Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 VaccinesReview Published on 2021-11-172022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acute respiratory syndrome adjuvants antigens application cause Characteristics compounds COVID-19 effective hydrophilic immune response Infection infections Infectious disease Influenza investigated Liposome liposomes Lower lower airways Lower respiratory tract LRT lung Nanoparticles pandemic of COVID-19 recent respiratory respiratory syncytial virus RSV SARS-CoV SARS-CoV-1 SARS-CoV-2 scientist tract unique Vaccine Vaccine development Vaccines viral infection viruses [DOI] 10.3390/ph14111173 PMC 바로가기 [Article Type] Review
DNA‐Directed Patterning for Versatile Validation and Characterization of a Lipid‐Based Nanoparticle Model of SARS‐CoV‐2SARS -COV -2의 지질 기반 나노 입자 모델의 다목적 검증 및 특성화를위한 DNA 방향 패터닝Research Article Published on 2021-10-212022-08-31 Journal: Advanced Science [Category] MERS, SARS, 변종, 진단, 치료제, [키워드] a glass ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin applied assays benefit bind binding biological function CD63 Cell characterization complementary oligonucleotide complementary oligonucleotides coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 demonstrated DNA‐directed patterning Efficacy encapsulation enzyme flexible glass hybridized Liposome liposomes mixture Model nanoparticle Neutralizing antibodies neutralizing antibody offer oligonucleotide oligonucleotides Population power Precision Protein Region respiratory SARS‐CoV‐2 SARS‐CoV‐2 spike SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus spike subsequent substrate surface proteins Vaccine validation variants variety virus [DOI] 10.1002/advs.202101166 PMC 바로가기 [Article Type] Research Article
The investigation of mRNA vaccines formulated in liposomes administrated in multiple routes against SARS-CoV-2SARS-CoV-2에 대한 다중 경로로 투여되는 리포솜에 제형화된 mRNA 백신의 조사Article Published on 2021-07-102022-09-12 Journal: Journal of controlled release : official journal o [Category] SARS, 진단, [키워드] administration Administration route Affect cellular immune responses COVID-19 Efficacy and safety Express global public health immunized mice in vivo indicated Intramuscular injection investigated Lipid nanoparticle Liposome liposomes LNP mice mRNA mRNA vaccine mRNA vaccines neutralized neutralizing capacity pandemic Prevent public health crisis RBD Receptor-binding domain safety profile SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudotyped virus SARS-CoV-2 RBD SARS-CoV-2 vaccine sera specific antibody Th2-type Vaccine virus [DOI] 10.1016/j.jconrel.2021.05.024 PMC 바로가기 [Article Type] Article
A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challengeBiological Sciences Published on 2021-06-012024-09-04 Journal: Proceedings of the National Academy of Sciences of [Category] 대상포진, [키워드] adjuvant cobalt porphyrin influenza vaccine liposomes nanoparticle vaccine [DOI] 10.1073/pnas.2025759118 PMC 바로가기 [Article Type] Biological Sciences
HBV Pre-S1-Derived Myristoylated Peptide (Myr47): Identification of the Inhibitory Activity on the Cellular Uptake of Lipid NanoparticlesArticle Published on 2021-05-172023-06-02 Journal: Viruses [Category] B형 간염, [키워드] apolipoprotein E (ApoE) cellular uptake HBV surface antigen (HBsAg) Hepatitis B virus (HBV) liposomes Myr47 lipopeptide sodium taurocholate cotransporting polypeptide (NTCP) [DOI] 10.3390/v13050929 PMC 바로가기 [Article Type] Article
Aerosolized nanoliposomal carrier of remdesivir: an effective alternative for COVID-19 treatment in vitro렘데시비르의 에어로졸화된 나노리포솜 담체: 시험관 내 COVID-19 치료에 대한 효과적인 대안Research Article Published on 2021-05-132022-08-31 Journal: Nanomedicine [Category] 치료제, [키워드] A549 A549 cell A549 cells Abstract Administered aerosol approved bloodstream calu-3 cells cells Characteristics Complete coronavirus disease Coronavirus disease 2019 COVID-19 cytotoxicity demonstrated Desirable drug drug delivery effective Efficacy Efficiency encapsulation ENhance evaluated fraction hospital in vitro indicated injection Liposome liposomes localized treatment lung lung adenocarcinoma Lungs median monolayer integrity nebulizer Particle pulmonary Remdesivir required retained Side effects stability sustained Treatment [DOI] 10.2217/nnm-2020-0475 PMC 바로가기 [Article Type] Research Article
Methodical Design of Viral Vaccines Based on Avant-Garde Nanocarriers: A Multi-Domain Narrative ReviewReview Published on 2021-05-062022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] approach caused compounds Corona Coronavirus 2019 COVID-19 Degradation different diseases drug delivery generate Health immune responses lipid particles liposomes long-lasting management nanoliposomes narrative nucleic acids other molecules outbreak pathogen peptides Protective review SARS-CoV-2 target cells the vaccine theranostics tocosome Vaccine Vaccine design Viral diseases virus [DOI] 10.3390/biomedicines9050520 PMC 바로가기 [Article Type] Review
Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity헤마글루티닌 기능화 리포솜 백신은 배아 중심 및 여포 도우미 T 세포 면역을 강화합니다Article Published on 2021-05-012022-09-12 Journal: Advanced Healthcare Materials [Category] SARS, 진단, [키워드] Antigen B cell center draining lymph nodes driving effective vaccine elicit follicular follicular helper T cells Germinal Germinal center germinal centers helper helper T cell hemagglutinin highly pathogenic HIV immunization immunogen Influenza influenza vaccines Influenza virus life-threatening Liposome liposomes mice microfluidic mixers nanoparticle-based vaccines. pathogen Protective Protein provide public health reported responses Safe SARS-CoV-2 serum antibody Subunit vaccine subunit vaccines Toxicity Vaccine Vaccines virus [DOI] 10.1002/adhm.202002142 PMC 바로가기 [Article Type] Article
Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 VaccinesReview Published on 2021-04-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] approval Cancer carriers clinic clinical clinical trials COVID-19 COVID-19 vaccine COVID-19 vaccines Doxil highlight immunotherapies Immunotherapy Lipid nanoparticle Lipid nanoparticles liposomes nanomedicine nanomedicines nanoparticle physicochemical property Regulatory required Research therapeutic Vaccine Vaccines [DOI] 10.3390/vaccines9040359 PMC 바로가기 [Article Type] Review
Optimization and evaluation of propolis liposomes as a promising therapeutic approach for COVID-19COVID-19에 대한 유망한 치료 접근법으로서 프로폴리스 리포솜의 최적화 및 평가Article Published on 2021-01-052022-09-11 Journal: International journal of pharmaceutics [Category] SARS, 치료제, [키워드] 3CL-protease anti-viral activity Antiviral approach Avigan caffeic acid comparable component COVID-19 determined by develop Docking studies docking study Efficiency encapsulation highest affinity Hydroxychloroquine IC50 inhibitory effect injection Liposome liposomes methodology optimization parameter Particle performed Propolis protease Protein released Remdesivir response Result RT-PCR rutin significantly spike Spike protein targets Therapeutic approach Treatment Viral viral replication [DOI] 10.1016/j.ijpharm.2020.120028 PMC 바로가기 [Article Type] Article