Hyperinflammatory syndrome – Page 4 – Communicable Diseases Research

Sonographic findings in coronavirus disease-19 associated liver damage

Clinical Trial

Published on 2021-02-192022-10-04
Journal: PLoS ONE [Category] MERS, 임상,

Pragmatic, open-label, single-center, randomized, phase II clinical trial to evaluate the efficacy and safety of methylprednisolone pulses and tacrolimus in patients with severe pneumonia secondary to COVID-19: The TACROVID trial protocol

Article

Published on 2021-01-192022-10-04
Journal: Contemporary Clinical Trials Communications [Category] 임상,

[키워드] 1:1 Arm assigned body temperature clinical clinical trial Coronavirus infection COVID-19 COVID-19 disease COVID-19 patient Cytokine storm defined drug drug combination effective Efficacy and safety evaluate Hyperinflammatory Hyperinflammatory syndrome Immunomodulatory agent Inflammation inhibit Lung injury Methylprednisolone Open-label paO2/fiO2 Patient pulmonary failure pulse randomization Randomized Randomly Replication respiratory rate Safe SARS-CoV-2 severe COVID-19 patients severe lung injury severe pneumonia single-center SOC stability Standard of care subsequent suggested tacrolimus treat treated Trial trial protocol triggered working hypothesis
[DOI] 10.1016/j.conctc.2021.100716 PMC 바로가기 [Article Type] Article

Successful treatment of severe COVID-19 pneumonia and hyperinflammatory syndrome with tocilizumab

토실리주맙으로 중증 COVID-19 폐렴 및 과염증 증후군의 성공적인 치료

Case Reports

Published on 2021-01-082022-09-12
Journal: BMJ case reports [Category] 진단,

Haemophagocytic syndrome and COVID-19

Review Article

Published on 2021-01-032023-06-16
Journal: Clinical Rheumatology [Category] MERS, SARS,

[키워드] COVID-19 Cytokine storm syndrome Haemophagocytic syndrome Hyperinflammatory syndrome macrophage activation syndrome Multisystem inflammatory syndrome
[DOI] 10.1007/s10067-020-05569-4 PMC 바로가기 [Article Type] Review Article

High Induction of IL-6 Secretion From hUCMSCs Optimize the Potential of hUCMSCs and TCZ as Therapy for COVID-19-Related ARDS

hUCMSC에서 IL-6 분비의 높은 유도는 COVID-19 관련 ARDS에 대한 치료법으로서 hUCMSC 및 TCZ의 잠재력을 최적화합니다

Article

Published on 2021-01-012022-09-12
Journal: Cell transplantation [Category] 진단,

[키워드] acute respiratory distress analyzed anti-inflammatory effect ARDS Biological Blood Cell cellular Concentration correlation COVID-19 cytokine secretion ELISA evaluated Exogenous expression functional hUCMSC Hyperinflammatory syndrome IL-6 IL-6 level IL-6 levels IL-6 neutralizing antibody IL-6 receptor IL-6R induction Inflammation inhibited inhibitory effect interleukin-6 less Microarray mononuclear cell mRNA expression MTT Neutralizing neutralizing antibody PBMC PBMCs peripheral Potential proliferation reached reported Respiratory failure Responder Severe COVID-19 pneumonia supernatant syndrome TCZ therapeutic potential therapy Tocilizumab treat umbilical was measured was used
[DOI] 10.1177/09636897211054481 PMC 바로가기 [Article Type] Article

Tocilizumab for the Treatment of COVID-19-Induced Cytokine Storm and Acute Respiratory Distress Syndrome: A Case Series From a Rural Level 1 Trauma Center in Western Pennsylvania

COVID-19 유발 사이토카인 폭풍 및 급성 호흡곤란 증후군 치료를 위한 토실리주맙: 서부 펜실베니아의 농촌 1급 외상 센터의 사례 시리즈

Case Reports

Published on 2021-01-012022-09-12
Journal: Journal of investigative medicine high impact case [Category] Coronavirus, 진단,

[키워드] acute respiratory distress acute respiratory syndrome antibody ARDS case sery caused center Clinical improvement coronavirus coronavirus disease Coronavirus-2 cough COVID-19 COVID-19 patient cytokine Cytokine storm dose female Fever hospital Hospitalized Hyperinflammatory syndrome hypoxia ICU ICU admission intensive care interleukin-6 interleukin-6 receptor intravenous Intubated intubation level 1 life-threatening nasal nausea outbreak Oxygen requirement patients treated patients with COVID-19 Pneumonia respiratory Sery Shortness of breath Spread storm supplemental oxygen syndrome therapeutic Tocilizumab transferred transitioned treated worsening Wuhan, China
[DOI] 10.1177/23247096211019557 PMC 바로가기 [Article Type] Case Reports

Multisystem inflammatory syndrome in children related to COVID-19: A New York City experience

COVID-19와 관련된 어린이의 다기관 염증 증후군: 뉴욕시 경험

Article

Published on 2021-01-012022-09-12
Journal: Journal of medical virology [Category] Fulltext, MERS, 진단,

COVID-19: IgG seroconversion under intensive glucocorticoid treatment in a high-risk patient with minimal change disease

COVID-19: 최소 변화 질환이 있는 고위험 환자에서 집중 글루코코르티코이드 치료 시 IgG 혈청 전환

Case Reports

Published on 2020-12-082022-09-12
Journal: Wiener Klinische Wochenschrift [Category] Coronavirus, MERS, SARS, 진단,

Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab

토실리주맙으로 치료받은 중증 코로나19 환자의 폐혈관 개선

Observational Study

Published on 2020-12-012022-09-11
Journal: Immunology letters [Category] MERS, SARS, 바이오마커, 임상, 진단,

[키워드] addition alveolar Alveolar-arterial oxygen gradient anti-IL-6 receptor CAR-T CAR-T cell therapy Cell therapy Chest-X ray clinical compassionate-use therapies contrary controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine release syndrome develop explain Hyperinflammatory syndrome IL-6 immunomodulatory Inflammatory marker inflammatory markers intensive care limitations management monoclonal antibody observational study occur off-label oxygen parameter Patient pulmonary radiologic receiving respiratory status retrospective severe COVID-19 severe COVID-19 patient Standard-of-care suggested supportive care therapy Tocilizumab tocilizumab - tocilizumab administration treated Treatment Vascular Vascular score. worsened
[DOI] 10.1016/j.imlet.2020.10.009 PMC 바로가기 [Article Type] Observational Study

Distinguishing between typical Kawasaki disease and multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2

SARS-CoV-2와 관련된 소아의 다기관 염증 증후군(MIS-C)과 전형적인 가와사키병의 구별

Article

Published on 2020-11-012022-09-12
Journal: Medical Hypotheses [Category] 진단,

[키워드] activate Activation acute respiratory syndrome Bone marrow CD8+ cell children classical Cohort coronavirus COVID-19 debate distinguishing Fc receptor FcR help Hyperinflammatory syndrome immune immune complex Immunoglobulin Immunopathogenesis Inflammatory inflammatory cell inflammatory cells Inflammatory response Intravenous immunoglobulin IVIG Kawasaki disease kill membranes MIS-C monocyte Neutrophils paediatrics Pathogenesis Patient PIMS-TS Platelet Platelets pro-inflammatory recruitment resulting SARS-CoV-2 secreted significantly lower stimulate suppress syndrome these cell thought viral infected cells virus
[DOI] 10.1016/j.mehy.2020.110263 PMC 바로가기 [Article Type] Article