Stratifying the early radiologic trajectory in dyspneic patients with COVID-19 pneumoniaCOVID-19 폐렴을 가진 호흡곤란 환자의 초기 방사선 궤적 계층화Multicenter Study Published on 2021-10-222022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] 95% confidence interval Admission Algorithm Analysis baseline Care Characteristics Chest chest radiographs clinical Clinical findings confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Cox regression deep learning Dyspnea dyspneic elevated four groups group hazard ratio higher risk Hospitalization Inflammatory responses intensive care unit admission Laboratory material men mild pneumonia monitoring Mortality objective outcome Patient patients with COVID-19 Pneumonia quantified radiologic responses Result risk significantly more survival survival analysis symptom onset thrombocytopenia trajectory was performed was used [DOI] 10.1371/journal.pone.0259010 PMC 바로가기 [Article Type] Multicenter Study
Glucose-lowering drugs and outcome from COVID-19 among patients with type 2 diabetes mellitus: a population-wide analysis in Hong Kong제 2 형 당뇨병 환자의 포도당 저하 약물 및 Covid-19의 결과 : 홍콩의 인구 전체 분석Article Published on 2021-10-202022-08-31 Journal: BMJ Open [Category] MERS, SARS, 치료제, [키워드] 95% CI adjusted Admission adverse outcome age Analysis association baseline Clinical outcome Cohort Comorbidities Comorbidity Composite composite endpoint confirmed case confirmed cases COVID-19 Cox regression diabete diabetes diabetes & dipeptidyl peptidase Dipeptidyl peptidase-4 drug drugs endocrinology endocrinology. Endpoint Glucose Glucose-lowering drug Haemoglobin hazard health facilities Hong Kong In-hospital death incidence inhibitor inhibitors insulin intensive care intensive care unit admission Invasive mechanical ventilation median age men metformin multivariate multivariate Cox regression outcome Patient patients with diabete predict public health reduced retrospective cohort secondary outcome Sex smoking treated type 2 diabete type 2 diabetes user worse prognosis [DOI] 10.1136/bmjopen-2021-052310 PMC 바로가기 [Article Type] Article
The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children소아에서 과염증성 다기관 염증 증후군의 자가면역 시그니처Article Published on 2021-10-152022-09-11 Journal: The Journal of Clinical Investigation [Category] 바이오마커, 유전자 메커니즘, [키워드] Admission Analysis anti-Spike IgG antigenic antigens autoantibodies autoantibody autoantigen Autoimmune Autoimmune diseases Autoimmunity B cell BCR Cellular immune response children Cluster Coagulation coagulation pathways Combination complement contributing to COVID-19 Cytokines expressed Factor Genes heavy chain humoral immune responses Hyperinflammatory identify IgG IGHV immune immune responses Immunoglobulin Immunopathogenesis Inflammation inflammation markers Inflammatory Inflammatory response intensive care intensive care unit admission manifestation Mild MIS-C Multiorgan neutrophil neutrophil activation neutrophil response pathogenic pathway Patient Previous studies previous study proteomics receptor RNA sequencing SARS-COV-2 infection sequence Sequencing serum superantigen syndrome T cell T cell receptor TCR tissue damage TRBV11-2 Treatment Usage variable region [DOI] 10.1172/JCI151520 PMC 바로가기 [Article Type] Article
Invasive pneumococcal disease burden in hospitalized adults in Bogota, Colombia보고타, 콜롬비아에서 입원한 성인의 침습성 폐렴구균 질병 부담Research Published on 2021-10-122024-07-30 Journal: BMC Infectious Diseases [Category] 폐렴구균 감염증, [키워드] Hospitalization intensive care unit admission Invasive pneumococcal disease (IPD) Mortality Pneumococcal serotype distribution Prevalence Serotype replacement disease Streptococcus pneumoniae (Spn) [DOI] 10.1186/s12879-021-06769-2 PMC 바로가기 [Article Type] Research
Fulminant H1N1 and severe acute respiratory syndrome coronavirus-2 infections with a 4-year interval without an identifiable underlying cause: a case report전격성 H1N1 및 중증급성호흡기증후군 코로나바이러스-2 감염, 4년 간격으로 뚜렷한 근본 원인 없이: 증례 보고Case Reports Published on 2021-10-082022-09-10 Journal: Journal of Medical Case Reports [Category] MERS, SARS, 변종, 신종인플루엔자, [키워드] acute kidney acute respiratory syndrome Admission age Analysis Antiviral asymptomatic infection autoantibody Case report challenge clinical picture clinical recovery Comorbidity contributing to Coronavirus-2 Course COVID-19 demonstrated disease disease-causing enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Exome expression Factor fulminant genetic change Genetic changes genetic defect genetic defects Genetic variant genetic variants H1N1 H1N1 influenza healthy ICU immune immunological impairment indicate Infection infections Influenza intensive care intensive care unit admission interferon Interferon (INF) interferon pathway interferon response interferon-stimulated gene mechanical ventilation mononuclear cell mononuclear cells Pathways Patient Peripheral blood Perturbation reduced respiratory risk factor Risk factors SARS-CoV-2 Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity suffered susceptibility the interferon the patient triggered type I Variation Viral viral infection viral infections virus infection [DOI] 10.1186/s13256-021-03113-9 PMC 바로가기 [Article Type] Case Reports
