Mass COVID-19 patient screening using UvsX and UvsY mediated DNA recombination and high throughput parallel sequencingUVSX 및 UVSY 매개 DNA 재조합 및 높은 처리량 병렬 시퀀싱을 사용한 질량 COVID-19 환자 스크리닝Article Published on 2022-03-082022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] 2019 novel coronavirus 2019-nCoV Amplicon amplicons amplification approach Bioinformatics analysis Community Containment coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient detect develop DNA downstream fatigue Fever foundation Generation Genome High-throughput screening Illumina include individuals Infection Isolation isothermal life-threatening mass Mediated Medical conditions Molecular assay molecular assays non-infectious Novel coronavirus Patient per day platform protocol REcombinase Recombination REMBRANDT respiratory respiratory symptom RNA virus SARS-CoV-2 Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Shortness of breath Symptom Symptomatic patients [DOI] 10.1038/s41598-022-08034-1 PMC 바로가기 [Article Type] Article
Positive Effects of an Online Workplace Exercise Intervention during the COVID-19 Pandemic on Quality of Life Perception in Computer Workers: A Quasi-Experimental Study DesignArticle Published on 2022-03-072022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] ANOVA applied benefit Chronic diseases computer conditions control group COVID-19 COVID-19 pandemic decrease determine Diagnosis domain Effect evaluate the effect exclusion criteria exercise function Health health condition help high risk inclusion criteria intensity Interaction Intervention intervention group less life Medical conditions occupational health online exercise programme participant Perception performance performed physical positive Quality Quality of life questionnaire SF-36v2 socio-demographic Stage stages survey telework was obtained was used were used Workplace [DOI] 10.3390/ijerph19053142 PMC 바로가기 [Article Type] Article
Comparison of Early and Late Intubation in COVID-19 and Its Effect on MortalityArticle Published on 2022-03-052022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] Affect age baseline clinical Cohort Comorbidities Comorbidity conducted Course COVID-19 COVID-19 patient determine Effect emergency department Endotracheal intubation Gender greater hospital information Intubated intubation management median Medical conditions Mortality mortality rate noninvasive Patient patient mortality performed positive COVID-19 qSOFA required Respiratory failure retrospective smoking status statistically significant statistically significant difference two group was collected [DOI] 10.3390/ijerph19053075 PMC 바로가기 [Article Type] Article
Short-term effectiveness of COVID-19 vaccines in immunocompromised patients: A systematic literature review and meta-analysisReview article Published on 2022-03-012022-10-05 Journal: The Journal of Infection [Category] SARS, 변종, 진단, [키워드] 95% CI anti-SARS-CoV-2 antibody production calculated control group controls COVID-19 COVID-19 infection COVID-19 mRNA vaccine COVID-19 vaccine Diagnosis diagnostic effective Effectiveness groups healthy IgG IgG antibody Immunocompromised Immunocompromised patient Immunocompromised patients Inflammatory investigated laboratory-confirmed literature review malignant disease Medical conditions Meta-analysis much higher objective Odds ratio Prevent Research Result rheumatic disease solid organ transplant Spike protein stratified symptomatic [DOI] 10.1016/j.jinf.2021.12.035 [Article Type] Review article
Healthy Immunity on Preventive Medicine for Combating COVID-19Review Published on 2022-02-272022-10-31 Journal: Nutrients [Category] COVID-19, [키워드] acute respiratory syndrome advance aging and underlying medical conditions antioxidants approaches Asymptomatic binding biological processe caused cellular structures combating complications coronavirus Coronavirus disease 2019 COVID-19 deficiency disease enzyme events Gender genomic genomic variants Health healthy help Host host cell Host–pathogen interaction immune health immune responses immune system Immunity immunomodulation include Infection Infectious disease management Medical conditions medication Medicine men micronutrients Minerals molecular morbidity Mortality multifactorial nutrition Occurrence organs outcomes Pathogenesis pathogenesis of COVID-19 Pathogens Pathologies physiological activities populations Prevent preventive measure proteomic receptors regulated SARS-CoV-2 severe symptoms Sex signaling molecules Therapeutic strategies treat unique vaccination variety vitamins with COVID-19 women [DOI] 10.3390/nu14051004 PMC 바로가기 [Article Type] Review
