ICU Patients – Page 4 – Communicable Diseases Research

Serum calprotectin as a novel biomarker for severity of COVID-19 disease

COVID-19 질병의 중증도에 대한 새로운 바이오마커로서의 혈청 칼프로텍틴

Article

Published on 2022-02-012022-09-11
Journal: Irish Journal of Medical Science [Category] MERS, 바이오마커,

Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients

COVID-19 환자에서 ACE1 변이체 및 ACE1/ACE2 발현 평가

Article

Published on 2022-02-012022-09-11
Journal: Vascular pharmacology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] ACE ACE1 ACE1 gene ACE1/ACE2 ACE2 ACE2 expression Affect allele angiotensinogen assessment association carrier carriers circulation Complication Control controls COVID-19 COVID-19 patient distribution ether examined expression expression level expression levels Expression. Frequency Genotype genotyped genotypes groups healthy controls I/D polymorphism ICU patient ICU Patients mRNA level non-ICU non-ICU patient non-ICU patients not different not significantly different p value Patient patients polymorphism Renin risk of COVID-19 significantly higher study groups total population transcripts two group two groups variant while
[DOI] 10.1016/j.vph.2021.106934 PMC 바로가기 [Article Type] Article

Anti-AT1R autoantibodies and prediction of the severity of Covid-19

항AT1R 자가항체와 코로나19 중증도 예측

Article

Published on 2022-02-012022-09-12
Journal: Human immunology [Category] COVID19(2023년), MERS, SARS, 진단,

Lactate and Lactate-to-Pyruvate Ratio in Critically Ill COVID-19 Patients: A Pilot Study

Article

Published on 2022-01-272022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

Peeking into a black box, the fairness and generalizability of a MIMIC-III benchmarking model

Article

Published on 2022-01-242022-10-04
Journal: Scientific Data [Category] 신약개발,

[키워드] black Care feedback loops Generalizability Health ICU Patients IMPROVE limitation medical ethics MONITOR overcome Patient performed Population raise required Research data resources risk while widespread
[DOI] 10.1038/s41597-021-01110-7 PMC 바로가기 [Article Type] Article

Regional Impact of COVID-19-Associated Pulmonary Aspergillosis (CAPA) during the First Wave

Article

Published on 2022-01-192022-10-30
Journal: Journal of Fungi [Category] COVID-19,

[키워드] 30-Day mortality Active surveillance acute respiratory distress all-cause mortality aspergillosis Biomarker CAPA Characteristics Clinical course Clinical outcome Cohort cohorts controls COPD Corticosteroids COVID-19 COVID-19 patient COVID-19 patients Critically ill diagnosing Evidence Factor fungal infections group highlight Host ICU ICU admission ICU Patients ICUs identify Impact incidence increase in intensive care patients intensive care unit invasive management mechanical ventilation mechanically ventilated medication multicentre Netherlands North not differ outcome Patient patients performed pulmonary pulmonary aspergillosis Regional renal replacement therapy required retrospective cohort study risk risk factor Risk factors SARS-COV-2 infection secondary severe COVID-19 patient significantly higher statistically significant syndrome Treatment outcome voriconazole Wave
[DOI] 10.3390/jof8020096 PMC 바로가기 [Article Type] Article

Awake prone positioning in nonintubated spontaneous breathing ICU patients with acute hypoxemic respiratory failure (PRONELIFE)—protocol for a randomized clinical trial

삽관되지 않은 자발 호흡 중환자 중 급성 저산소성 호흡 부전(PROONELIFE) 환자의 깨어 있는 엎드린 자세 - 무작위 임상 시험을 위한 프로토콜

