Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2Article Published on 2020-11-062023-07-11 Journal: The Journal of Biological Chemistry [Category] SARS, [키워드] ACE2 epithelium human nasal epithelial cells Infection Infectious disease Nasal Epithelial cells receptor SARS–CoV-2 sphingolipid sphingosine spike virus entry [DOI] 10.1074/jbc.RA120.015249 PMC 바로가기
Long-Term Modeling of SARS-CoV-2 Infection of In Vitro Cultured Polarized Human Airway EpitheliumResearch Article Published on 2020-11-062022-10-29 Journal: mBio [Category] COVID-19, SARS, [키워드] acute respiratory syndrome airway airway epithelia airway epithelial damage airway epithelium Basal cell basolateral side cause caused characterized ciliated ciliated cell club cell Club cells confirmed case contribute coronavirus coronavirus disease COVID-19 COVID-19 patients Culture damaged demonstrated dominant donors epithelial epithelial cell epithelial damage epithelium exhibit expression fatality Goblet cell goblet cells HAE highlight Human human airway epithelia Human airway epithelium human airways in vitro in vitro model in vivo independent infect Infection infections initiate long-lasting long-term infection lung maintain mimicking modeling pandemic progeny proliferation recurrent infection replicate Replication replication of SARS-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 propagation SARS-CoV-2 replication Support tested the SARS-CoV-2 tight junction Viral load virion virus virus infection virus replication ZO-1 [DOI] 10.1128/mBio.02852-20 PMC 바로가기 [Article Type] Research Article
Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung EpitheliumCommunication Published on 2020-08-262022-10-31 Journal: Genes [Category] COVID-19, [키워드] acute respiratory syndrome binding site cellular cellular antiviral defence coronavirus coronavirus disease Coronavirus infection COVID-19 differentially expressed epithelium Evidence expression expression profile Genome Human identify In vitro infection Infection infections low expression lung epithelia lung epithelial mechanism MERS-CoV genome microRNA pandemic pathogenic coronavirus predicted prediction PROTECT Research responsible RNA virus RNA viruses SARS-CoV SARS-CoV-2 susceptibility the SARS-CoV-2 genome tissue viral propagation [DOI] 10.3390/genes11091002 PMC 바로가기 [Article Type] Communication
Host–Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway ModelArticle Published on 2020-06-242023-06-07 Journal: Viruses [Category] 신종인플루엔자, [키워드] Antiviral cell death chemokine cytokine cytoskeleton epithelium Inflammation innate immune system lung tight junction [DOI] 10.3390/v12060679 PMC 바로가기 [Article Type] Article
Growing and Characterizing Biofilms Formed by Streptococcus pneumoniaearticle Published on 2019-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 폐렴구균 감염증, [키워드] biofilm carriage colonization competence dispersion epithelium mucosa nasopharynx respiratory tract Streptococcus pneumoniae transformation virulence [Article Type] article
In Vitro and In Vivo Biofilm Formation by Pathogenic Streptococciarticle Published on 2017-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 폐렴구균 감염증, [키워드] biofilm colonization epithelium mucosa nasopharynx respiratory tract streptococci Streptococcus pneumoniae virulence [Article Type] article
Salmonella Typhimurium Diarrhea Reveals Basic Principles of Enteropathogen Infection and Disease-Promoted DNA Exchange살모넬라 타이피무리움 설사는 장병원체 감염 및 질병 촉진 DNA 교환의 기본 원리를 드러낸다.Article Published on 2017-04-122024-08-21 Journal: Cell Host & Microbe [Category] 살모넬라증, [키워드] antibody epithelium Inflammasome Inflammation microbiota mucosa NLRC4 phage Plasmid secretory IgA
Human Milk Hyaluronan Enhances Innate Defense of the Intestinal Epithelium인간의 유당 히알루론산은 장 상피의 선천적 방어 기능을 향상시킵니다.journal-article Published on 2013-10-012024-07-31 Journal: Brain stimulation [Category] 살모넬라증, [키워드] CD44 Defensins epithelium host defense human milk Hyaluronate Salmonella infection toll-like receptors (TLR) [DOI] 10.1074/jbc.M113.468629 [Article Type] journal-article
Cellular and subbasal nerve alterations in early stage Fuchs’ endothelial corneal dystrophy: an in vivo confocal microscopy studyClinical Study Published on 2013-01-162024-09-04 Journal: Eye (London, England) [Category] 대상포진, [키워드] Cornea Corneal nerves epithelium Fuchs' endothelial corneal dystrophy in vivo confocal microscopy keratocytes [DOI] 10.1038/eye.2012.220 PMC 바로가기 [Article Type] Clinical Study
MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic StressMK2-의존성 p38b 신호는 만성 스트레스 하에서 JNK 유도 세포자멸사로부터 Drosophila Hindgut Enterocytes를 보호합니다Research Article Published on 2011-08-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence addressed affected antimicrobial peptides Apoptosis atrophy Author branch cascade Cell chronic complex component contribute damage damaged descendants Deterioration Diseases Drosophila Elimination Enterocyte enterocytes epithelial epithelium event form genetic analysis Gut Hindgut homeostasis Impaired induce integrity intestinal Intestinal diseases intestinal epithelium intestinal stem cell Intestinal stem cells JNK kinases leads less manifested pathogen Pathogens pathway peptides peptides) Prevent proliferation PROTECT Protective Protein protein kinase replaced REPLACED BY Replenishment required salt Signal transduction stem cell stem cells Stress Stressor stressors subsequent suppresse Trigger triggers upregulated upstream [DOI] 10.1371/journal.pgen.1002168 PMC 바로가기 [Article Type] Research Article