Lung Ultrasound Patterns and Clinical-Laboratory Correlates during COVID-19 Pneumonia: A Retrospective Study from North East ItalyArticle Published on 2021-03-202022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age Analysis B-lines case sery clinical parameter consolidation consolidations Coronavirus disease-19 correlated COVID-19 COVID-19 severity disease disease severity disease stage East end-organ damage examined High-flow oxygen hospital Inflammation inflammatory biomarkers Italy lung lung field Lung ultrasound medications men North Older onset of symptoms operators outcomes pathophysiological Patient patients patients with COVID-19 pattern performed Pneumonia recorded repeated retrospective SARS-COV-2 infection scored severity significantly tissue Ultrasound was performed while [DOI] 10.3390/jcm10061288 PMC 바로가기 [Article Type] Article
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19TLR 신호 전달에 대한 하이드록시클로로퀸 효과: 노출 부족이지만 COVID-19에서 무시할 수 없음Review Published on 2021-03-092022-09-10 Journal: Journal of Immunology Research [Category] SARS, 치료제, [키워드] balance Clinical data Clinical effect COVID-19 dependent on disease severity disease stage Effect Evidence HCQ Hydroxychloroquine Immunity Immunosuppression in vitro inhibit initial Interference outcome Prophylactic Randomized SARS-CoV-2 Side effects Stage supported suppresse target the disease therapeutic TLR Treatment treatment for COVID-19 Viral viral replication [DOI] 10.1155/2021/6659410 PMC 바로가기 [Article Type] Review
Different characteristics of critical COVID-19 and thinking of treatment strategies in non-elderly and elderly severe adult patientsResearch article Published on 2021-03-012022-10-05 Journal: International immunopharmacology [Category] SARS, 치료법, [키워드] Admission cause Characteristics clinical Corticosteroid COVID-19 COVID-19 infection Critical critical COVID-19 disease disease stage elderly patients Factor fluctuation High-sensitivity C-reactive protein Hospitalization hsCRP hsCRP fluctuation ICU ICU admission independent risk factor inflammatory markers Inflammatory response inflammatory state intensive care neutrophil outcome parameter Patient patients Predictive recommendations renal Result risk factor severe COVID-19 severe COVID-19 patients Severe patient severe patients therapy Tongji Hospital Treatment treatment strategy Wuhan, China Young and middle-aged patients [DOI] 10.1016/j.intimp.2020.107343 [Article Type] Research article
The pulmonary pathology of COVID-19Review and Perspectives Published on 2021-02-192022-10-29 Journal: Virchows Archiv [Category] COVID-19, MERS, [키워드] affected Angiogenesis Autopsies Autopsy caused change characterized COVID-19 cytokine level D-dimer DAD death decrease described Diffuse alveolar damage disease stage disease stages disorder edema elevated epithelial fatal COVID-19 feature Features Frequency group hyaline membrane formation hypercoagulability lung lung damage Lung pathology lymphopenia majority massive secretion novel coronavirus SARS-CoV-2 organ pathophysiology Patient patients pro-inflammatory cytokine pulmonary disease Pulmonary pathology question SARS-CoV-2 severe coronavirus disease severe COVID-19 Thromboembolic events thrombotic tissue repair viral infections Viral load virus load [DOI] 10.1007/s00428-021-03053-1 PMC 바로가기 [Article Type] Review and Perspectives
Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and MortalityObservational Study Published on 2021-02-112022-10-05 Journal: American journal of clinical pathology [Category] 임상, [키워드] 25(OH)D 95% CI 95% confidence interval acute respiratory syndrome Admission age association Chest computed tomography Chest CT Comorbidities coronavirus coronavirus disease correlated COVID-19 COVID-19 disease deficiency diabete disease stage expressed female Hospitalized incidence independent individual investigated Laboratory analysis Level lung damage Lung disease male males Mortality multivariate regression analysis Odds ratio outcome patients with COVID-19 Pneumonia radiologic retrospective SARS-CoV-2 serum 25-hydroxyvitamin D severity Stage survival the patient Trial Viral pneumonia Vitamin D vitamin D deficiency was done was performed with COVID-19 [DOI] 10.1093/ajcp/aqaa252 PMC 바로가기 [Article Type] Observational Study
