus 2 VariantsSeegene Technologies Novaplex SARS-CoV-2 변이 I, II 및 IV 분석과 알려진 중증 급성 호흡기 증후군 코로나바이러스 2 변이의 검출을 위한 스파이크 유전자 시퀀싱의 비교Article Published on 2022-05-012022-09-11 Journal: The Journal of molecular diagnostics : JMD [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Concentration coronavirus coronavirus 2 cycle threshold Cycle threshold value detect detection disease severity extracted RNA extraction extraction-free method gold gold standard I, II in some increasingly labor-intensive less Mutation nucleic acid protocol Public health responses respiratory RNA RNA extraction Sanger sequencing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing spike spike gene Surveillance technology Transmission Treatment variant variants variants of interest were assessed [DOI] 10.1016/j.jmoldx.2022.02.001 PMC 바로가기 [Article Type] Article
SARS-CoV-2 viral load and replication in postmortem examinations사후 검사에서 SARS-CoV-2 바이러스 부하 및 복제Article Published on 2022-05-012022-09-11 Journal: International Journal of Legal Medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] age Autopsy Chain Reaction clinical Clinical autopsy Compliance COVID-19 criteria Cycle threshold value death deaths died examined Forensic Forensic autopsy Hospitalization Hospitalized infected case infected cases investigated lung mRNA nasopharyngeal Older p value performed positive postmortem examination Registered Replication replicative reverse transcriptase SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral load statistically significant Swab tested the mean Viral load viral replication was performed [DOI] 10.1007/s00414-021-02753-2 PMC 바로가기 [Article Type] Article
Analysis of clinical characteristics of 66 pediatric patients with B.1.617.2 (Delta) variant of COVID-19COVID-19의 B.1.617.2(델타) 변이형 소아 환자 66명의 임상적 특성 분석Article Published on 2022-05-012022-09-11 Journal: World Journal of Pediatrics [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] 24 hour 24 hours accumulate acute respiratory syndrome acute respiratory syndrome coronavirus Admission age All the patient all the patients Analysis analyzed antibody B.1.617.2 B.1.617.2 (Delta) cardiac troponin Cardiac troponin I Characteristics children children with COVID-19 clinical Clinical characteristics clinical experience Clinical features clinical symptom Clinical symptoms Cluster coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Cycle threshold value Cycle threshold values D-dimer Delta description disease onset erythrocyte sedimentation erythrocyte sedimentation rate evaluate Frame Gender Genome gradually increased group help hospital IgG IgM IgM antibodies IgM antibody Immunoglobulin Incubation period laboratory data medical staff Mild moderate nucleocapsid protein Open reading frame open reading frame 1 Pediatric patient positive respiratory sedimentation rate severe acute respiratory syndrome Coronavirus statistically significant difference Symptom tested titers troponin I variant [DOI] 10.1007/s12519-022-00529-1 PMC 바로가기 [Article Type] Article
Factors associated with cycle threshold values (Ct-values) of SARS-CoV2-rRT-PCRSARS-CoV 2-rT-PCR의 주기 역치 값(Ct 값)과 관련된 요인Article Published on 2022-05-012022-09-11 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] age association Care caution clinical clinical history COVID-19 COVID-19 severity COVID-19 testing Ct values Ct-values cycle cycle threshold Cycle threshold value Cycle threshold values demographics diagnostic distribution distributions examined Factor Health Health care individual information limitation N gene ORF1ab Patient PCR assays PCR test RdRP RdRp gene RdRp genes reported RT-PCR assay RT-PCR assays RT-PCR test SARS-CoV-2 SARS-CoV-2 positive patient SARS-CoV-2 positive patients SARS-CoV-2 RT-PCR test Sex Symptom Symptomatology the patient the SARS-CoV-2 threshold was collected [DOI] 10.1007/s11033-022-07360-x PMC 바로가기 [Article Type] Article
Cross-sectional cycle threshold values reflect epidemic dynamics of COVID-19 in MadagascarResearch article Published on 2022-03-012022-10-05 Journal: Epidemics [Category] SARS, 바이오마커, [키워드] Africa approach Biomarker can be used Course COVID-19 cross-sectional Cross-sectional data cycle threshold Cycle threshold value distribution Epidemic epidemic wave epidemiological estimate extension febrile illness growth growth rate incidence Infection Laboratory Laboratory testing LMIC madagascar National offer platform processed real time Region regions resource RT-qPCR SEIR statistically significant Surveillance trajectory viral kinetics Viral load [DOI] 10.1016/j.epidem.2021.100533 [Article Type] Research article
Performance evaluation of Elecsys SARS-CoV-2 Antigen immunoassay for diagnostic of COVID-19코로나19 진단을 위한 Elecsys SARS-CoV-2 항원 면역분석의 성능 평가Article Published on 2022-03-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aims alternative Antigen antigen detection antigen tests Chain Reaction complement coronavirus COVID-19 cross Cross reactivity cross-reactivity Cycle threshold value diagnostic Elecsy Elecsys evaluate HKU1 identify immunoassay individual Infection Influenza Influenza virus Nasopharyngeal swab nasopharyngeal swabs Negative predictive value NPV OC43 other respiratory virus Other respiratory viruses parainfluenza virus performance point of care polymerase chain reaction positive PPV Predictive value Randomly ranged reduce reference test respiratory viruses reverse transcription Reverse transcription-polymerase chain reaction rhinovirus Roche Diagnostics RT-PCR RT-PCR testing SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigen tests SARS-CoV-2 transmission selected sensitivity severe acute respiratory syndrome Coronavirus specificity STAT Symptoms [DOI] 10.1002/jmv.27412 PMC 바로가기 [Article Type] Article
Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta VariantsmRNA COVID-19 백신 3회 용량과 SARS-CoV-2 오미크론 및 델타 변이체로 인한 증상 감염 간의 연관성Observational Study Published on 2022-02-152022-09-11 Journal: JAMA [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI adjusted odds ratio age Analysis Assessing association Before test BNT162b2 booster dose Case-control Control controls COVID-19 COVID-19 testing COVID-19 vaccine Critical Cycle threshold value defined Delta delta variant Delta variants dose doses eligible Guidance health guidance higher odd individual less median Moderna mRNA-1273 vaccine mRNA mRNA vaccine multinomial regression multivariable National nucleic acid Odds ratio Older omicron ORF1ab outcome Pfizer Pfizer-BioNTech public health receipt reported S-gene SARS-CoV-2 SARS-COV-2 infection second dose secondary outcome seeking significantly higher stratified symptomatic SARS-CoV-2 infection tested the SARS-CoV-2 vaccination Vaccination Status vaccine dose variant variants viral genes were measured women [DOI] 10.1001/jama.2022.0470 PMC 바로가기 [Article Type] Observational Study