Whole-genome analysis of SARS-CoV-2 in a 2020 infection cluster in a nursing home of Southern Italy남부 이탈리아 요양원의 2020년 감염 클러스터에서 SARS-CoV-2의 전체 게놈 분석Article Published on 2022-04-012022-09-12 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Analysis analyzed association B.1 lineage Calabria carried clade clinical parameter Cluster COVID-19 D614G Evolution Frequency Genome Haplotype haplotypes help hotspot indicated Infection initial investigated IQ-TREE Italy NC_045512.2 next generation sequencing NGS nursing home outbreak Pandemics Patient patients predominant responsible SARS-CoV-2 SARS-CoV-2 viral sequence single nucleotide variation SNV SNVs South Spread Swab UTR viral genome viral spread viral strain Viral transmission [DOI] 10.1016/j.meegid.2022.105253 PMC 바로가기 [Article Type] Article
Global analysis of the COVID-19 research landscape and scientific impactResearch article Published on 2022-04-012022-10-05 Journal: American journal of infection control [Category] 신약개발, [키워드] Analysis analyzed Bibliometric confirmed case coronavirus disease Correlation analysis correlations country COVID-19 COVID-19 research database death deaths determine driving epidemiological GraphPad Prism hotspot IBM in-depth analysis indicated information Keyword co-occurrence limitation Microsoft Excel objective pandemic positive correlation provided public health emergency Publication trend Quantitative data Research Result SPSS Web of Science were used [DOI] 10.1016/j.ajic.2021.12.025 [Article Type] Research article
The mutational dynamics of the SARS-CoV-2 virus in serial passages in vitro시험관 내 연속 계대에서 SARS-CoV-2 바이러스의 돌연변이 역학Article Published on 2022-04-012022-09-11 Journal: Virologica Sinica [Category] COVID19(2023년), SARS, 변종, [키워드] accumulating acute respiratory syndrome coronavirus adaptation adaptive analysed boost Cell culture cell line change coding Combination Community competition coronavirus 2 directional effective Evolution explained Frequency Gene pool genetic change Genetic changes hotspot immune escape mutation in vitro insertions Mutation Mutational dynamics Neutral outbreak passage path performed potency Replication respiratory RT-qPCR SARS-CoV-2 SARS-CoV-2 strains Sequencing Serial passage in vitro severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 species speed strain Substitution the SARS-CoV-2 the SARS-CoV-2 virus unique variants WGS whole genome Whole genome sequencing Whole genome sequencing (WGS) [DOI] 10.1016/j.virs.2022.01.029 PMC 바로가기 [Article Type] Article
Comparative Analysis of SARS-CoV-2 Variants of Concern, Including Omicron, Highlights Their Common and Distinctive Amino Acid Substitution Patterns, Especially at the Spike ORF오미크론을 포함한 우려되는 SARS-CoV-2 변이체의 비교 분석은 특히 스파이크 ORF에서 공통적이고 독특한 아미노산 치환 패턴을 강조합니다Comparative Study Published on 2022-03-292022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] acid Alpha Amino acid amino acid substitution amino acid substitutions Analysis Beta common Comparative concern COVID-19 Delta dN/dS Evolution Gamma highest homologous hotspot human host Hypothesis Including introduced investigated Lambda Lineage lineages mutated mutations omicron ORF phylogenetic distribution Point mutation Positive selection RBD Receptor binding domain Recombination recurrent mutations residue Sarbecoviruses SARS-CoV-2 significantly higher spike Substitution the Spike vaccination variant variants variants of concern was performed [DOI] 10.3390/v14040707 PMC 바로가기 [Article Type] Comparative Study
Tackling the emerging threat of antifungal resistance to human health Reviews Published on 2022-03-292022-10-05 Journal: Nature reviews. Microbiology [Category] 진단, [키워드] Bacterial diagnostics drugs fungal Fungal infection fungi global effort Health highlight hotspot include main mechanism mitigate one health pathogenic populations public health required Research review risk reduction similarity Surveillance therapy Transmission [DOI] 10.1038/s41579-022-00720-1 [Article Type] Reviews
