Time series analysis of the incidence of acute upper respiratory tract infections, COVID-19 and the use of antibiotics in Finland during the COVID-19 epidemic: a cohort study of 833 444 patientsCOVID-19 전염병 동안 핀란드에서 급성 상기도 감염, COVID-19 및 항생제 사용의 발생률에 대한 시계열 분석: 833,444명의 환자를 대상으로 한 코호트 연구Article Published on 2022-01-312022-09-12 Journal: BMJ Open [Category] SARS, 진단, [키워드] Analysis Antibiotics average Care Cohort cohort study COVID-19 COVID-19 case COVID-19 epidemic COVID-19 patient declined diagnose diagnosed diagnostics Epidemiology evaluate expected Finn frequencies Google Health Service healthcare Healthcare professional help incidence increase in indicated Infection infections Isolation measure medical record medical service mild symptoms number outcome Patient prescription rapid increase reduced respiratory infections Spread the disease the epidemic time took place trajectory upper respiratory tract urinary tract infections URTIs use of antibiotics Variation [DOI] 10.1136/bmjopen-2020-046490 PMC 바로가기 [Article Type] Article
Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous SystemsReview Published on 2022-01-202022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] “long hauler” syndrome Acute heart failure affected affecting Anxiety Arrhythmias Brain cardiovascular Cardiovascular events Care clinical manifestations clinician complex Concentration coughing COVID COVID-19 Depression described develop Diseases Effect fluctuations frequencies headache heterogeneous Involvement lack less Long COVID long-term COVID-19 lung management memory Mental mental health issue myocarditis nervous neurological manifestations pandemic Patient Post-COVID-19 syndrome reported respiratory respiratory manifestation SARS-COV-2 infection Sequelae Shortness of breath sleep disorder suggested Support Symptom Symptoms syndrome System Treatment venous thromboembolic [DOI] 10.3390/jcm11030524 PMC 바로가기 [Article Type] Review
Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials A Systematic Review and Meta-analysisCOVID-19 백신 시험의 위약군에서 이상 반응 빈도 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-01-182022-09-10 Journal: JAMA Network Open [Category] SARS, 치료제, [키워드] 95% CI 95% CIs accounted Adverse adverse event adverse events AEs analyzed Arm ARMS article clinical trial clinical trials Controlled controlled trials COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccine trial COVID-19 vaccine trials COVID-19 vaccines data extraction database dose drug trials eligibility evaluate event Evidence extraction fatigue finding first dose frequencies Frequency groups headache Importance independent injection investigated item Local measure meta-analyses Meta-analysis objective Odds ratio Older participant performed Placebo placebo group placebo recipient placebo recipients placebo treatment Point Primary outcome Primary outcomes PRISMA proportion proportions provided Public Random-effects models Randomized reason reason for recipient recipients Relevance reported Reporting response Result review searched second dose selected Selection significantly more Source standardized mean difference synthesis systematic review systematic reviews systemic AE systemic AEs tested the placebo group the vaccine Trial trial participants vaccination Vaccine vaccine group vaccine trial [DOI] 10.1001/jamanetworkopen.2021.43955 PMC 바로가기 [Article Type] Meta-Analysis
Prioritizing high-contact occupations raises effectiveness of vaccination campaignsArticle Published on 2022-01-142022-10-04 Journal: Scientific Reports [Category] 변종, [키워드] Contact disease effective Effectiveness Efficiency Epidemiology frequencies group identify individual infection level Infectious diseases Mathematics and computing Pandemics personal characteristic Population raise reducing Risk factors vaccination Vaccine Vaccines [DOI] 10.1038/s41598-021-04428-9 PMC 바로가기 [Article Type] Article
A Pre-Vaccination Baseline of SARS-CoV-2 Genetic Surveillance and Diversity in the United StatesSARS-COV-2 유전자 감시 및 미국의 다양성의 예방 접종 기준Article Published on 2022-01-072022-09-10 Journal: Viruses [Category] SARS, 변종, 치료기술, 치료제, [키워드] Administered Amino acid amino acid change amino acid changes Analysis conducted COVID-19 COVID-19 vaccine COVID-19 vaccines distributions Diversity expected frequencies Frequency Genetic genetic diversity geographical distributions immune pressure immunologically Infection linkage measure naïve Pathogens pre-vaccination remained RNA virus SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 in United States shifting Spread Support Surveillance the United State uniformity United States variants of concern Viral viral evolution virus spread VOCs widespread [DOI] 10.3390/v14010104 PMC 바로가기 [Article Type] Article
