Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, Indiaarticle Published on 2016-02-282024-09-01 Journal: Immunologic Research [Category] 말라리아, [키워드] Haplotype Linkage disequilibrium malaria polymorphism TLR2 family [Article Type] article
Uncovering the transmission dynamics of Plasmodium vivax using population geneticsarticle Published on 2015-05-312024-09-01 Journal: Pathogens and Global Health [Category] 말라리아, [키워드] Control Elimination genetic diversity genetics Genomics Linkage disequilibrium Malaria, Microsatellites mitochondrial DNA Plasmodium vivax Population structure Relapse single nucleotide polymorphisms Transmission [Article Type] article
Microsatellite markers reveal low levels of population sub-structuring of Plasmodium falciparum in southwestern Nigeria마이크로위성 마커는 나이지리아 남서부에서 플라스모디움 팔시파룸의 낮은 수준의 집단 하위 구조를 드러낸다.Research Published on 2014-12-132024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Genetic differentiation genetic diversity Linkage disequilibrium Plasmodium falciparum Population structure [DOI] 10.1186/1475-2875-13-493 PMC 바로가기 [Article Type] Research
Gene-Environment Dependence Creates Spurious Gene-Environment Interaction유전자-환경 의존성은 가짜 유전자-환경 상호작용을 생성한다Report Published on 2014-09-042022-08-07 Journal: American Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] Accuracy addition biological processe biological processes can not causal variant condition dependence disease epidemiological example gene-environment dependence gene-environment interaction genetic marker Genetic markers IMPROVE in addition to independent Interaction leads Linkage disequilibrium marker mediation no interaction Pleiotropy power risk Sample size shown SNP Spurious statistical interaction susceptible [DOI] 10.1016/j.ajhg.2014.07.014 PMC 바로가기 [Article Type] Report
Classic Selective Sweeps Revealed by Massive Sequencing in Cattle소에서 대규모 시퀀싱으로 밝혀진 클래식 선택적 스윕Research Article Published on 2014-02-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major affected affecting allele among others Analysis ancestors applied approach association autosomal SNP candidate gene cattle classic CLR complementary complexity Composite current detect detectable disequilibrium Domestication ERBB4 Evidence faster fixation Fleckvieh followed by Genetic genetics Genome genome-wide association genomic genomic region help homozygosity Human identify iHS IMPROVE KIT life style likelihood ratio linkage Linkage disequilibrium massive MC1R MITF multiple statistical metrics NRG4 overlap Perspective phenotype Phenotypes physical Protein QTL mapping QTLs Ratio re-sequencing Region regions Result Revealed score sensory perception Sequencing sequencing technology significantly somatic cell somatic cell count speciation subsequent TAS2R16 temper thought TMEM132D traits utility whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1004148 PMC 바로가기 [Article Type] Research Article
Single nucleotide polymorphisms of ADRB2 gene and their association with susceptibility for Plasmodium falciparum malaria and asthma in an Indian populationarticle Published on 2013-12-312024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] ADRB2 Asthma Haplotype Linkage disequilibrium malaria SNP [Article Type] article
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinationsMHC 지역 내의 유전적 변이는 어린이 예방 접종에 대한 면역 반응성과 관련이 있다.journal-article Published on 2013-11-012024-07-30 Journal: Vaccine [Category] 백일해, 파상풍, [키워드] Childhood vaccine CPS diphtheria, tetanus, and pertussis DTaP Genetic polymorphism haemophilus influenza type b HBsAg HBV Hepatitis B virus heptavalent pneumococcal conjugate HIB HLA human leukocyte antigen IG immune response Immunoglobulin Inactivated polio vaccine IPV LD Linkage disequilibrium major histocompatibility complex MHC Odds ratio OR PCV7 pneumococcal cell wall polysaccharide pneumococcal polysaccharides PnPS Single nucleotide polymorphism SNP Surface antigen of hepatitis B virus. [DOI] 10.1016/j.vaccine.2013.09.026 [Article Type] journal-article
Local population structure of Plasmodium : impact on malaria control and elimination말라리아 통제 및 제거에 대한 영향: 플라스모디움의 지역 인구 구조Research Published on 2012-12-112024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Linkage disequilibrium malaria control Microsatellites Plasmodium Population structure recrudescence [DOI] 10.1186/1475-2875-11-412 PMC 바로가기 [Article Type] Research
The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition GrooveHLA 클래스 I 항원 인식 그루브와 관련된 중국 비인두암의 주요 유전적 결정인자Research Article Published on 2012-11-292022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele allele frequencies alleles Amino acid Analysis analyzed antigens association associations Author binding Cancer carcinoma carried China Chinese chromosome chromosome 6 class Cohort concert dependent on detect detected determinant disease driven by EBV epithelial Epstein-Barr virus examined facilitated GABBR1 Gene gene region genetic influence Genome-wide association study Groove Guangdong Guangxi GWAS HCG9 help High-resolution HLA HLA alleles HLA class I HLA class I gene HLA region HLA-A HLA-A and -B HLA-B HLA-F incidence independent Infection influences influences on Interaction involved large cohort Linkage disequilibrium malignancy molecular motif multivariate Nasopharyngeal carcinoma NPC nucleotide operative OR2H1 over peptide performed physically principal Recognition recognize Region regression analysis replicate Replication resolved risk second sequence SNP SNPs statistical study participant the major histocompatibility the strongest variant variants virus infection [DOI] 10.1371/journal.pgen.1003103 PMC 바로가기 [Article Type] Research Article
A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci6개의 1형 당뇨병 코호트에 대한 게놈 전체 메타 분석으로 여러 관련 유전자좌 식별Research Article Published on 2011-09-292022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] ADCY3 affected association Author C6orf120 CENPO chromosomal combined cohort contributing to controls dataset diabete diabetes disease DLL1 DNAJC27 DNMT3A domain EFR3B examined excess FAM120B Follow-up Gene gene network gene networks Genes Genetic genetic component genetic loci genetic screening Genome Genome-wide association studies Genome-wide association study genome-wide significance genotyped GWAS homolog hypotheses identify Impact independent intergenic region intronic region investigator investigators Linkage disequilibrium LMO7 LOC154449 loci meta-analyses Meta-analysis Multiple NCOA1 Pathogenesis PHF10 POMC Protein PSMB1 reached recent finding Region replicated risk risk for disease significantly SNP SNPs susceptibility T1D TBP the disease Type Type 1 diabetes variant variants WDR27 [DOI] 10.1371/journal.pgen.1002293 PMC 바로가기 [Article Type] Research Article