Role of Nutraceuticals in COVID-19 Mediated Liver DysfunctionCOVID-19 매개 간 기능 장애에서 기능 식품의 역할Review Published on 2020-12-132022-09-10 Journal: Molecules [Category] MERS, SARS, 치료제, [키워드] ACE2 an area Antiviral antiviral therapy benefit co-morbidities co-morbidity coronavirus COVID-19 epidemiological studies Health health benefits hepatic dysfunctions hepatoprotective agents hepatotoxicity immunomodulatory increased risk information Injury juncture liver dysfunction management Mediated mitigate morbidities nutraceutical nutraceuticals Pandemics planet provide reported Research role SARS-CoV-2 Spread therapy virus with COVID-19 [DOI] 10.3390/molecules25245905 PMC 바로가기 [Article Type] Review
Hepatic Disorders With the Use of Remdesivir for Coronavirus 2019코로나바이러스 2019에 렘데시비르를 사용한 간 장애Multicenter Study Published on 2020-11-012022-09-11 Journal: Clinical gastroenterology and hepatology : the off [Category] Coronavirus, SARS, 비임상, [키워드] Adverse drug reaction adverse event adverse events Aminotransferase antiviral activity available data Bilirubin breath broad spectrum Cell culture cell cultures clinical development clinical trials Cohort studies cohort study compassionate-use coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients disorder double-blind drug drug reaction Drug-induced liver injury elevated EMA European Medicines Agency FDA food healthy volunteer healthy volunteers hepatic hepatic enzyme hepatic enzymes hepatotoxicity hospital human coronavirus increase Infection Intravenous remdesivir investigator investigators Liver injury mouse model Mouse models nucleotide Patient patients hospitalized patients with COVID-19 Placebo placebo recipient placebo recipients placebo-controlled clinical trial proportion raised Randomized recipient Remdesivir reported respiratory safety profile Severe acute respiratory syndrome Severe Acute Respiratory Syndrome-associated Coronavirus 2 severe coronavirus disease severe COVID-19 treated Treatment [DOI] 10.1016/j.cgh.2020.07.050 PMC 바로가기 [Article Type] Multicenter Study
Decreased serum albumin level indicates poor prognosis of COVID-19 patients: hepatic injury analysis from 2,623 hospitalized cases혈청 알부민 수치 감소는 COVID-19 환자의 나쁜 예후를 나타냅니다: 2,623명의 입원 사례에서 간 손상 분석Article Published on 2020-11-012022-09-11 Journal: Science China. Life sciences [Category] SARS, 유전자 메커니즘, [키워드] activated Admission adult COVID-19 patient albumin Analysis aPTT cause caused Chinese cholesterol clinical Clinical outcome clinically Coagulopathy Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Critical Critically ill Critically ill patient critically ill patients cytokine Cytokine storm Cytokines death death group Decreased diagnosed disease-associated elevated enrolled Exacerbation global pandemic groups guideline HDL HDL-C hepatic injury hepatic injury. hepatotoxicity high-density High-density lipoproteins hospital Hospitalization Hospitalized Hypoalbuminemia hypoproteinemia indicate Inflammatory cytokine Inflammatory cytokines inflammatory factors Inflammatory response Inflammatory responses interquartile range investigated IQR LDL LDL-C leads lipoprotein liver dysfunction low-density Low-density lipoprotein low-density lipoproteins median age occurred on admission partial thromboplastin time Patient poor prognosis progression reflected Retrospective study serum serum albumin significantly lower survivor the disease the patient three groups THROMBOPLASTIN Tongji Hospital were measured Wuhan, China [DOI] 10.1007/s11427-020-1733-4 PMC 바로가기 [Article Type] Article
Nilotinib-Induced Immune-Mediated Liver Injury: Corticosteroid as a Possible Therapeutic OptionArticle Published on 2020-07-102023-08-30 Journal: Frontiers in Oncology [Category] E형 간염, [키워드] chronic myeloid leukemia Corticosteroid Drug induced liver injury hepatotoxicity Nilotinib [DOI] 10.3389/fonc.2020.01160 PMC 바로가기
Effects of antifungal stewardship using therapeutic drug monitoring in voriconazole therapy on the prevention and control of hepatotoxicity and visual symptoms: A multicentre study conducted in JapanOriginal Article Published on 2020-06-252024-09-02 Journal: Mycoses [Category] 대상포진, [키워드] antifungal stewardship hepatotoxicity Therapeutic Drug Monitoring visual symptoms voriconazole [DOI] 10.1111/myc.13129 PMC 바로가기 [Article Type] Original Article
Liver safety assessment in clinical trials of new agents for chronic hepatitis BReview Published on 2020-02-012023-06-13 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] antivirals causality assessment Drug development HBV hepatotoxicity [DOI] 10.1111/jvh.13223 [Article Type] Review
Epigallocatechin-3-Gallate Toxicity in Children: A Potential and Current Toxicological Event in the Differential Diagnosis With Virus-Triggered Fulminant Hepatic FailureReview Published on 2020-01-292023-08-30 Journal: Frontiers in Pharmacology [Category] E형 간염, [키워드] acute liver failure green tea hepatotoxicity metabolism pediatrics Pharmacology subcellular environment Toxicity [DOI] 10.3389/fphar.2019.01563 PMC 바로가기 [Article Type] Review
Exogenous Ghrelin Could Not Ameliorate 3,4-methylenedioxymethamphetamine-induced Acute Liver Injury in The Rat: Involved MechanismsOriginal Article Published on 2020-01-012024-09-02 Journal: Iranian Journal of Pharmaceutical Research : IJPR [Category] 대상포진, [키워드] 4-methylenedioxymethamphetamine Apoptosis ghrelin hepatotoxicity Necrosis TNF-α [DOI] 10.22037/ijpr.2020.1100940 PMC 바로가기 [Article Type] Original Article
Risk Factors for Alanine Aminotransferase Elevations in a Prospective Cohort of HIV-Infected Tanzanian Adults Initiating Antiretroviral TherapyArticle Published on 2019-10-312023-06-03 Journal: Journal of the International Association of Provid [Category] B형 간염, [키워드] ALT antiretroviral Hepatitis hepatotoxicity HIV liver [DOI] 10.1177/2325958219884939 PMC 바로가기
Strategies for Early Prediction and Timely Recognition of Drug-Induced Liver Injury: The Case of Cyclin-Dependent Kinase 4/6 InhibitorsReview Published on 2019-10-242023-08-30 Journal: Frontiers in Pharmacology [Category] E형 간염, [키워드] Drug-induced liver injury hepatotoxicity predictivity risk ranking signal detection [DOI] 10.3389/fphar.2019.01235 PMC 바로가기 [Article Type] Review