Study Protocol

Published on 2022-01-102022-09-10
Journal: Trials [Category] 임상,

[키워드] Acute hypoxemic respiratory failure Acute respiratory failure all-cause mortality assigned Awake prone positioning benefit Blinding Clinical management clinical trial complications Composite consecutive patients Critically ill Critically ill patient critically ill patients determine duration of use Dyspnea Effect eligible Endpoint enrolment etiology hospital Hypoxemia hypoxemic Hypoxemic respiratory failure ICU ICU patient ICU Patients include International intubation intubation rate invasive invasive ventilation investigator-initiated ISRCTN lung tissue Mortality multicenter noninvasive respiratory Other Oxygenation parameters Patient Pragmatic Prevent primary endpoint Prone position prone positioning randomized clinical trial Randomized controlled trial Randomly reduction in reference number Registered respiratory Respiratory failure secondary Secondary endpoints spontaneous breathing standard care Support Tolerance tracheal tracheal intubation Trial Ventilation
[DOI] 10.1186/s13063-021-05991-2 PMC 바로가기 [Article Type] Study Protocol

Persistence of live virus in critically ill patients infected with SARS-COV-2: a prospective observational study

SARS-COV-2에 감염된 중환자에서 살아있는 바이러스의 지속성: 전향적 관찰 연구

Observational Study

Published on 2022-01-042022-09-11
Journal: Critical Care [Category] SARS, 임상, 치료기술,

[키워드] 95% CI AUC best Chain Reaction COVID-19 COVID-19 pneumonia Critically ill patient Culture cycle cycle threshold detect determine diagnosis of COVID-19 ICU admission ICU patient ICU Patients infection control infectiousness initial intensive care unit interquartile range lab lack Level 4 Live virus mechanical ventilation median nasopharyngeal nasopharyngeal sample Nasopharyngeal samples nasopharyngeal sampling non-infectious observational study Patient patients with COVID-19 PCR test performed polymerase chain polymerase chain reaction positive positive rate positive RT-PCR Positive test predict Prospective prospective observational study repeated Result reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR severity of illness specificity Test threshold Vero Cell Vero cells Viral viral culture Viral RNA were measured with COVID-19
[DOI] 10.1186/s13054-021-03884-z PMC 바로가기 [Article Type] Observational Study

SARS-CoV-2 N-antigenemia in critically ill adult COVID-19 patients: Frequency and association with inflammatory and tissue-damage biomarkers

중증 성인 COVID-19 환자의 SARS-CoV-2 N-항원혈증: 염증 및 조직 손상 바이오마커와의 빈도 및 연관성

Observational Study

Published on 2022-01-012022-09-11
Journal: Journal of medical virology [Category] SARS, 바이오마커, 임상, 치료기술, 치료법,

[키워드] 95% confidence interval absence adult COVID-19 patient antigenemia appear association Biomarker Biomarkers C-reactive protein Chain Reaction Clinical outcome Clinical severity Cohort collected COVID-19 COVID-19 patient Critically ill D-dimer ferritin ICU patient ICU Patients immunochromatography increased mortality Inflammation inflammation biomarkers Inflammatory Lactose lateral flow Logistic regression analysis median median age moderate Mortality Odds ratio parameter patients plasma Plasma levels polymerase chain polymerase chain reaction positive quantified quantitation recruited returned RNA RNA loads RT-PCR SARS-CoV-2 SARS-CoV-2 N protein SARS-CoV-2 N-antigenemia SARS-CoV-2 nucleocapsid SARS-CoV-2 RNA SARS-CoV-2 RNAemia Serum level serum levels significantly higher specimen symptoms onset tracheal aspirate Tracheal aspirates Univariate logistic regression analysis Viral Virological were measured were used yielding
[DOI] 10.1002/jmv.27300 PMC 바로가기 [Article Type] Observational Study

Acute Mesenteric Ischemia in COVID-19 Patients

Review

Published on 2021-12-302022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] Acute mesenteric ischemia adjust affected anticoagulant therapy Artery article association bowel C reactive protein COVID-19 COVID-19 patients CRP Cytokines duplication Endothelitis feature Fluid management help Hospitalized hospitalized COVID-19 patients hypercoagulability ICU Patients information intestinal involved Ischemia Laboratory Leukocytosis management mechanism Mesenteric Microvascular thrombosis offer outcome Pathways patients reported risk factor SARS-CoV-2 SARS-COV-2 infection surgery thromboemboembolism Thromboembolism Thromboprophylaxis understanding Vascular viability was performed Web of Science
[DOI] 10.3390/jcm11010200 PMC 바로가기 [Article Type] Review