Factors associated with the intention of Syrian adult population to accept COVID19 vaccination: a cross-sectional studyResearch Published on 2021-07-042022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] age approach children conducted coronavirus COVID-19 COVID-19 vaccine COVID19 cross-sectional Demographic factors develop Efficacy Factor Gender global effort increasingly Intention knowledge male overcome pandemic participant Population positive predictor proportion questionnaire required Result severity Side effect smoking Syria the primary endpoint the vaccine vaccinated against COVID-19 vaccination Vaccine Vaccine hesitancy [DOI] 10.1186/s12889-021-11361-z PMC 바로가기 [Article Type] Research
Operation Warp Speed: implications for global vaccine securityOperation Warp Speed: 글로벌 백신 보안에 미치는 영향Review Published on 2021-07-012022-09-11 Journal: The Lancet. Global health [Category] 신약개발, 임상, [키워드] AstraZeneca clinical testing COVID-19 COVID-19 vaccines develop Efficacy effort Emergency use equity Expanded access funding global effort group Health implication Informed consent Interim analyses interim analysis Johnson & Johnson Johnson & Johnson Justice mechanism Microbiology Moderna nine Novavax operation Pfizer Phase 3 populations provided question Sinopharm Sinovac speed transition Vaccine [DOI] 10.1016/S2214-109X(21)00140-6 PMC 바로가기 [Article Type] Review
Inter-provincial disparity of COVID-19 transmission and control in NepalArticle Published on 2021-06-252022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] Analysis basic reproduction number caused Control COVID-19 case COVID-19 cases COVID-19 pandemic COVID-19 transmission disease effective Epidemic global effort growth identify India Infectious diseases linear Local Mathematics and computing mitigate Nepal outcome per day provide Reproduction number reproduction numbers resulting significantly Spread the disease the epidemic the median Transmission unique Variation [DOI] 10.1038/s41598-021-92253-5 PMC 바로가기 [Article Type] Article
Unravelling the Role of Socioeconomic Forces in the Early Stage of COVID-19 Pandemic: A Global AnalysisCase Report Published on 2021-06-112022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] addition Analysis assumption Clinical features Consequences Contagion contagions COVID-19 COVID-19 pandemic death rate dimension dissemination driven by early stage empirical finding epidemiological force global effort Health Health policy health system healthcare healthcare service Hospitalization implication indicators mechanisms Pandemics resource Result Risk factors role severity significantly Stage supported Transmission virus [DOI] 10.3390/ijerph18126340 PMC 바로가기 [Article Type] Case Report
Ayurveda botanicals in COVID-19 management: An in silico multi-target approachCovid-19 관리의 Ayurveda 식물 : In In Silico Multi-Target 접근Research Article Published on 2021-06-112022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료제, [키워드] adjuvant Administered Antiviral antiviral activity approach Asparagus Ayurveda caused contagious contagious disease coronavirus coronavirus disease COVID-19 disease docking drug therapy Effects evaluate experimental validation global effort global efforts global pandemic immune pathway immune pathways immunomodulators immunomodulatory in silico in-silico India Interaction life cycle management mass spectrometry modulate network pharmacology predict predicted Predictive protective role Protein racemosus Rasayana RNA RNA dependent RNA polymerase RNA polymerase SARS-CoV-2 SARS-CoV2 specific treatment Spike protein target targets termination the disease the Spike therapeutic therapy UHPLC Vaccine Viral viral life cycle virus was performed [DOI] 10.1371/journal.pone.0248479 PMC 바로가기 [Article Type] Research Article
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivativesArticle Published on 2021-05-242022-10-04 Journal: Nature Communications [Category] SARS, 치료제, [키워드] Analysis antiviral activity binding mode catalytic dyad Critical crystal structures crystallographic structure cysteine demonstrated derivative derivatives develop Drug discovery and development Ebselen enzyme examined global effort hydrolysis infected cell inhibit inhibition investigated M pro mechanism pandemic protease reactivity SARS-CoV-2 SARS-CoV-2 main protease the SARS-CoV-2 therapeutic these compound triggered viral replication viruses X-ray crystallography zoonotic [DOI] 10.1038/s41467-021-23313-7 PMC 바로가기 [Article Type] Article
Identification of a novel inhibitor of SARS-CoV-2 3CL-PRO through virtual screening and molecular dynamics simulationComputational Biology Published on 2021-04-132022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 3CL-Pro adopted analyzed antiviral drug approach AutoDock binding caused chemotypes Compound compounds computation conformational coronavirus coronavirus diseases COVID-19 COVID-19 pandemic crystal structures crystallographic structure demonstrated develop deviation Diversity docking drug candidate effective FDA-approved drug fluctuation Frame global effort globe Gromacs High-resolution identification in silico indicated inhibitor insight interval library Ligand ligands main protease molecular docking Molecular dynamics simulation molecular target MPro oral bioavailability other molecules over parameters performed pharmacokinetic Physicochemical properties predicted profiles protease protein-ligand protein-ligand interaction protein-ligand interactions Result RMSD RMSF Safe SARS-CoV-2 selected small molecule target protein the SARS-CoV-2 the SARS-CoV-2 virus Toxicity trajectory treat Vina viral disease Virtual screening while X-ray crystallographic structure [DOI] 10.7717/peerj.11261 PMC 바로가기 [Article Type] Computational Biology
Application of Artificial Intelligence in COVID-19 Pandemic: Bibliometric AnalysisArticle Published on 2021-04-092022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] Academy Analysis application article articles artificial artificial intelligence authors bibliometric analysis China Chinese co-occurrence network conducted coronavirus country COVID-19 domain English language Fractal global effort Health healthcare India information intelligence Internet journal Leiden machine learning peer-reviewed PLOS Practitioner R package Research researchers Science solution systematic literature search technology university USA Web of Science were used Wuhan [DOI] 10.3390/healthcare9040441 PMC 바로가기 [Article Type] Article
COVID-19 research priorities for non-pharmaceutical public health and social measuresShort Paper Published on 2021-04-052022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome approach behavioural conducted Contact tracing Control coronavirus COVID-19 COVID-19 epidemic COVID-19 research effective element Epidemic Europe European global effort help measure Measures mental health physical distancing prevention public health Research Surveillance Transmission [DOI] 10.1017/S0950268821000716 PMC 바로가기 [Article Type] Short Paper
The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression on the Incidence and Severity of COVID-19 InfectionReview Published on 2021-03-222022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] ACE2 ACE2 expression angiotensin-converting enzyme 2 Anti-viral Community comorbid condition coronavirus COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 pathogenesis Evidence explain functional global effort group groups highlight Hypothesis Impact incidence Infection Interaction International Mortality novel coronavirus disease pandemic potential therapeutic target Prevalence preventive measure public health raised SARS-CoV-2 severity of COVID-19 Support therapeutic Variation viral spike protein [DOI] 10.3390/pathogens10030379 PMC 바로가기 [Article Type] Review