Glutamine
[대역어] 글루타민
[용어속성] Compound
[용어속성] Compound
Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
GLS2의 인간 유전적 변이는 복잡한 황색 포도구균 균혈증의 발병과 관련이 있습니다
Research Article
[키워드] activate
age
allele
Analysis
association
Bacteremia
Bacteria
Bacterial
Blood cells
bloodstream
Bonferroni correction
candidate gene
capture
cause
causes
Cell
coding variant
complex
Complication
Control
correlated
CRISPR
CRISPR-Cas9
cumulative
cumulative effect
death
eight
ENCODE
evaluated
examined
exhibited
Exome
expression
expression level
Factor
Frequency
gene-based analysis
gene-expression
Genetic
genetic factors
genetic risk factor
Genetic variant
genetic variants
Genetic variation
Genome
GLS2
Glutamine
growth
healthy controls
Hospitalization
Host
Human
Human genome
immune response
individual
Infection
infections
Interaction
key factor
leukocyte
leukocyte activation
Logistic regression analysis
Macrophage
macrophage cells
metabolism
Microarray
missense variant
nitric oxide
plasma concentration
Protein
regulate
Regulatory
Replication
risk
S . aureus
sequence
Sequencing
Sex
significantly
significantly lower
Staphylococcus aureus
susceptible
the strongest
These cells
Transcription
variant
variants
Variation
variations
WES
White blood cell
White blood cells
wild-type cells
[DOI] 10.1371/journal.pgen.1007667 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1007667 PMC 바로가기 [Article Type] Research Article
Sequence features governing aggregation or degradation of prion-like proteins
프리온 유사 단백질의 응집 또는 분해를 제어하는 서열 특징
Research Article
[키워드] aggregate
aggregates
aggregation
aliphatic
Alzheimer’s disease
Amino acid
amino acid sequence
amino acids
Amyotrophic lateral sclerosis
aromatic residue
aromatic residues
asparagine
cellular
classical
clearance
complex interplay
control systems
correlated
Degradation
Diseases
domain
domains
dose-dependent
elicited
enhanced
eukaryotic
evade
Factor
Factors
feature
Features
Frequency
Genetic
genetic screen
Glutamine
glycine
highlight
hnRNPA1
human protein
human proteins
increase in
intrinsic
Lateral Sclerosis
lead
neurodegenerative disorder
neurodegenerative disorders
occur
Prevent
promote
promoted
Protein
protein quality control
Proteins
Quality control
recognize
recognizing
residue
second
sequence
stimulate
subset
suppressed
to define
variety
while
yeast
[DOI] 10.1371/journal.pgen.1007517 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1007517 PMC 바로가기 [Article Type] Research Article
Heterologous Aggregates Promote De Novo Prion Appearance via More than One Mechanism
이종 골재는 하나 이상의 메커니즘을 통해 De Novo Prion 모양을 촉진합니다.
Research Article
[키워드] absence
aggregate
aggregates
aggregation
appear
appearance
asparagine
Cell
cells
cellular
chaperone
characteristic
Colocalization
conformational
cytoplasm
de novo
detect
disease
domains
eukaryotic
form
Glutamine
Heterologous
Interaction
lack
mechanisms
molecular
MOST
neurodegenerative
no interaction
open
overexpressed
overexpression
pathway
periphery
phenotypic
phenotypic traits
physical
Polymer
prevalent
prion
promote
Protein
Proteins
PSI
required
seed
stimulated
the cell
traits
vacuole
variant
while
yeast
[DOI] 10.1371/journal.pgen.1004814 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1004814 PMC 바로가기 [Article Type] Research Article
The SARS Coronavirus 3a protein binds calcium in its cytoplasmic domain
Article
[키워드] aligned
amino acid residue
amino acids
Analysis
bind
binding
calcium
cause
conformational change
Cyto3a protein
cytoplasmic
domain
E. coli
ENCODE
enzyme
expressed
form
Genome
Glutamine
His-tagged
Hypothesis
in viral
in vitro
in vivo
involved
ion channel
Leptospira
Open reading frame
ORF, open reading frame
Pathogenesis
Plasmodium falciparum
positive
predicted
Protein
Protein conformation
purified
respiratory
RNA virus
SARS-CoV
SARS-CoV, severe acute respiratory syndrome coronavirus
sequence similarity
staining
Support
virus
[DOI] 10.1016/j.virusres.2014.08.001 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.virusres.2014.08.001 PMC 바로가기 [Article Type] Article
Revealing natural antisense transcripts from Plasmodium vivax isolates: evidence of genome regulation in complicated malaria
article
[키워드] 1,3 BPG
1,3-biphosphoglycerate
2-Oxaloglutarate
2-phophoglycerate
2OG
2PG
3-phosphoglycerate
3PG
6-phophogluconate
6-phosphoglucono-δ-lactone, 6PGNT, 6-phophogluconate
6PGNL
6PGNT
AC-COA
acetyl-CoA
ACON-C
ASP
aspartate
cis-aconitate
CIT
citrate
Complicated malaria
deoxyribose-1-phosphate
deoxyribose-5-phosphate
deoxyribose-phosphate aldolase
DHAP
dihydroxy-acetone-phosphate
DR1P
DR5P
E4P
