immunosuppressive – Page 4 – Communicable Diseases Research

Humoral and cellular response in convalescent COVID-19 lupus patients

회복기 COVID-19 루푸스 환자의 체액 및 세포 반응

Article

Published on 2022-08-122022-09-11
Journal: Scientific Reports [Category] SARS, 진단, 치료기술, 치료법, 치료제,

[키워드] accumulated adaptive Analysis analyzed antibodies antibody Antibody Response Antibody titer Antibody titers CD8 cellular response changes in collected confirmed cases confirmed COVID-19 case convalescent convalescent COVID-19 patient convalescent COVID-19 patients convalescent patient Convalescent patients COVID-19 COVID-19 disease COVID-19 incidence COVID-19 infection COVID-19 susceptibility declined decrease died dose dysregulation evaluated flow cytometry Gene expression analysis General population Health care higher risk Hospital admission humoral Humoral and cellular responses hypocomplementemia IgG antibodies immune dysregulation immune response immunological immunological profile Immunological studies Immunosuppression immunosuppressive immunosuppressive therapy impair incidence increase in Infection intensive care lack longitudinal longitudinal changes Lupus medical record memory cell Mild Patient patients PBMC PBMCs PCR-confirmed COVID-19 Prednisone predominant prospective cohort reduction required risk factor Risk factors SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody severe COVID-19 disease severe disease severity Signaling SLE Surveillance susceptibility sustained Symptom symptom onset T cell Th17 Th2 response therapy were measured
[DOI] 10.1038/s41598-022-17334-5 PMC 바로가기 [Article Type] Article

Persistent Fever and Positive PCR 90 Days Post-SARS-CoV-2 Infection in a Rituximab-Treated Patient: A Case of Late Antiviral Treatment

리툭시맙 치료 환자에서 SARS-CoV-2 감염 후 90일 동안 지속되는 발열 및 PCR 양성: 후기 항바이러스 치료 1례

Case Reports

Published on 2022-08-112022-09-11
Journal: Viruses [Category] SARS, 진단, 치료제,

[키워드] Antiviral treatment antivirals B cell B cell immune responses benefit Day defined diagnostic dominant Dyspnea early treatment feasible Fever full recovery high fever Hospitalized human long-term infection hyperinflammation Hypoxemia immune immune responses Immunocompromised Immunocompromised patients immunosuppressive immunosuppressive therapy infusion interval low-grade viral replication lower airway lower airways lung infiltrate lung infiltrates Mild mild to moderate moderate monoclonal monoclonal antibodies monoclonal antibody multiple sclerosis Patient patients PCR persistent persistent fever positive PCR test post infection Prophylactic receiving reduced reported Respiratory failure rituximab SARS-CoV-2 SARS-COV-2 infection sensitivity serum severe respiratory failure Symptom therapy Treatment treatment approach treatment approaches Viral viral replication
[DOI] 10.3390/v14081757 PMC 바로가기 [Article Type] Case Reports

Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infection

COVID-19 감염으로 면역저하된 소아 및 청소년에서 감염 및 혈청전환의 중증도를 예측하는 요인

Observational Study

Published on 2022-08-032022-09-12
Journal: Frontiers in Immunology [Category] SARS, 임상, 진단,

[키워드] Absolute lymphocyte count absolute neutrophil count Analysis ANC anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Antibody Response blood sample body mass index Cancer Cell Chemotherapy children Clinical severity comorbid condition COVID COVID 19 COVID-19 infection Critical Cutoff defined determine died Factor FIVE Hematologic malignancy Hematological malignancy high-risk population Hospitalized ICU Immunocompromised Immunocompromised patient immunosuppressive Infection Laboratory less Level lowest median moderate multivariable model observation outcome outcomes Patient patients PCR Pediatric patient predict Predictive receiving required Respiratory Support SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seroconversion seroconversion rate severity Severity of infection stem cell transplant steroid the patient therapy treated univariable vaccination variable was used with COVID-19
[DOI] 10.3389/fimmu.2022.919762 PMC 바로가기 [Article Type] Observational Study

Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases

급성 후 COVID-19는 염증성 장 질환에서 장 바이러스 항원 지속성을 특징으로 합니다

Article

Published on 2022-08-012022-09-11
Journal: Gastroenterology [Category] COVID19(2023년), SARS, 임상, 치료기술, 치료법,

[키워드] acute COVID-19 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Antigen biochemical CD8 Chain Reaction clinical trials Confirmed COVID-19 infection controlled clinical trials coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Culture detectable endoscopy enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated expression of SARS-CoV-2 flow cytometry globe Gut gut mucosa IBD immune immune response immunofluorescence immunosuppressive immunosuppressive therapy Inflammation Inflammatory bowel disease intestine investigated large intestine majority means Mild nucleocapsid nucleocapsid protein pandemic Patient performed persistence polymerase chain polymerase chain reaction populations Postacute COVID-19 Quantitative quantitative polymerase chain reaction questionnaire reported RNA SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severity Stool syndrome T cells therapy tissue Viral antigen Viral Antigen Persistence. viral nucleocapsid protein viral transcripts virus cultivation
[DOI] 10.1053/j.gastro.2022.04.037 PMC 바로가기 [Article Type] Article

Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy

면역억제 요법을 받는 환자에서 표준 및 3차 접종 SARS-CoV-2 백신 접종의 면역원성과 안전성

Observational Study

Published on 2022-08-012022-09-12
Journal: Arthritis & rheumatology (Hoboken, N.J.) [Category] COVID19(2023년), MERS, SARS, 임상, 진단,

[키워드] Adult patient adverse event age antibody arbitrary unit characterized combination therapy comparable Control controls defined disease dose evaluate facilitate full-length healthy healthy control healthy controls IgG antibody Immune-mediated inflammatory disease immunogenicity immunosuppressive inhibitor interquartile range jak inhibitors lowest median Necrosis Patient patient group patients performed predictor proportion prospective observational study psoriatic arthritis RBD receiving regimen Responder responders rheumatoid arthritis risk RNA-1273 Safe Safety safety profile SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serologic response Spike protein spondyloarthritis Standard Support the receptor-binding domain the SARS-CoV-2 therapy ulcerative colitis vaccination Vaccine vaccine dose vaccine response
[DOI] 10.1002/art.42153 PMC 바로가기 [Article Type] Observational Study

Predictors of seroconversion after coronavirus disease 2019 vaccination

코로나 바이러스 질병 2019 예방 접종 후 혈청 전환 예측자

Article

Published on 2022-08-012022-09-12
Journal: Annals of allergy, asthma & immunology : official [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] active malignancy acute respiratory syndrome age and sex antibody assay Antibody Response B cell Characteristics clinical Clinical characteristics Clinical data collected coronavirus coronavirus disease COVID-19 COVID-19 vaccination defined demographic Efficacy evaluate exhibited greater immunodeficiency immunosuppressants Immunosuppression immunosuppressive immunosuppressive drug lack likelihood Male sex men Older age pandemic Patient Primary Immunodeficiency receiving response SARS-CoV-2 Seroconversion seronegative patient Spike protein steroid the SARS-CoV-2 the vaccine therapy vaccination Vaccine were assessed women
[DOI] 10.1016/j.anai.2022.05.026 PMC 바로가기 [Article Type] Article

Humoral and cellular responses to mRNA-based COVID-19 booster vaccinations in patients with solid neoplasms under active treatment

Article

Published on 2022-08-012022-10-05
Journal: ESMO open [Category] 진단, 치료법,

[키워드] acute respiratory syndrome anti-spike antibody antibodies baseline BNT162b2 booster booster dose booster vaccination breakthrough infections Cancer cancer patient Cancer patients Care cause CD19+ CD4+ cell counts Cellular immune response cellular immunity cellular response Chemotherapy coronavirus COVID-19 COVID-19 infection died disease dose Efficacy Endocrine evaluated excluded exclusion criteria Factor Factors high risk high-risk population hospital humoral Humoral immunity immune response Immunosuppression immunosuppressive Infection Messenger RNA Mild mRNA mRNA vaccine mRNA-1273 mRNA-based neoplasm neutralizing antibody older patients Other outcome overcome Patient positive reduced required Result severe coronavirus disease significant increase significantly increased significantly lower solid malignancy solid tumors T-cell Response treated Treatment vaccination Vaccine vaccine dose Vaccines were assessed
[DOI] 10.1016/j.esmoop.2022.100587 [Article Type] Article

High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study

높은 바이러스 부하: 백신 접종자의 치명적인 COVID-19 사례를 유발하는 요인은 무엇입니까? - 부검 연구

Article

Published on 2022-08-012022-09-11
Journal: Modern pathology : an official journal of the Unit [Category] COVID19(2023년), SARS, 바이오마커, 변종, 임상, 진단, 치료기술, 치료법,

[키워드] accompanied analyzed Antibody-dependent enhancement Autopsies autopsy study Bacterial case study cause causes collected Comorbidities Comorbidity COVID-19 Ct-value Ct-values death Deceased determine died dissemination Factors histological immune system Immunoglobulin immunosuppressive immunosuppressive conditions individual Lungs malignancies Most patient Most patients Occurrence organ organ system organ systems Patient performed real-time RT-PCR RT-PCR RT-qPCR SARS-COV-2 infection SARS-CoV-2 infections significantly increased suffered upper airway upper airways vaccinated individuals vaccination Vaccine vaccinee vaccinees Viral viral loads viral spread Viral variants virus
[DOI] 10.1038/s41379-022-01069-9 PMC 바로가기 [Article Type] Article

Systemic sclerosis in the time of COVID-19

Review article

Published on 2022-08-012022-10-05
Journal: The Lancet Rheumatology [Category] 변종, 치료제,

[키워드] addition Antibody Response Cohort COVID-19 COVID-19 pandemic disease Effectiveness General population health-care immunosuppressive multiple organs outcome Patient patients treated physician recommendation reduced risk SARS-CoV-2 severe COVID-19 systemic Systemic sclerosis therapy Vaccine
[DOI] 10.1016/S2665-9913(22)00130-8 [Article Type] Review article

A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma

Case report

Published on 2022-08-012022-10-05
Journal: Journal of infection and chemotherapy : official j [Category] 변종, 치료법,