Immunomodulation by Mosquito Salivary Protein AgSAP Contributes to Early Host Infection by Plasmodium모기 침 단백질 AgSAP에 의한 면역 조절은 말라리아 원충에 의한 초기 숙주 감염에 기여한다.Research Article Published on 2021-12-142024-08-08 Journal: mBio [Category] 말라리아, [키워드] Anopheles immune regulation malaria Mosquito Plasmodium falciparum [DOI] 10.1128/mBio.03091-21 PMC 바로가기 [Article Type] Research Article
Pegylated Interferon-ɑ (IFN-ɑ) Enhances the Inhibitory Effect of Natural Killer Cells on Regulatory T Cells via IFN-γ in Chronic Hepatitis BArticle Published on 2021-12-012023-06-13 Journal: The Journal of Infectious Diseases [Category] B형 간염, [키워드] Chronic Hepatitis B IFN-γ immune regulation Natural killer cells regulatory T cells [DOI] 10.1093/infdis/jiab216
RNA-Seq Analysis of Influenza A Virus-Induced Transcriptional Changes in Mice Lung and Its Possible Implications for the Virus Pathogenicity in MiceArticle Published on 2021-10-082023-06-07 Journal: Viruses [Category] 신종인플루엔자, [키워드] cell cycle regulation immune regulation influenza A virus macrophages Prognosis [DOI] 10.3390/v13102031 PMC 바로가기 [Article Type] Article
Diversity of Macrophages in Lung Homeostasis and DiseasesImmunology Published on 2021-09-242022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, SARS, [키워드] alveolar macrophage Characteristics chronic lung diseases condition COVID-19 determine disease Diversity fibrosis function homeostasis immune regulation Infection Inflammation interstitial lung Lung disease Lung diseases Macrophage pathogen clearance physiological Population similarity unique [DOI] 10.3389/fimmu.2021.753940 PMC 바로가기 [Article Type] Immunology
Potential Adjuvant Therapeutic Effect of Lactobacillus plantarum Probio-88 Postbiotics against SARS-COV-2Article Published on 2021-09-242022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Lactobacillus plantarum adjuvant antiviral activity approach association binding binding affinity Cell conducted coronavirus COVID-19 COVID-19 pandemic develop drug Effect Efficacy effort ERK evaluated Helicase IFN-α IFN-β IL-6 immune regulation in silico in vitro indicated infected cells Infection Inflammatory Inflammatory marker inhibited lactobacillus Microbiome molecular docking pathogen plantaricin postbiotics Potential Prevent reactive oxygen specy reduction in Replication ROS SARS-CoV-2 severity significantly Spread tested Therapeutic approach treated Vaccine variants viral replication virus while [DOI] 10.3390/vaccines9101067 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolismSARS-COV-2 감염은 B- 세포 대사를 강화함으로써 B 세포에서 CD19 발현을 하향 조절함으로써 회수 된 환자에서 면역 결핍을 유발한다.Article Published on 2021-09-222022-08-31 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 바이오마커, 진단, [키워드] Adaptive immunity B cell B cells B-cell B-cell response BCR cause caused CD19 cell metabolism changed characterized COVID-19 downregulating dysregulation expression frequencies Frequency healthy control healthy controls immune Immune phenotype immune regulation immunodeficiency Immunological disorders Intervention memory B cell memory B cells metabolism Patient Population Recovered COVID-19 patients recovered patient recovered patients reduced SARS-COV-2 infection Signaling significantly significantly increased Stimulation subset [DOI] 10.1038/s41392-021-00749-3 PMC 바로가기 [Article Type] Article
Mesenchymal stem cell therapy for severe COVID-19Perspective Published on 2021-09-082022-10-04 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 바이오마커, 임상, 치료제, [키워드] acute respiratory syndrome acute SARS-CoV-2 infection adaptive caused Characteristics clinical trial conducted coronavirus coronavirus disease COVID-19 COVID-19 pandemic health authorities highlight immune disorder immune regulation immune tolerance IMPROVE Infectious diseases Inflammatory response innate immune responses lung damage mesenchymal stem cell MSC MSC therapy MSCs outbreak pathogenesis of COVID-19 Patient promote reduce regulate SARS-CoV-2 severe cases severe COVID-19 significantly stem cell Stem-cell research therapeutic therapeutic option therapy Treatment Virological [DOI] 10.1038/s41392-021-00754-6 PMC 바로가기 [Article Type] Perspective
Progress in Traditional Chinese Medicine Against Respiratory Viruses: A ReviewPharmacology Published on 2021-08-312022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome Against antiviral treatments arising basic theory of traditional Chinese medicine Chinese clearing heat and detoxication component components coronavirus COVID-19 disease drug resistance Host immune regulation Inflammation influenza A viruses mechanism of action Medicine Prevent Progress Research respiratory respiratory syncytial virus respiratory virus review SARS-CoV-2 synergistic targets TCM tissue Toxicity Traditional Traditional Chinese medicine Treatment unique virus growth viruses [DOI] 10.3389/fphar.2021.743623 PMC 바로가기 [Article Type] Pharmacology
Integrated human/SARS-CoV-2 metabolic models present novel treatment strategies against COVID-19통합된 인간/SARS-CoV-2 대사 모델은 COVID-19에 대한 새로운 치료 전략을 제시합니다Research Article Published on 2021-08-052022-09-10 Journal: Life Science Alliance [Category] MERS, SARS, 신약개발, [키워드] absence biochemical BioModel BioModels cause caused Cell cell death changes computational method coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 death drug target drugs entry of SARS-CoV-2 FDA-approved drug FDA-approved drugs function growth healthy human cell immune regulation mechanism New coronavirus pandemic pathogenic platform predict provide reaction required responsible SARS-CoV-2 Support Therapeutic strategies treatment strategy unique Viral viral entry [DOI] 10.26508/lsa.202000954 PMC 바로가기 [Article Type] Research Article
Changes in humoral immune response after SARS-CoV-2 infection in liver transplant recipients compared to immunocompetent patientsSARS-CoV-2 감염 후 면역적격 환자와 비교한 간이식 환자의 체액성 면역 반응 변화Multicenter Study Published on 2021-08-012022-09-11 Journal: American journal of transplantation : official jou [Category] SARS, 치료법, [키워드] 95% CI aldosterone angiotensin anti-Nucleocapsid IgG anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Case-control change clinical research/practice Control coronavirus disease Coronavirus disease 2019 COVID-19 evaluate female gender humoral immune response Humoral immunity immune immune modulation immune regulation Immunosuppressant Immunosuppression immunosuppression/immune modulation incidence Infection infection and infectious agents-viral infectious agents Infectious disease inhibitor levels of antibody liver liver transplant Liver transplantation liver transplantation/hepatology Lower multicenter Patient patients persistence Prevalence prognostic Propensity score Protective recipient recipients Renin renin-angiotensin-aldosterone system SARS-COV-2 infection serological data solid organ solid organ transplant therapy transplantation variable was performed [DOI] 10.1111/ajt.16599 PMC 바로가기 [Article Type] Multicenter Study