Galectin-3 as prognostic biomarker in patients with COVID-19 acute respiratory failureCOVID-19 급성 호흡 부전 환자의 예후 바이오마커로서의 갈렉틴-3Observational Study Published on 2021-10-012022-09-11 Journal: Respiratory medicine [Category] MERS, 바이오마커, 임상, [키워드] 30-Day mortality acute respiratory distress syndrome Acute respiratory failure Admission Analysis ARDS arterial blood arterial blood gas Blood blood gas categorical variable chest X-ray Chi-square chi-square test Computed tomography consecutive patient continuous variable correlated COVID 19 COVID-19 disease Cox regression cut-off disease dosage endpoints enrolled Evidence evidence of Fisher Fisher's exact test fixed galactoside galectin-3 ICU increased risk Inflammation Inflammatory response intensive care unit intensive care unit admission Kaplan-Meier Kruskal-Wallis Kruskal-Wallis test Kruskal-Wallis tests Laboratory Laboratory test log-rank test Lung injury Mann-Whitney U Mortality no evidence of outcome Patient patients with COVID-19 performed Pneumonia predictive power predictor Primary outcome prognostic prognostic biomarker receiver receiver operating characteristic Regression respiratory respiratory distress Respiratory distress syndrome Respiratory failure risk routine secondary Secondary outcomes Serum level serum levels severe acute respiratory distress syndrome Stratification tested Viral Viral pneumonia were used with COVID-19 [DOI] 10.1016/j.rmed.2021.106556 PMC 바로가기 [Article Type] Observational Study
Outcomes of COVID-19 in Patients With Cancer: A Closer Look at Pre-Emptive Routine Screening Strategies암 환자의 COVID-19 결과: 선제적 정기 검진 전략 자세히 살펴보기Observational Study Published on 2021-09-012022-09-11 Journal: JCO oncology practice [Category] SARS, 임상, 치료기술, 치료제, [키워드] Absolute lymphocyte count acute respiratory syndrome Admission age all-cause mortality asymptomatic patient asymptomatic patients benefit Cancer center Chemotherapy clinical suspicion Cohort cohort of patient conducted coronavirus COVID-19 diagnosed diagnosed with COVID-19 FIVE groups Hospital admission Hospitalization independent predictor independent predictors Infection inpatient admission intensive care intensive care unit admission lymphocyte Mayo Clinic Mortality multisite multivariable analysis no significant differences not significantly different observational study Odds ratio outcome Patient Patients with cancer Primary outcome prospective observational study routine Screening secondary Secondary outcomes severe acute respiratory syndrome Coronavirus Strategy surgical therapy [DOI] 10.1200/OP.21.00177 PMC 바로가기 [Article Type] Observational Study
COVID-19 outcomes of 10,881 patients: retrospective study of neurological symptoms and associated manifestations (Philippine CORONA Study)Neurology and Preclinical Neurological Studies - Original Article Published on 2021-08-272022-10-29 Journal: Journal of neural transmission (Vienna, Austria : [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted hazard ratio adjusted odds ratio Associated symptom clinically cohort study conducted Confirmed COVID-19 infection COVID-19 COVID-19 patients critical cases determine Effect hospital Hospital admission hospitalized COVID-19 patient hospitalized patient ICU ICU admission increase Infection intensive care unit admission manifestation MCC Mild Mortality Neurological symptom New-onset neurological symptoms outcome Patient protocol Region Registration Respiratory failure retrospective Retrospective study risk Severe case severe cases significantly significantly higher significantly increased ventilator website with COVID-19 [DOI] 10.1007/s00702-021-02400-5 PMC 바로가기 [Article Type] Neurology and Preclinical Neurological Studies - Original Article
Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients2019년 한국인 환자의 갑상선 호르몬 프로필과 코로나바이러스 질병에 대한 예후적 영향Observational Study Published on 2021-08-012022-09-11 Journal: Endocrinology and metabolism (Seoul, Korea) [Category] MERS, 바이오마커, 임상, [키워드] 95% confidence interval Admission analyzed association change clinical Clinical data clinical outcomes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critical disease death Decreased disease disease severity dysfunction euthyroid Euthyroid sick syndromes evaluate evaluated followed by hazard ratio highest hormone Hormones Impact intensive care intensive care unit admission Korean lowest marker mechanical ventilation middle Mortality outcome Patient patients patients with COVID-19 profile Prognosis prognostic reported serum sick significantly lower South Korea suppression suppression of thyroid function syndrome Thyroid thyroid dysfunction thyroid function thyroid hormone Thyroid hormones thyroid stimulating hormone thyrotoxicosis triiodothyronine Triiodothyronine. TSH [DOI] 10.3803/EnM.2021.1109 PMC 바로가기 [Article Type] Observational Study
Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity외래 환자의 메트포르민 사용은 과체중 또는 비만 성인에서 COVID-19 질병의 중증도 감소와 관련이 있습니다.Article Published on 2021-07-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료제, [키워드] adjusted Admission age BMI body mass body mass index Chain Reaction clinics Cohort cohort analysis cohorts contribute coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 disease data set death decrease disease EHR EHR system Electronic health record Evidence evidence of exclusion criteria Health health record healthcare hemoglobin hospital Hospital admission Hospitalization inclusion criteria intensive care intensive care unit admission interleukin interleukin-6 lower mortality metformin morbidity Mortality Necrosis obesity observational studies observational study outcome Outpatient Patient polymerase chain polymerase chain reaction Polymerase chain reaction test positive primary care reduced Research SARS-CoV-2 severe COVID-19 disease severity of COVID-19 Treatment Tumor tumor-necrosis factor [DOI] 10.1002/jmv.26873 PMC 바로가기 [Article Type] Article