Reduced COVID-19 mortality linked with early antibodies against SARS-CoV-2, irrespective of age연령에 관계없이 SARS-CoV-2에 대한 조기 항체와 연결된 COVID-19 사망률 감소Article Published on 2022-04-012022-09-11 Journal: European journal of internal medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료법, [키워드] Admission advanced age age Anti-spike antibody Antibody Response clinical assessment Clinical outcome co-morbidity Concentration COVID-19 COVID-19 infection COVID-19 mortality COVID-19 pandemic Cox regression model Critical death died discharged disease severity early phase early stage Efficiency elderly Elderly patient elderly patients functional healing hospital Hospital stay Hospitalization Humoral immunity IgG IgG levels IgM immune system Immunological response In-hospital death indicated lymphopenia modulate Mortality multivariate Multivariate Cox regression models Older outcome outcomes Patient produced PROTECT Protein risk risk factor SARS-CoV-2 serum Serum level serum levels stratified subject subjects therapeutic strategy titer [DOI] 10.1016/j.ejim.2022.02.010 PMC 바로가기 [Article Type] Article
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19SARS-CoV-2에 대한 T 세포 반응은 심각한 COVID-19에서 살아남은 환자에서 1년 후에도 지속됩니다Observational Study Published on 2022-04-012022-09-12 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adaptive alteration anti-SARS-CoV-2 anti-SARS-CoV-2 IgG characterized Claude Bernard concentrations convalescent COVID-19 patient COVID-19 patients Critically ill critically ill patients dependent on Diseases expression FIVE France HLA-DR hospice hospital discharge Hospital stay humoral immune response ICU IgG levels IL-10 IL-6 immune immune memory immune response individuals initial intensity lymphocyte lymphopenia memory monocyte HLA-DR Monocytes no difference Patient persist plasma robust SARS-CoV-2 SARS-CoV-2 antigens SARS-COV-2 infection Sepsis severe COVID-19 Severe patient subpopulations supported T cell proliferation T cell response T lymphocyte university [DOI] 10.1016/j.ebiom.2022.103967 PMC 바로가기 [Article Type] Observational Study
Clinical Characteristics of COVID-19 Patients’ Postvaccination코로나19 환자의 예방접종 후 임상적 특징Article Published on 2022-04-012022-09-11 Journal: Viral immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed approaches characteristic China clinical clinical characteristic Clinical characteristics collected Computed tomography conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CT findings demographic and clinical characteristics group groups IgG IgG antibodies IgG antibody IgG levels IgM implementation Infection information Laboratory no significant differences not affect not altered nucleic acid other variables outcome Patient respiratory SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 nucleic acid second dose severe acute respiratory syndrome Coronavirus significant difference temperature the median therapeutic approaches Thoracic Underscore vaccination Vaccination Status Vaccine vaccine dose Viral viral shedding [DOI] 10.1089/vim.2021.0204 PMC 바로가기 [Article Type] Article
Humoral and Cellular Immune Responses to SARS-CoV-2 mRNA Vaccination in Patients with Multiple Sclerosis: An Israeli Multi-Center Experience Following 3 Vaccine Doses다발성 경화증 환자의 SARS-CoV-2 mRNA 백신 접종에 대한 체액 및 세포 면역 반응: 3회 백신 접종 후 이스라엘의 다기관 경험Multicenter Study Published on 2022-04-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Affect Autoimmunity Blood BNT162b2 booster cell-mediated immune response cellular response Cellular responses Cladribine contribute COVID-19 disease Disease modifying therapies (DMTs) evaluated experience fingolimod Fingolimod- healthy control humoral Humoral response humoral responses IFNγ IgG IgG level IgG levels immune immune response immune responses incubated Longevity MOST mRNA mRNA vaccine Multiple multiple sclerosis Ocrelizumab Patient patients proportion recovering from COVID-19 recruited response SARS-CoV-2 secretion seropositive subgroup analysis T-cell T-cell immune response T-cell Response T-cell responses therapy time interval treated vaccination Vaccinations was collected were measured with COVID-19 within 6 months [DOI] 10.3389/fimmu.2022.868915 PMC 바로가기 [Article Type] Multicenter Study
Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose두 번째 백신 접종 후 180일 동안 의료 종사자(HW)에서 BNT162b 백신 2회 접종 후 세포 및 체액 면역 반응 및 돌발 감염Article Published on 2022-03-312022-09-12 Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, [키워드] age all subject binding antibody BNT162b Breakthrough infection Cytopathic effect Day Delta VOC Dilution domain enrolled evaluated groups healthcare Healthcare workers highest Hospitalization human serum humoral Humoral response identify IFN-γ IgG IgG level IgG levels IgG titer Immunity individuals Infection information Live virus long-lasting maintain microneutralization mRNA vaccine mRNA vaccines neutralized neutralizing antibody Neutralizing antibody titer neutralizing responses Neutralizing titer Older Predictive protective immunity Protein remained response SARS-CoV-2 second secretion shown stages subject subjects T-cell Response tested threshold Vaccine virus Volume was determined worker Wuhan strain [DOI] 10.3389/fpubh.2022.847384 PMC 바로가기 [Article Type] Article
