A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-2Original Article Published on 2021-06-242022-10-30 Journal: Molecular Therapy. Nucleic Acids [Category] COVID-19, [키워드] Abstract ALISA Antigen aptamer batch-to-batch variation binding biochemical characterized clinical evaluation comparable COVID-19 demonstrated detect detection diagnostic diagnostics DNA G-quadruplex health emergency in silico individual management Nasopharyngeal swab nasopharyngeal swab specimen non-infected outbreak PROTECT Protein SARS-CoV-2 SARS-CoV-2 infected individual Sensitivity and specificity spike trimer trimeric unmet need utility vaccinate Variability virus widespread [DOI] 10.1016/j.omtn.2021.06.014 PMC 바로가기 [Article Type] Original Article
Assay System for Simultaneous Detection of SARS-CoV-2 and Other Respiratory VirusesArticle Published on 2021-06-132022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory syndrome Analysis automated can be used caused comparable coronavirus coronavirus disease detection diagnostic disease Efficiency FIVE help Inc. Infection infections Influenza virus molecular nasopharyngeal swab specimen no significant difference nonspecific nucleic acid extraction Other overlap pandemic Patient platform processed reliability respiratory respiratory infection respiratory syncytial virus respiratory virus RSV SARS-CoV-2 Simultaneous simultaneous detection South Korea statistically Symptom System Trigger viral strain Z-scores [DOI] 10.3390/diagnostics11061084 PMC 바로가기 [Article Type] Article
How to choose the right real-time RT-PCR primer sets for the SARS-CoV-2 genome detection?Short Communication Published on 2021-05-242022-11-01 Journal: Journal of virological methods [Category] COVID-19, SARS, [키워드] binding Clinical performance clinically coding region comparable contribute COVID-19 COVID‐19 diagnosed diagnostic European false negatives genetic diversity Genome help in silico analysis Laboratory limitation molecular molecular detection nasopharyngeal swab specimen nucleocapsid nucleotide objective Patient performed polymerase chain primer set public health Public health interventions Quantitative RdRP Real-time RT PCR real-time RT-PCR Result reveal RNA-dependent RNA polymerase RT-qPCR SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 RNA detection SARS-CoV-2 sequence sensitivity sequence target region the SARS-CoV-2 genome US CDC variants of concern viral loads World Health Organization [DOI] 10.1016/j.jviromet.2021.114197 PMC 바로가기 [Article Type] Short Communication
Complete Genome Sequence of a SARS-CoV-2 Strain Sampled in Morocco in May 2020, Obtained Using Sanger SequencingGenome Sequences Published on 2021-05-202022-10-29 Journal: Microbiology Resource Announcements [Category] COVID-19, [키워드] acute respiratory syndrome amino acid substitution clade Complete coronavirus coronavirus disease COVID-19 female genome sequence Morocco Mutation nasopharyngeal swab specimen Patient Rabat SARS-CoV-2 strain was obtained [DOI] 10.1128/MRA.00387-21 PMC 바로가기 [Article Type] Genome Sequences
Development of an immunochromatographic kit to detect severe acute respiratory syndrome coronavirus 2Short Communication Published on 2021-05-112022-10-04 Journal: Journal of virological methods [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome alternative method assays collected Concentration coronavirus Coronavirus disease-19 Coronavirus disease-19 (COVID-19) Coronavirus-2 COVID-19 COVID-19 patient detect develop development diagnosed Diagnosis diagnosis of COVID-19 Diagnostic method evaluated Genetic HCoV-229E HCoV-OC43 human coronavirus immunochromatographic immunochromatographic assay Immunochromatographic kit MERS-CoV Middle East monoclonal antibody nasopharyngeal swab specimen OC43 pandemic pathogen Patient point-of-care Protein Rapid respiratory infections respiratory syndrome coronavirus responsible Result RT-PCR SARS-CoV-2 SARS-CoV-2 nucleocapsid severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) swab specimen symptom onset the N protein virus were used [DOI] 10.1016/j.jviromet.2021.114183 PMC 바로가기 [Article Type] Short Communication
