Epidemiology of pediatric uveitis and associated systemic diseasesResearch Article Published on 2021-04-012024-09-02 Journal: Pediatric Rheumatology Online Journal [Category] 대상포진, [키워드] antinuclear antibodies children HLA-B27 juvenile idiopathic arthritis [DOI] 10.1186/s12969-021-00516-2 PMC 바로가기 [Article Type] Research Article
Immune cartography of macrophage activation syndrome in the COVID-19 era코로나19 시대 대식세포 활성화 증후군의 면역 지도 촬영Review Published on 2021-03-012022-09-11 Journal: Nature reviews. Rheumatology [Category] SARS, 변종, 유전자 메커니즘, [키워드] adaptive alveolitis antigen receptor Arthritis Cancer Cancer immunotherapy cancers CAR Cell therapy chimeric antigen receptor complex interplay Connective tissue diseases continuum COVID-19 COVID-19 pneumonia Cytokine storm develop disease disparate dominant feature Gain Gain of function genetics Hyperinflammatory hypersensitivity immune immune function Immunity immunodeficiency immunological immunological disease immunothrombosis Implications in some Infection infectious innate and adaptive immunity innate immune juvenile idiopathic arthritis limit limits Macrophage macrophage activation syndrome MHC class MHC class II occur offer patients with COVID-19 Pneumonia provide responses second wave Sepsis severe inflammation Still T cell therapeutic therapy Trigger triggers type I interferon variant [DOI] 10.1038/s41584-020-00571-1 PMC 바로가기 [Article Type] Review
Comparative risk of infections among real-world users of biologics for juvenile idiopathic arthritis: data from the German BIKER registryarticle Published on 2021-02-162024-09-02 Journal: Rheumatology International [Category] 대상포진, [키워드] biologics infections juvenile idiopathic arthritis Safety [DOI] 10.1007/s00296-020-04774-3 PMC 바로가기 [Article Type] article
Early combination therapy with etanercept and methotrexate in JIA patients shortens the time to reach an inactive disease state and remission: results of a double-blind placebo-controlled trialResearch Article Published on 2021-01-062024-09-02 Journal: Pediatric Rheumatology Online Journal [Category] 대상포진, [키워드] juvenile idiopathic arthritis Remission TNF inhibitor [DOI] 10.1186/s12969-020-00488-9 PMC 바로가기 [Article Type] Research Article
Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19Article Published on 2020-12-072022-10-30 Journal: iScience [Category] COVID-19, [키워드] approach Bioactivity biological activity Blood clinical trial complement COVID-19 COVID-19 disease COVID-19 disease severity cytokine disease Effect elevated expression functional greater IL-1β IL-6 immunology immunomodulatory therapy immunopathology implicated Infection juvenile idiopathic arthritis Mortality nasopharynx Pathogenesis quantification reflect response rheumatoid arthritis severity of COVID-19 single gene therapeutic targeting tissue transcript transcriptional transcriptional response transcriptomics Virology [DOI] 10.1016/j.isci.2020.101896 PMC 바로가기 [Article Type] Article
Patients with juvenile idiopathic arthritis on TNF inhibitors exposed to COVID-19 family membersComment Published on 2020-12-012023-07-06 Journal: Seminars in arthritis and rheumatism [Category] SARS, [키워드] COVID-19 juvenile idiopathic arthritis rheumatic disease SARS-CoV-2 TNF inhibitor. [DOI] 10.1016/j.semarthrit.2020.09.012 PMC 바로가기 [Article Type] Comment
Management of Juvenile idiopathic arthritis-associated uveitis duringthe COVID-19 pandemic in a pediatric referral center in LombardyReview Published on 2020-11-162023-07-12 Journal: Ocular immunology and inflammation [Category] SARS, [키워드] COVID-19 JIA-associated uveitis juvenile idiopathic arthritis pediatric uveitis. SARS-CoV-2 [DOI] 10.1080/09273948.2020.1800752 [Article Type] Review
Long-term safety and effectiveness of etanercept in JIA: an 18-year experience from the BiKeR registryResearch Article Published on 2020-10-292024-09-02 Journal: Arthritis Research & Therapy [Category] 대상포진, [키워드] Biologics registry drug surveillance Etanercept JIA treatment juvenile idiopathic arthritis TNF inhibitors [DOI] 10.1186/s13075-020-02326-5 PMC 바로가기 [Article Type] Research Article
Biological and Clinical Changes in a Pediatric Series Treated with Off-Label JAK InhibitorsArticle Published on 2020-10-202024-09-02 Journal: International Journal of Molecular Sciences [Category] 대상포진, [키워드] interferon signature Janus kinase inhibitors juvenile idiopathic arthritis juvenile systemic erythematosus lupus juvenile systemic sclerosis monogenic interferonopathies off-label medications Pediatric rheumatology transcriptomics [DOI] 10.3390/ijms21207767 PMC 바로가기 [Article Type] Article
Translating IL-6 biology into effective treatments Reviews Published on 2020-04-232022-10-05 Journal: Nature reviews. Rheumatology [Category] SARS, 바이오마커, [키워드] anti-IL-6 receptor antibody production arteritis B cells condition COVID-19 Cytokine release syndrome disease Diseases dysregulation effective giant cell arteritis Health IL-6 IL-6 pathway immune regulation indications involved juvenile idiopathic arthritis pathway Pneumonia Research Rheumatic diseases rheumatoid arthritis secreted T cell targeting Therapeutic approach therapy Treatment [DOI] 10.1038/s41584-020-0419-z [Article Type] Reviews