Long-term longitudinal evaluation of the prevalence of SARS-CoV-2 antibodies in healthcare and university workers의료 및 대학 근로자의 SARS-CoV-2 항체 유병률에 대한 장기 종단 평가Article Published on 2022-03-252022-09-11 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed Asymptomatic contribute coronavirus Evolution Follow-up healthcare hospital IgA antibodies IgG IgG level IgG levels IgM IgM and IgG infections natural infection participant Participants pauci-symptomatic persistence positive Prevalence SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG serology seropositive participant severe acute respiratory syndrome Coronavirus sustained symptomatic tested [DOI] 10.1038/s41598-022-09215-8 PMC 바로가기 [Article Type] Article
Long-Term Antibody Response and Vaccination Efficacy in Patients with COVID-19: A Single Center One-Year Prospective Study from the Czech RepublicCOVID-19 환자의 장기 항체 반응 및 예방 접종 효능: 체코의 단일 센터 1년 전향적 연구Article Published on 2022-03-042022-09-11 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] Admission analyzed antibody Antibody Response Antibody responses antigen detection center characterized Cohort courses COVID-19 patient COVID-19 patients Czech Republic diagnosis of SARS-CoV-2 diagnostic disease Dynamics ELISA enrolled Evidence high correlation hospitalized patient hospitalized patients IgA IgG IgG antibodies IgG antibody IgG level IgG levels IgM and IgG indicated Infection Laboratory neutralization test Patient PCR performed positive positive antibody response positive antibody responses Prospective Prospective Study Reinfection response Sample SARS-CoV-2 SARS-COV-2 infection sensitivity serological data serology significantly specific antibodies specific antibody sustained the SARS-CoV-2 vaccination Virus neutralization virus neutralization test VNT [DOI] 10.3390/v14030526 PMC 바로가기 [Article Type] Article
Low transferrin levels predict heightened inflammation in patients with COVID-19: New insights낮은 트랜스페린 수치는 COVID-19 환자의 염증 증가를 예측합니다: 새로운 통찰력Article Published on 2022-03-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 바이오마커, [키워드] anti-SARS-CoV-2 antibodies association Biomarker Blood level blood levels C-reactive protein can be used COVID-19 CRP CRP levels cytokine Cytokine storm disease severity Evidence ferritin ferritin level ferritin levels hospitalized patient Hyperferritinemia hyperinflammation IgG levels IgM and IgG IL-6 ill patient immune increase in Inflammation Inflammatory interleukin interleukin 6 involved iron marker Mild Mounting New parameter Patient positive test result predict predicted progression SARS-CoV-2 serum Serum iron severe COVID-19 severity significant increase Symptom symptom severity test results the disease Transferrin Transferrin saturation. two group two groups Variation variations were measured [DOI] 10.1016/j.ijid.2021.12.340 PMC 바로가기 [Article Type] Article
Patients receiving hemodialysis do not lose SARS-CoV-2 antibodies more rapidly than non-renal controls: a prospective cohort study혈액 투석을받는 환자Report Published on 2022-02-282022-09-01 Journal: Renal failure [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults All participants ANOVA antibody both groups Cellular immune response cellular immunity comparable Control coronavirus coronavirus disease COVID-19 COVID-19 diagnosis declined disease onset evaluated General population greater HD group Hemodialysis humoral IgG IgG level IgG levels immune responses increased risk individual Infection Kidney disease Kidney function magnitude maintain Maintenance hemodialysis Mortality participant Patient patients treated prospective cohort study quantified receiving remained respiratory Result SARS-CoV-2 SARS-CoV-2 antibody seropositive Seropositivity severe acute respiratory syndrome Coronavirus significantly lower Specific T-cell response study period subgroup of patients T-cell Response T-cell responses [DOI] 10.1080/0886022X.2022.2042310 PMC 바로가기 [Article Type] Report
Longitudinal, virological, and serological assessment of hospitalized COVID-19 patients입원한 COVID-19 환자의 종단, 바이러스 및 혈청학적 평가Article Published on 2022-02-012022-09-11 Journal: Journal of Neurovirology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Admission anal swabs anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 IgM Antibody titers Blood blood sample Blood samples Cohort collected COVID-19 pandemic COVID-19 patient COVID-19 patients described discharge ELISA evaluated Evidence First wave healthcare Hospital admission Hospitalized hospitalized COVID-19 patient IgG antibody titer IgG antibody titers IgG levels IgM and IgG implication Italy longitudinal median time nasopharyngeal nasopharyngeal swabs Negative conversion NPs Patient patients positive provide qRT-PCR RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 RNA detection serological assessment seropositive serum sample serum samples significantly Swab tested the median Virological [DOI] 10.1007/s13365-021-01029-0 PMC 바로가기 [Article Type] Article