Distinguishing non severe cases of dengue from COVID-19 in the context of co-epidemics: A cohort study in a SARS-CoV-2 testing center on Reunion islandResearch Article Published on 2021-04-262022-10-28 Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval 95%CI absence Analysis Anosmia attack rates Bahamas circulating clinically cohort study conducted confidence Contact controls Coronavirus 2019 country COVID-19 dengue virus diagnosed diagnostic distinguishing eligible Epidemics epidemiological Factor febrile handling headache Healthcare system Healthcare systems help highlight hospital identify illness illnesses independent predictor Infection infections interval less Mild Moderate COVID-19 multinomial logistic regression nasopharyngeal swab specimen nine orientation test outbreak over Pain pathogen peaking performed plague polymerase positive predictor questionnaire respiratory responsible retrospective cohort study reverse transcription SARS-CoV-2 SARS-CoV-2 testing screened Severe case similarity smoking study period subject Symptom symptom onset symptomatic These data university upper respiratory tract were assessed with COVID-19 wrought [DOI] 10.1371/journal.pntd.0008879 PMC 바로가기 [Article Type] Research Article
ABO blood type association with SARS-CoV-2 infection mortality: A single-center population in New York CityClinical Trial Published on 2021-04-012022-10-05 Journal: Transfusion [Category] SARS, 임상, [키워드] ABO ABO blood type acute respiratory syndrome all-cause mortality rate analyzed association Blood calculated Clinical course competing coronavirus COVID-19 COVID-19 patient COVID-19 patients Cox proportional hazard criteria cumulative death discharge hazard ratio Immunity In-hospital death in-hospital mortality incidence include individual inquiry mechanism mortalities Mortality multivariable nasopharyngeal swab specimen New York City nucleic acid test Patient patients hospitalized performed positive test result risk SARS-CoV-2 SARS-COV-2 infection single-center study cohort study inclusion subsequent suggested susceptibility tested Type [DOI] 10.1111/trf.16339 PMC 바로가기 [Article Type] Clinical Trial
Genome Sequences of Three SARS-CoV-2 P.1 Strains Identified from Patients Returning from Brazil to ItalyGenome Sequences Published on 2021-03-252022-10-29 Journal: Microbiology Resource Announcements [Category] COVID-19, [키워드] acute respiratory syndrome Brazil Complete coronavirus coronavirus disease COVID-19 Identified Italy nasopharyngeal swab specimen P.1 pandemic Patient SARS-CoV-2 sequence strain [DOI] 10.1128/MRA.00177-21 PMC 바로가기 [Article Type] Genome Sequences
First Report of a SARS-CoV-2 Genome Sequence with a Spike His69-Val70 Deletion and an Asn439Lys Mutation in MoroccoGenome Sequences Published on 2021-03-182022-10-29 Journal: Microbiology Resource Announcements [Category] COVID-19, [키워드] acute respiratory syndrome collected Complete coronavirus Deletion described Genetic variation genome sequence Ion male Morocco nasopharyngeal swab specimen Patient report SARS-CoV-2 sequence spike was obtained [DOI] 10.1128/MRA.00027-21 PMC 바로가기 [Article Type] Genome Sequences
Frequency of asymptomatic carriers of SARS-CoV-2 among children and adults after school reopening등교 개학 후 어린이와 성인의 SARS-CoV-2 무증상 보균자 빈도Research Published on 2021-03-122022-09-10 Journal: Italian Journal of Pediatrics [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome coronavirus adult subject Adults Asymptomatic Asymptomatic carrier Asymptomatic carriers asymptomatic form calculated carrier children conducted coronavirus coronavirus 2 cross-sectional cross-sectional study Department develop eligible Emergency emergency department enrolled females Frequency higher risk Infection Italy median age Nasopharyngeal swab nasopharyngeal swab specimen new SARS-CoV-2 observation Odds ratio Patient pediatric positive reopening respiratory Result risk SARS-CoV-2 SARS-COV-2 infection School Schools severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread Symptom tested the SARS-CoV-2 variants [DOI] 10.1186/s13052-021-01016-5 PMC 바로가기 [Article Type] Research