PynA is a pyrimidine 5′-nucleotidase that functions as an antimutator protein in Streptococcus pneumoniaearticle Published on 2020-01-312024-09-01 Journal: The FEBS Journal [Category] 폐렴구균 감염증, [키워드] antimutator protein DNA repair house-cleaning enzyme pyrimidine 5′-nucleotidase Streptococcus pneumoniae [Article Type] article
Infection with genotoxin‐producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells유전자 독소를 생성하는 Salmonella enterica 감염은 대장 상피 세포에서 PI3K 경로를 통해 유전체 불안정을 촉진하는 종양 억제 인자 APC의 손실과 시너지 효과를 냅니다.Research Article Published on 2019-08-262024-08-19 Journal: Cellular Microbiology [Category] 살모넬라증, [키워드] APC bacteria and cancer bacterial genotoxin DNA damage response DNA repair organotypic model tumour‐suppressor gene [DOI] 10.1111/cmi.13099 PMC 바로가기 [Article Type] Research Article
Heteroexpression of Mycobacterium leprae hypothetical protein ML0190 provides protection against DNA-alkylating agent methyl methanesulfonate마이코박테리움 레프라이 가설 단백질 ML0190의 이종 발현은 DNA 알킬화제인 메틸 메탄설포네이트에 대한 보호를 제공합니다.Article Published on 2019-02-122024-08-24 Journal: Biochemical and Biophysical Research Communications [Category] 한센병, [키워드] AlkB Alkylation dioxygenase DNA repair ML0190 Mycobacterium leprae
A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation—and Beyond?Review Published on 2017-05-222023-06-02 Journal: Viruses [Category] B형 간염, [키워드] cccDNA DNA damage response DNA repair HBV cure HBV minichromosome Hepatitis B virus [DOI] 10.3390/v9050125 PMC 바로가기 [Article Type] Review
Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data게놈 전체 일배체형 데이터에서 인간의 후보 생식계열 돌연변이 유전자좌의 추론Research Article Published on 2017-01-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 1000 Genome 1000 Genomes 1000 Genomes Project affected allele alleles base bases BRSK2 candidate Cell characterized cohorts de novo mutation de novo mutations DNA damage DNA repair elevated error expressed genetic loci Genetic variation Genome genome sequence genomic region germline Haplotype haplotypes Human human diseases Human genomes human population human populations identify incorporation increase individual Inference involved lead loci locus Mutation mutation rate Netherland occur offspring parent parents Phase 3 proportion remained replicated reported resulting searched species spontaneous mutations Support Testis thought upstream Variation [DOI] 10.1371/journal.pgen.1006549 PMC 바로가기 [Article Type] Research Article
Genomic survey and expression analysis of DNA repair genes in the genus LeptospiraArticle Published on 2016-04-012023-06-03 Journal: Molecular genetics and genomics : MGG [Category] 조류인플루엔자, [키워드] Bacterial genomics DNA repair Leptospira Mutagenesis SOS response. [DOI] 10.1007/s00438-015-1135-2
Intracellular Mono-ADP-Ribosylation in Signaling and DiseaseReview Published on 2015-09-252023-08-30 Journal: Cells [Category] E형 간염, [키워드] ADP-ribosylation Cancer DNA repair Endoplasmic reticulum gene transcription Immunity Infection NF-κB Signaling Stress [DOI] 10.3390/cells4040569 PMC 바로가기 [Article Type] Review
Emerging importance of mismatch repair components including UvrD helicase and their cross-talk with the development of drug resistance in malaria parasitearticle Published on 2014-12-312024-09-01 Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis [Category] 말라리아, [키워드] DNA repair drug resistance Mismatch repair Plasmodium falciparum UvrD [Article Type] article
SARS coronavirus protein 7a interacts with human Ap 4 A-hydrolaseResearch Published on 2010-02-092022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] activated Activation Amino acid Apoptosis cell proliferation cellular co-immunoprecipitation culture cell cytoplasm DNA repair DNA replication ENCODE expressing Frame Host Human human cell interact Interaction involved nucleotide ORF pathogenic processe Protein protein synthesis Proteins Regulation responsible RNA SARS Coronavirus SARS-CoV sequence homology shown tissue virus yeast [DOI] 10.1186/1743-422X-7-31 PMC 바로가기 [Article Type] Research