Phylogenetic analysis of 17271 Indian SARS-CoV-2 genomes to identify temporal and spatial hotspot mutations17271 인도 SARS-CoV-2 게놈의 계통 발생 분석을 통해 시간 및 공간 핫스팟 돌연변이 식별Article Published on 2022-03-282022-09-11 Journal: PLoS ONE [Category] SARS, 변종, [키워드] affected aligned Analysis biological function Biological functions carried changes in Characteristics coding region coding regions country COVID Entropy evaluate evaluated followed by functional hotspot identify India MAFFT moderate Multiple sequence alignment Mutation mutations Nextstrain Non-synonymous Patient performed Phylogenetic analysis PolyPhen-2 Protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 sequence second wave sequence Sequence alignment sequences SNP SNPs stability vaccination virus strains [DOI] 10.1371/journal.pone.0265579 PMC 바로가기 [Article Type] Article
Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution바이러스 특정 편집 식별 접근 방식은 A-to-I 편집 환경과 SARS-CoV-2 특성 및 진화에 미치는 영향을 보여줍니다.Article Published on 2022-03-212022-09-11 Journal: Nucleic Acids Research [Category] SARS, 변종, 유전자 메커니즘, 치료법, [키워드] accelerated activate Affect antigenicity Antiviral approach atlas average cell types Characteristics component components correlated dsRNA event Evidence Evolution expression framework Genome highlight Host hotspot Human IFN response Impact induce infected with SARS-CoV-2 innate immune response intensity MDA5 provide provided regulated resource reveal RNA RNA virus RNA-seq data SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection spike gene the epidemic tissue viral dsRNA viral infectivity Viral RNA [DOI] 10.1093/nar/gkac120 PMC 바로가기 [Article Type] Article
Tourists perceptions of Caribbean islands facing environmental threats before the COVID-19 health crisis: Holbox Island and Archipelago of Bocas del ToroResearch Article Published on 2022-03-092022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] archipelago build conscious COVID-19 demonstrated driven by Effect environmental threat finding Health help hotspot Impact island knowledge lack Latin America Local overcome Population Prevent promote regions Resilience Result similarity Support survey understanding [DOI] 10.1371/journal.pone.0262014 PMC 바로가기 [Article Type] Research Article
Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany독일 뮌헨 대학교 병원 직원 4,554명 중 SARS-CoV-2 IgG의 감염 관리 측정 및 유병률Research Published on 2022-03-012022-09-12 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome antibodies Contact Control coronavirus coronavirus disease Coronaviruses COVID-19 COVID-19 patient cross-sectional determine Factors Germany healthcare facility Healthcare workers high risk hospital Hospital staff hotspot identify IgG Increased Infection Infection Control measures Infection prevention Interaction Isar measure modulating Munich overlap pandemic participant Patient Patient care Personal protective equipment Prevalence Probability respiratory infections Safe SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection seropositive Seroprevalence severe acute respiratory syndrome coronavirus 2 spatiotemporal staff Strategies the SARS-CoV-2 trajectory university university hospital employees viruses zoonoses [DOI] 10.3201/eid2803.204436 PMC 바로가기 [Article Type] Research
Deep recurrent reinforced learning model to compare the efficacy of targeted local versus national measures on the spread of COVID-19 in the UK영국에서 Covid-19의 확산에 대한 표적화 된 지역과 국가적 조치의 효능을 비교하기위한 깊은 재발 강화 학습 모델Epidemiology Published on 2022-02-212022-09-10 Journal: BMJ Open [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] addition applied Combination correlation coefficient COVID-19 COVID-19 case COVID-19 cases curated deep effective Effectiveness Efficacy England Epidemiology evaluate health informatics high risk highlight hotspot imperative infection control International Local lockdown MAE magnitude mean absolute error measure Measures Model mortalities Mortality National objective outbreak pandemic predict Prevent public health quarantine ranking Region regions required Result root secure social distancing Space spatiotemporal spread of COVID-19 strain Travel vaccination variant Virology [DOI] 10.1136/bmjopen-2020-048279 PMC 바로가기 [Article Type] Epidemiology