IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function
Clinical Medicine
[키워드] 95% CI
ACE2
activate
activated
Activation
acute respiratory distress
analyzed
angiotensin-converting enzyme 2
autoantibody
Autoimmunity
Award
Biomarker
Blood
career
changes in
class-switching
clinical feature
Clinical outcome
complement
contribute
coronavirus SARS-CoV-2
COVID-19
demonstrated
development
disease
division
Donald
Effect
ELISA
Endothelial cell
endothelial function
expressed
foundation
functional
Gate
heart
Host immune response
identify
IgG
IgM
Implications
independent
initiated
Inpatients
Intramural
Jerome
Melinda Gate
NIH
Non-COVID-19
pathology
Patient
patients with moderate
receptor
recognizing
Result
rheumatology
SARS-COV-2 infection
Science
severe COVID-19
severe disease
syndrome
T cell
the SARS-CoV-2
therapeutic
undergo
Vascular
Vascular endothelium
ventilated patient
vessel
[DOI] 10.1172/jci.insight.158362 PMC 바로가기 [Article Type] Clinical Medicine
[DOI] 10.1172/jci.insight.158362 PMC 바로가기 [Article Type] Clinical Medicine