erythrose-4-phosphate
F-6-P
F6P
FBP
fructose 1,6-bis phosphate
fructose 1,6-bisphosphate aldolase
fructose-6-phosphate
FUM
fumarate
G-6-P
G3P
Gap
GDP-4-oxo-6-deoxy-mannose
GDP-FUC
GDP-Fucose
GDP-L-fucose synthetase
GDP-MAN
GDP-Mannose
GDP-ODM
GLC
GLCN6P
GLCNAC1P
GLCNAC6P
Gln
GLU
glucosamine-6-phosphate
glucosamine-fructose-6-phosphate aminotransferase
Glucose
Glucose-6-phosphate
Glutamate
Glutamine
GLYC
GLYC3P
glyceraldehyde 3-phosphate
glyceraldehyde-3-phophate
glycerol
glycerol-3-phosphate
ICT
Isocitrate
lac
Lactate
MAL
malate
Man
MAN1P
MAN6P
mannose
mannose-1-phosphate
mannose-6-phosphate
N-acetyl-glucosamime-6-phosphate
N-acetyl-glucosamine-1-phosphate
Natural antisense transcripts
OXA
Oxaloacetate
PEP
phosphoenolpyruvate
phosphoglycerate kinase
Plasmodium vivax
PVX_001945
PVX_080515
PVX_091100
PVX_094915
PVX_099535
PVX_111455
PVX_118255
PVX_118495
PYR
pyruvate
R5P
ribose 5-phosphate epimerase
ribose-5-phosphate
ribulose-5-phosphate
Ru5P
S7P
sedoheptulose-7-phosphate, F6P, fructose-6-phosphate
Strand specific microarray
SUC
SUC-COA
succinate
succinyl-COA
succinyl-CoA synthetase alpha subunit
triosephosphate isomerase
UDP-GLCNAC
UDP-N-acetyl-glucosamine. Gene coding for protein:PVX_114315, hexokinase, putative
Uncomplicated malaria
X5P
xylulose-5-phosphate, G3P, glyceraldehyde-3-phophate
[Article Type] article
[Article Type] article
Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans
Caenorhabditis elegans의 소포 수송에 의한 세포 간 프리온 도메인의 확산
Research Article
[키워드] aggregate
aggregation
ALS
amyloid
Amyotrophic lateral sclerosis
animal model
appearance
asparagine
Author
autonomous
autophagy
Caenorhabditis
Caenorhabditis elegan
Caenorhabditis elegans
Cell
cellular
cellular pathway
conformation
culture cell
cytosolic
Degradation
developmental delay
different
disease
Diseases
domain
elegan
embryonic
Encephalopathy
Epigenetic
Evidence
exhibit
expressed
expressing
expression
form
Glutamine
hallmark
hallmarks
include
infect
infectious
Lateral Sclerosis
lobar
lysosomal
lysosomal vesicle
mechanism
misfolded protein
misfolded proteins
mitochondrial
multicellular
multicellular organism
N-terminus
naive cells
neurodegenerative
neurodegenerative disorders
NM
organism
Parkinson's Disease
pathology
pathway
prion
Propagation
Protein
Proteins
real time
recent
Spread
spreading
thought
tissue
tissue culture
tissues
Toxicity
trait
transgenic mice
transmissible spongiform encephalopathies
Transmission
Transport
underlie
Vesicle
vesicular
widespread
yeast
[DOI] 10.1371/journal.pgen.1003351 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1003351 PMC 바로가기 [Article Type] Research Article
A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington’s Disease
게놈 규모의 RNA-간섭 스크린은 헌팅턴병의 병리학적 특징으로 RRAS 신호를 식별합니다
Research Article
[키워드] Activation
addition
Amino acid
amino-terminus
Analysis
Author
cascade
caused
Cell
cellular
cellular processe
cellular processes
component
disease
disorder
Drosophila
dysfunction
effective
ENCODE
enzyme
excitotoxicity
farnesyltransferase
FNTA
found
functional
Glutamate
Glutamine
huntingtin
Huntington's disease
identify
implicated
in addition to
increase in
inhibitor
Interaction
Intervention
involved
Localization
loss-of-function
mammalian
mechanism
mechanisms
mitochondrial
mitochondrial dysfunction
motor dysfunction
mouse model
mutant
Mutation
observé
occur
pathogenic
pathway
Pathways
pharmacological
PIN1
PLK1
Protein
proteolysis
RAF1
reduce
reduced
reducing
repeated
RNA interference
RRAS
Screen
Signaling
signaling pathway
small molecule
solubility
suppress
suppressed
suppressor
Therapeutic benefit
These data
Toxicity
was performed
[DOI] 10.1371/journal.pgen.1003042 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1003042 PMC 바로가기 [Article Type] Research Article
The SARS Coronavirus S Glycoprotein Receptor Binding Domain: Fine Mapping and Functional Characterization
Research
[키워드] ACE2
Alanine
amino acid residue
appear
binding
binding energy
Cell
characterization
characterized
cloned
contribute
decrease
determined
eight
expressed
expression
functional
Glutamine
glycoprotein
glycosylation
glycosylation site
identify
immune responses
include
indicate
initiated
kDa
lack
Li
mapping
mechanism
molecular weight
Mutagenesis
mutated
Mutation
not affect
R426
RBD
receptor
receptor ACE2
reduced
required
residue
residues
S RBD
SARS Coronavirus
significantly
Simultaneous
submitted
suggested
the RBD
the receptor-binding domain
These data
[DOI] 10.1186/1743-422X-2-73 PMC 바로가기 [Article Type] Research
[DOI] 10.1186/1743-422X-2-73 PMC 바로가기 [Article Type] Research