SMART COVID Navigator, a Clinical Decision Support Tool for COVID-19 Treatment: Design and Development StudyOriginal Paper Published on 2022-02-182022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Affect aggregate analyzed approach assist cancer tissue caused clinical clinical decision Clinical decision support clinician collected comprehensive view condition conditions connection COVID COVID-19 COVID-19 progression data set decision determine development disease Electronic health record examined fatality FHIR Health health information identify individual infected with COVID-19 information Interaction interoperability likelihood medical condition Medical conditions objective observational study outcome outcomes Patient patient’s medical history patients with COVID-19 physician precision medicine predict Probability produced progression Research research finding Result SARS-CoV-2 severity severity of COVID-19 Support tissue treat Treatment Volume web application with COVID-19 [DOI] 10.2196/29279 PMC 바로가기 [Article Type] Original Paper
The Impact of COVID-19 on Routine Medical Care and Cancer Screening일상적인 의료 및 암 검진에 대한 COVID-19의 영향Original Research Published on 2022-01-102022-09-10 Journal: Journal of General Internal Medicine [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] 95% CI Anxiety Appointment approach approaches association Cancelled Cancer Cancer screening Care changed conducted COVID-19 cross-sectional survey death rate deaths demographics Depression depressive depressive symptom Depressive symptoms determine Ethnicity Factor help identify Impact income intolerance Local magnitude measure Medical care medical condition Medical conditions mental health missed medical appointments mitigate objective outreach participant Patient plan proportion race relationship Result risk routine Screening strongly related supplementary material Support understanding unmet need [DOI] 10.1007/s11606-021-07254-x PMC 바로가기 [Article Type] Original Research
Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients외래 환자에서 중증 코로나19로의 진행을 예방하기 위한 조기 렘데시비르Randomized Controlled Trial Published on 2021-12-222022-09-25 Journal: The New England Journal of Medicine [Category] Fulltext, SARS, 신약개발, 임상, 진단, 치료제, [키워드] 95% CI 95% confidence interval Adverse adverse event age assigned Clinical outcome condition conducted coronavirus disease Course death Diabetes Mellitus died Disease progression dose double-blind efficacy end point end point EudraCT event hazard ratio high risk Hispanic Hospitalization hypertension IMPROVE Intravenous remdesivir Latinx lower risk Medical conditions obesity occurred Outpatient Patient patients hospitalized Placebo placebo-controlled trial Prevent progression randomization Randomized Randomly receive Remdesivir Result risk factor safety profile symptom onset symptomatic the patient the placebo group women [DOI] 10.1056/NEJMoa2116846 PMC 바로가기 [Article Type] Randomized Controlled Trial
Analysis of COVID-19 Vaccine Type and Adverse Effects Following VaccinationResearch Published on 2021-12-222022-10-29 Journal: JAMA Network Open [Category] COVID-19, SARS, [키워드] 95% CI Adverse adverse effect adverse effects age allergic reaction Analysis anaphylaxis BNT162b2 candidate Cohort cohort study comparison Complete COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine dose drug Effect evaluate events exposure Factor female finding greater Health Importance include independent individual IQR JNJ-78436735 Johnson & Johnson measure mechanism median Medical conditions Moderna mRNA-1273 mRNA-1273 vaccine multivariable logistic regression objective Odds ratio of BNT162b2 Older participant Pfizer/BioNTech Point provided Relevance reported Result Science serious COVID-19 setting severity Sex Substance use Surveillance Type vaccination Vaccine vaccine dose with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.40364 PMC 바로가기 [Article Type] Research
Hydroxyzine Use and Mortality in Patients Hospitalized for COVID-19: A Multicenter Observational StudyArticle Published on 2021-12-152022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95%CI Administered adults hospitalized Analysis anti-inflammatory properties antiviral activity AOR association Characteristics COVID-19 daily dose death Effect FIASMA functional high risk Hospital admission Hospitalization hydroxyzine individual Inpatients median Medical conditions medication medications Mortality mortality rate multicenter multicenter observational study multiple sensitivity analyses multivariable logistic regression Outpatient Patient patients hospitalized placebo-controlled Prophylaxis randomized clinical trial reduced retrospective SARS-CoV-2 severe COVID-19 Treatment [DOI] 10.3390/jcm10245891 PMC 바로가기 [Article Type] Article