Observational cohort study of IP-10’s potential as a biomarker to aid in inflammation regulation within a clinical decision support protocol for patients with severe COVID-19심각한 COVID-19 환자를 위한 임상 의사 결정 지원 프로토콜 내에서 염증 조절을 돕는 바이오마커로서의 IP-10의 잠재력에 대한 관찰 코호트 연구Clinical Trial Published on 2021-01-122022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, 바이오마커, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Admission Biomarker clinical decision cohort study coronavirus correlated Corticosteroid corticosteroid immunomodulatory therapy COVID-19 patient COVID-19 patients COVID-19-related complications died disease stage disease stages host protein host-pathogen interaction hyperinflammation immune immunoassay immunomodulatory therapy Inflammation intensive care intensive care unit interferon involved IP-10 Lung injury management Mortality Oxygenation Patient performed platform protocol quantitative measurement Registered Regulation respiratory Result severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 severely ill COVID-19 patients Severity Score significantly single-center subsequent Support therapeutic utility Viral viral clearance virus-induced hyperinflammation while with COVID-19 γ-induced protein 10 [DOI] 10.1371/journal.pone.0245296 PMC 바로가기 [Article Type] Clinical Trial
The art of the possible in approaching efficacy trials for COVID19 convalescent plasmaCOVID19 회복기 혈장에 대한 효능 시험에 접근하는 가능성의 기술Article Published on 2021-01-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 임상, [키워드] biases CCP clinical trial control arm convalescent plasma COVID-19 COVID19 disease stage dose Efficacy Evidence outcome measures randomized clinical trial Randomized controlled trial Randomized controlled trials RCT RCTs specification therapeutic therapeutic dose Treatment Trial while [DOI] 10.1016/j.ijid.2020.10.074 PMC 바로가기 [Article Type] Article
The Need for Antiviral Drugs for Pandemic Coronaviruses From a Global Health PerspectiveMedicine Published on 2020-12-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Administered Antiviral antiviral drugs antiviral therapy caused clinical study clinical trial conserved coronavirus Coronaviruses COVID-19 COVID-19 pandemic creating Dexamethasone disease stage drug Drug discovery drugs early treatment effective global health hospital hospitalized patients Infection influenza viruses Interaction investigated majority Mortality outbreak preparedness pandemic pharmacotherapy Prevent recovery Remdesivir respiratory respiratory viral infection respiratory virus SARS-CoV-2 solidarity Stage symptom duration target product profile the disease the United State Treatment viral dynamics Viral load Viral pneumonia Viral protein widespread [DOI] 10.3389/fmed.2020.596587 PMC 바로가기 [Article Type] Medicine
Fears and Perception of the Impact of COVID-19 on Patients With Lung Cancer: A Mono-Institutional SurveyOncology Published on 2020-10-142022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] addition Administered age Cancer cancer diagnosis Cancer patients changes in Comorbidity Contagion Coronavirus disease 2019 country COVID-19 COVID-19 symptoms disease disease stage division fear Fears Government highlight hospital Impact intravenous Italian Italy lockdown lung lung cancer lung cancer patient Measures pandemic Patient patient’s perception patients with comorbidity Perception Quality of life quarantine Radiotherapy reduce risk Sex survey the patient the SARS-CoV-2 Treatment women worsened [DOI] 10.3389/fonc.2020.584612 PMC 바로가기 [Article Type] Oncology
In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19병원 내 사망률은 COVID-19로 입원한 NAFLD 환자의 염증 반응과 관련이 있습니다Research Article Published on 2020-10-082022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Admission adverse outcomes C reactive protein cirrhosis clinical Clinical characteristics Clinical data Clinical endpoints clinical outcomes Cohort college consecutive patient COVID-19 CRP Diagnosis died discharged disease disease stage early weaning score Endpoint Evidence EWS Fatty liver fatty liver disease ferritin FIB-4 fibrosis Fibrosis-4 Gender hospital hospitalised Imperial College Healthcare NHS Trust in-hospital mortality Inflammatory response intensive care intensive care unit liver Liver cirrhosis male medical history metabolic risk factor metabolic risk factors Mortality NAFLD NAFLD patient NAFLD patients NHS nine Non-alcoholic fatty liver disease non-NAFLD on admission outcome past medical history Patient Result risk severe COVID-19 significantly stratified Trust were recorded [DOI] 10.1371/journal.pone.0240400 PMC 바로가기 [Article Type] Research Article