Resilience and Frailty in People Living With HIV During the COVID Era: Two Complementary Constructs Associated With Health-Related Quality of LifeObservational Study Published on 2022-02-012022-10-05 Journal: Journal of acquired immune deficiency syndromes (1 [Category] COVID19(2023년), SARS, 임상, [키워드] 95% confidence interval Affect age CD4 clinic clinical phenotype complementary Complete COVID COVID-19 crisis COVID-19 pandemic defined frailty HIV Impact Impaired life loneliness median age metabolic Modena offered phenotype Phenotypes PLWH positive Quality Quality of life questionnaire Questionnaires reached Resilience Sex stressors with HIV [DOI] 10.1097/QAI.0000000000002865 PMC 바로가기 [Article Type] Observational Study
Proposed mechanism for rare thrombotic events after use of some Covid-19 vaccinesResearch article Published on 2022-02-012022-10-05 Journal: Medical Hypotheses [Category] 변종, [키워드] Adenoviridae Adenovirus affected antibody binding caused Coagulation complex COVID-19 vaccines described DNA Factor X healthcare immune response Immunity Impaired impairment individuals mechanism Mutation offer option Platelet platelet activation PROTECT Protein stimulate thrombocytopenia thromboembolic complication Thromboembolic event thrombotic event Vaccine Vaccines Venous thrombosis virus [DOI] 10.1016/j.mehy.2021.110756 [Article Type] Research article
Impaired immune response to COVID-19 vaccination in patients with B-cell malignancies after CD19 CAR T-cell therapyCD19 CAR T 세포 치료 후 B 세포 악성 종양 환자에서 COVID-19 예방 접종에 대한 면역 반응 손상Article Published on 2022-01-252022-09-11 Journal: Blood advances [Category] SARS, 바이오마커, [키워드] B-cell malignancy CAR CD19 COVID-19 vaccination immune response Impaired Patient T-cell therapy [DOI] 10.1182/bloodadvances.2021006112 PMC 바로가기 [Article Type] Article
Impaired pulmonary ventilation beyond pneumonia in COVID-19: A preliminary observationCOVID-19에서 폐렴을 넘어 폐환기 장애: 예비 관찰Research Article Published on 2022-01-252022-09-12 Journal: PLoS ONE [Category] 진단, [키워드] abnormality accompanied Accuracy aetiology affected airway Analysis association asymptomatic patient asymptomatic patients baseline characteristic Clinical symptoms comparable coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 pneumonia CT scan CT scans diagnostic Diagnostic accuracy distribution Dyspnea dyspneic Entire lung functional group groups healthy control healthy controls heterogeneity hypoxia identify impair Impaired impairment lung median mild pneumonia nine observation Patient patients patients with COVID-19 pilot study Pneumonia provided Pulmonary function pulmonary ventilation R 2 radiological radiological feature radiological finding receiver receiver operating characteristic Result significantly Symptom symptomatic symptomatic patient Symptomatic patients Symptoms the patient Ventilation was used were assessed worsened [DOI] 10.1371/journal.pone.0263158 PMC 바로가기 [Article Type] Research Article
Mitochondrial Dysfunction Associates With Acute T Lymphocytopenia and Impaired Functionality in COVID-19 PatientsImmunology Published on 2022-01-142022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] acute phase acute respiratory syndrome Associate association Asymptomatic CD4 CD4 T-cell CD8 T cell CD8 T-cell convalescent coronavirus COVID-19 demonstrated Disease progression effector memory exhibited flow cytometry Frequency functional Hospital admission Hyperactivation Impaired impairment Infection Lower lymphocytopenia mechanism memory memory T cell Mild mitochondrial dysfunction mitochondrial dysfunction (MD) peptide phenotype proportion reduction SARS-CoV-2 Severe patient subject subset symptom onset symptomatic symptomatic patient T cell T cells T-cell T-cell functionality T-cell Response while [DOI] 10.3389/fimmu.2021.799896 PMC 바로가기 [Article Type] Immunology
Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemiaB 세포 만성 림프구성 백혈병 백신 접종 환자에서 SARS-CoV-2 델타 변이체 중화 장애Research Published on 2022-01-092022-09-10 Journal: Journal of Hematology & Oncology [Category] 변종, 진단, [키워드] Adenovirus adenovirus-based antibody Antibody Response Antibody responses B cell BTKi therapy CD20 Chronic lymphocytic leukaemia CLL CLL patient CLL patients control group controls COVID COVID-19 vaccination delta variant dominant dual failure functional Gender groups healthy controls healthy donor healthy donors immune protection Immune suppression Immunotherapy Impaired impaired antibody response impaired antibody responses indicate Leukaemia magnitude mRNA neutralisation Patient patient cohort post treatment Post-vaccine Predictive prophylactic antibiotics reduced respond responders responses Result risk SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection sera Seroconversion serum spike-specific antibody response stability supplementary material the SARS-CoV-2 titre titres Treatment vaccination Vaccine vaccine platform variant [DOI] 10.1186/s13045-021-01219-7 PMC 바로가기 [Article Type] Research
Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 PatientsArticle Published on 2022-01-012022-11-16 Journal: Journal of innate immunity [Category] 치료기술, [키워드] acute respiratory syndrome age antimicrobial peptide Cohort consequence COVID-19 COVID-19 patient COVID-19 patients Degradation described detectable detrimental DNase efficient clearance elderly elderly male extracellular DNA extracellular trap extracellular traps Factor Female patients fiber healthy controls higher risk Host identify Impaired inefficient Infection LL-37 male marker negative correlation NET NETs neutrophil Neutrophil extracellular traps occur Patient patients plasma potential risk reduced released risk severe COVID-19 thrombosis Thrombotic complications [DOI] 10.1159/000521594 PMC 바로가기
Impaired Folate-Mediated One-Carbon Metabolism in Type 2 Diabetes, Late-Onset Alzheimer’s Disease and Long COVID제2형 당뇨병, 후기 발병 알츠하이머병 및 장기 코로나에서 엽산 매개 단일 탄소 대사 장애Review Published on 2021-12-232022-09-10 Journal: Medicina [Category] SARS, 유전자 메커니즘, [키워드] Abnormalities Alzheimer’s disease Alzheimer’s disease biochemical Biomarker biosynthetic biosynthetic pathways carbon clinical disease COVID COVID-19 cytoplasm developmental diabetes Diabetes Mellitus Diseases elevated epigenetics folate functional homocysteine hyperhomocysteinemia Impaired incorporation knowledge Long Long COVID mechanism metabolic network metabolic pathway metabolic pathways metabolism Mitochondria MTHFR gene mutations nucleus nutritional B vitamin deficiencies PASC pathology pathway progression Repurposed drugs responsible SARS-CoV-2 Stress the reader Therapeutics Treatment Type type 2 diabete Type 2 diabetes mellitus Vitamin vitamins [DOI] 10.3390/medicina58010016 PMC 바로가기 [Article Type] Review
Effect of the COVID-19 outbreak and lockdown on mental health among post-secondary students in the Grand Est region of France: results of the PIMS-CoV19 studyResearch Published on 2021-12-152022-10-31 Journal: Health and Quality of Life Outcomes [Category] COVID-19, SARS, [키워드] affected age analyzed assist condition conditions conducted Coping strategy COVID-19 COVID-19 epidemic COVID-19 outbreak cross-sectional defined develop distress Effect Factor female France French French students healthy Hospitalization identify Impaired IMPROVE living conditions lockdown measure Mental mental health mental health concerns MOST participant Prevalence Result risk SF-12 sociodemographic data the mean was used [DOI] 10.1186/s12955-021-01903-9 PMC 바로가기 [Article Type] Research
Two Cases of Impaired Wound Healing Among Patients With Major Head and Neck Free-Flap Reconstruction in the Setting of COVID-19 InfectionOtolaryngology Published on 2021-12-012022-10-31 Journal: Cureus [Category] COVID-19, [키워드] wound healing acute respiratory syndrome affected change complications conditions coronavirus COVID-19 COVID-19 pandemic discharged Donor Effect flap free tissue transfer head Head and neck surgery healing Impaired Major microvascular reconstruction Neck operative Patient postoperative reconstruction required risk SARS-CoV-2 SARS-COV-2 infection Sepsis setting subsequent surgical the patient tissue transfer wound [DOI] 10.7759/cureus.20088 PMC 바로가기 [Article Type] Otolaryngology