miRNA – Page 4 – Communicable Diseases Research

Induction of Hypoxic Response in Caco-2 Cells Promote the Expression of Genes Involved in SARS-CoV-2 Endocytosis and Transcytosis

Article

Published on 2022-10-012022-11-16
Journal: Doklady. Biochemistry and biophysics [Category] COVID19(2023년), SARS, 유전자 메커니즘,

Expression analysis of miRNA hsa-let7b-5p in naso-oropharyngeal swabs of COVID-19 patients supports its role in regulating ACE2 and DPP4 receptors

Article

Published on 2022-10-012022-11-15
Journal: Journal of Cellular and Molecular Medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘,

The SARS-CoV-2 targeted human RNA binding proteins network biology to investigate COVID-19 associated manifestations

Article

Published on 2022-09-302022-10-04
Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제,

3’UTR of SARS-CoV-2 spike gene hijack host miR-296 or miR-520h to disturb cell proliferation and cytokine signaling

Article

Published on 2022-09-272022-11-16
Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘,

Therapeutic prospects of ceRNAs in COVID-19

Article

Published on 2022-09-202022-11-15
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 치료제,

MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies

MiRNA-SARS-CoV-2 대화 및 전향적인 항-COVID-19 치료법

Review

Published on 2022-09-152022-09-11
Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 비임상, 진단, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adverse effect adverse effects Affect antiviral response approach approved Biomarker caused Cell signaling chance Clinical significance Comorbidities coronavirus Coronavirus-2 country COVID-19 COVID-19 illness COVID-19 infection COVID-19 pathogenesis COVID-19 patient Critical death detect differential expression disease disease onset disease pathology effort etiology expression FDA focus Host host cell host inflammatory response host miRNA host miRNAs identify Infection life cycle microRNA miRNA miRNAs molecular interaction non-coding RNA offer pathogen Pathogen-host interaction patients with COVID-19 post-transcriptionally quest reduce respiratory respond RNA RNA silencing SARS Coronavirus SARS coronavirus 2 SARS coronavirus 2. SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity Signaling target gene the SARS-CoV-2 virus therapy treat Treatment Viral viral miRNA viral miRNAs
[DOI] 10.1016/j.lfs.2022.120761 PMC 바로가기 [Article Type] Review

IFI44 is an immune evasion biomarker for SARS-CoV-2 and Staphylococcus aureus infection in patients with RA

Article

Published on 2022-09-152022-11-15
Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] 1,25-dihydroxy vitamin D3 activated acute respiratory syndrome analyses Analysis applied autoimmune conditions Bacteremia Bacterial Bacterial infection Bacterial infections Bioinformatics analysis Biomarker caused Cell cell membrane CIBERSORT conducted coronavirus COVID-19 Cytoscape database dataset datasets DEGs dendritic cell dendritic cells dendritic cells. differentially expressed differentially expressed gene disease DNA drug target Effectiveness examined expression FIVE functional enrichment Functional enrichment analysis GBP1 gene network GeneMANIA Genes global pandemic HERC5 humans identify Ifi44 IFI44L IFIT3 IFIT5 IFN signaling IFN signaling pathway IFN-α/β Immune cell infiltration immune cells Immune escape immune evasion immune system Immunological response Infection infections infiltration Intersection ISG15 KEGG mechanism miRNA molecular mechanism molecular target NLR OAS1 oxidative phosphorylation pathogenic bacteria pathway Patient platform positive correlation PPI network prevalent proliferation promote regulate Regulation Rheumatoid rheumatoid arthritis risk factor ROC curves RSAD2 Rtp4 SARS-CoV-2 SARS-COV-2 infection severe coronavirus disease signaling pathway Staphylococcus Staphylococcus aureus target the SARS-CoV-2 therapeutic viral infection viral replication virus were used YY1
[DOI] 10.3389/fimmu.2022.1013322 PMC 바로가기

Single cell gene expression profiling of nasal ciliated cells reveals distinctive biological processes related to epigenetic mechanisms in patients with severe COVID-19

Research article

Published on 2022-09-012022-10-05
Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 신약개발, 유전자 메커니즘, 임상,

[키워드] Activation addition analyses biological processe Cell cellular chromatin ciliated cell Clinical course COVID-19 disease DNA downregulation Epigenetic epithelial cell expand explain Gene expression profiling gene expression signature healthy control histone methylation Histones Interaction mechanism mechanisms membrane permeability Methylation miRNA misfolded proteins Mitochondria Mitochondrial function molecular nasal nasopharyngeal objective pathogenic mechanism pathway enrichment Patient patients with COVID-19 Regulation Regulatory Result reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 miRNAs scRNAseq sequence severe COVID-19 Single-cell RNA sequencing Single-cell transcriptomics the patient upregulation were used
[DOI] 10.1016/j.compbiomed.2022.105895 [Article Type] Research article

Dysregulated miRNAs network in the critical COVID-19: An important clue for uncontrolled immunothrombosis/thromboinflammation

중요한 COVID-19에서 조절되지 않는 miRNA 네트워크: 통제되지 않는 면역혈전증/혈전염증에 대한 중요한 단서

Review

Published on 2022-09-012022-09-11
Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술,

[키워드] accompanied activated Activation adenine affecting anti-inflammatory factors Anticoagulant cause clinical complication Coagulation Coagulation system complement complement system Complication components conserved coronavirus disease Coronavirus disease 2019 COVID-19 Critical Cytokine storm Defensive mechanism deviation diffusion Effect expression expression level facilitate Factor function Genetic higher risk homeostasis hyperinflammation immune immunothrombosis incidence Interaction involved life-threatening mechanism microRNA MicroRNAs miRNA miRNAs miRNAs-based therapy. molecules Mortality NADPH nicotinamide nicotinamide adenine dinucleotide Nicotinamide adenine dinucleotide phosphate Non-coding RNAs nucleotide oxygen Pathogens Patient phosphate reactive oxygen species reactive oxygen specy reduction response restrict SARS-CoV-2 severe complications Therapeutic approach therapy Thromboinflammation thrombotic underlie vicious cycle
[DOI] 10.1016/j.intimp.2022.109040 PMC 바로가기 [Article Type] Review

Contrasting Distribution of SARS-CoV-2 Lineages across Multiple Rounds of Pandemic Waves in West Bengal, the Gateway of East and North-East States of India

Article

Published on 2022-08-312022-11-16
Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종,