Association and predictive value of biomarkers with severe outcomes in hospitalized patients with SARS-CoV-2 infectionSARS-COV-2 감염이있는 입원 환자에서 심각한 결과를 가진 바이오 마커의 연관 및 예측 가치Multicenter Study Published on 2022-01-012022-08-31 Journal: Cytokine [Category] MERS, SARS, 바이오마커, [키워드] Admission Analysis analyzed association Biomarker Biomarkers Blood urea nitrogen Chi-square chi-square tests Coagulation COVID-19 Critical care Cytokines Cytokines and inflammatory mediators D-dimer disease severity Factor frequencies Frequency Growth factors hematological hospitalized patient hyper-inflammation ICU IL-6 IMV in-hospital mortality Inflammation Inflammatory Inflammatory marker inflammatory markers Inflammatory mediators intensive care Invasive mechanical ventilation Kidney function Mann-Whitney U Mechanical mechanical ventilation Mortality multivariable logistic regression Multivariable logistic regression analysis nitrogen outcome outcomes PaO Patient patients hospitalized Platelet Platelet count predict Predictive reduced respiratory Respiratory function risk Risk factors SARS-COV-2 infection suffered the disease urea Ventilation was performed with COVID-19 [DOI] 10.1016/j.cyto.2021.155755 PMC 바로가기 [Article Type] Multicenter Study
Cross-reactive and mono-reactive SARS-CoV-2 CD4+ T cells in prepandemic and COVID-19 convalescent individuals전염병 및 COVID-19 회복기 개인의 교차 반응성 및 단일 반응성 SARS-CoV-2 CD4+ T 세포Research Article Published on 2021-12-292022-09-10 Journal: PLoS Pathogens [Category] SARS, 치료기술, 치료법, [키워드] Activation allele Amino acid amino acid sequence Amino acid sequences Analysis assays Author CD4+ T cell class common cold common cold coronavirus common cold Coronaviruses common cold virus common cold viruses contributed convalescent convalescent individual convalescent individuals coronavirus COVID-19 cross-react cross-reactive cross-reactivity defined demonstrated Direct dominant epitope DPB1 elicit elicited Endemic epitope Epitopes Ex vivo frequencies Frequency functional HLA-DP HLA-DR identify immunodominant low frequency marker membrane MHC-II naïve individuals nucleocapsid Nucleocapsid proteins overlapping PBMC peptide peptides Potential prevalent Previous studies previous study proportion protective immunity Protein reactive reagent recognizing SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 epitope SARS-CoV-2 epitopes sequence identity shown spike staining stratified subjects suggested T cell T cell epitope T cell epitopes T cell response T cell responses T cells the Spike to define unlikely viruses was used were used world population [DOI] 10.1371/journal.ppat.1010203 PMC 바로가기 [Article Type] Research Article
Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational studyObservational Study Published on 2021-12-282022-10-04 Journal: Thoracic cancer [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, [키워드] acute respiratory syndrome adverse event age Analysis anticancer anticancer drug anticancer drugs BNT162b2 Chemotherapy comparable coronavirus COVID‐19 dose enrolled evaluated Fatality rate Fever frequencies healthy healthy individuals in healthy individuals increase in lung cancer lung cancer patient Male sex Messenger RNA mRNA mRNA vaccination mRNA vaccine multicenter multivariate analyses multivariate logistic regression participant Patient patients prevalent receive receiving Result RNA Safe SARS‐CoV‐2 SARS‐CoV‐2 severe cases the mean the patient Therapies therapy treated Treatment Trial tyrosine kinase inhibitors vaccination Vaccine vaccine injection were used [DOI] 10.1111/1759-7714.14281 PMC 바로가기 [Article Type] Observational Study
Agent-based simulations for protecting nursing homes with prevention and vaccination strategies예방 및 예방 접종 전략으로 요양원을 보호하기 위한 에이전트 기반 시뮬레이션Life Sciences–Mathematics interface Published on 2021-12-222022-09-10 Journal: Journal of the Royal Society Interface [Category] SARS, 변종, 진단, 치료기술, [키워드] absence agent agent-based simulations average calibrated condition COVID-19 pandemic develop effective Effectiveness Efficacy epidemiological frequencies high viral load identify index case infect Infection infection dynamics infections less long-term care facilities measure mitigation testing Non-pharmaceutical interventions nursing homes Older other person outbreak prevention strategies retention SARS-CoV-2 Sequencing Spread test result the residents threshold thresholds Transmission Vaccination strategy Vaccinations Vaccine vaccine efficacy variants of concern Viral Viral load virus genome virus genomes [DOI] 10.1098/rsif.2021.0608 PMC 바로가기 [Article Type] Life Sciences–Mathematics interface
Decline in Uptake of Childhood Vaccinations in a Tertiary Hospital in Northern Ghana during the COVID-19 PandemicResearch Article Published on 2021-12-142022-10-27 Journal: BioMed Research International [Category] COVID-19, [키워드] Analysis antenatal care approach BCG Child welfare childhood children clinic conducted COVID-19 COVID-19 infection COVID-19 pandemic curative curtail Decline defined Diseases Factor fear FIVE frequencies Healthcare provider immunization Measle Microsoft Excel MR1 negatively affected outbreak pandemic pandemic era percentages Perspective Quantitative reduction in Regular rubella Study design Tamale Teaching Tertiary the vaccine uptake vaccination Vaccine was done was used [DOI] 10.1155/2021/6995096 PMC 바로가기 [Article Type] Research Article