Emerging cases of mucormycosis under COVID-19 pandemic in India: Misuse of antibioticsObservational Study Published on 2021-11-012022-10-05 Journal: Drug development research [Category] 임상, [키워드] accounted addition Antibiotics Black fungus caused corticosteroid treatment COVID-19 COVID-19 case COVID-19 pandemic deaths Diabetic disease dropped drug First wave fungal Fungal infection glucocorticoid High dose Hypoxemia immune immunosuppressive India maintain Mild misuse Mucormycosis neutropenia pathway poor prognosis recorded reported risk factor SARS-CoV-2 second wave Spread stability Steroids Tocilizumab treated uncontrolled [DOI] 10.1002/ddr.21862 PMC 바로가기 [Article Type] Observational Study
Impact of the COVID-19 Pandemic on Survival in the Patients With the Intra-Abdominal InfectionsMedicine Published on 2021-10-202022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acquisition Admission age Analysis analyzed Care changes in Clinical outcome clinical variable Cohort collected Comorbidity conducted Contact coronavirus disease COVID-19 COVID-19 pandemic death death rate diagnosed Diagnosis E. coli Effect Escherichia coli extension Factor had more homogeneous hospital hospital discharge Immunosuppression Impact independent Infection Intervention intra-abdominal infection Mortality Multivariate analysis neutropenia pandemic Patient patients performed prospective observational cohort required Sepsis Septic shock Severe infection Sex significantly higher Spain Support surgery surgical symptoms onset the patient time interval university [DOI] 10.3389/fmed.2021.687415 PMC 바로가기 [Article Type] Medicine
COVID-19 in multiple-myeloma patients: cellular and humoral immunity against SARS-CoV-2 in a short- and long-term view다발성 골수종 환자의 코로나19: 단기 및 장기 관점에서 SARS-CoV-2에 대한 세포 및 체액 면역Case Reports Published on 2021-10-182022-09-10 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] MERS, SARS, 진단, 치료기술, [키워드] Affect affecting anti-SARS-CoV-2 antibody antibody levels Antibody titer Antibody titers CD4+ T-cell cell activation cellular Cellular immune response Clinical management Combination Continuous Course COVID-19 Decision-making deficiency detectable diagnosed with COVID-19 Disease progression help humoral Humoral immunity Hypogammaglobulinemia IgA IgG antibodies IgM IgM and IgG immune response Immunity immunodeficiency immunological immunomodulatory drugs Immunosuppression infections information inhibitors Innate immunity Isolation lenalidomide Measures memory monoclonal antibodies monoclonal antibody Multiple Multiple myeloma Myeloma neutralizing antibody titers neutropenia Patient performed positive proteasome receiving recommendation remained robust SARS-CoV-2 supplementary material supportive therapy T cell T cell activation T-cell tested the patient therapy treated Treatment underlying disease virus-neutralizing virus-neutralizing antibody [DOI] 10.1007/s00109-021-02114-x PMC 바로가기 [Article Type] Case Reports
Cytokine Response to SARS-CoV-2 Infection in Children소아의 SARS-COV-2 감염에 대한 사이토 카인 반응Article Published on 2021-09-182022-09-10 Journal: Viruses [Category] SARS, 바이오마커, [키워드] affected analyzed assigned children circulating clinical Clinical and laboratory data Clinical studies connection control group control groups COVID-19 COVID-19 group COVID-19 severity cytokine cytokine levels Cytokines Department disease severity Diseases Emergency emergency department evaluate feature IL-6 Immune-mediated immunological Infection infections Infectious diseases laboratory data lymphocyte Lymphocyte count lymphocyte counts Nasopharyngeal swab neutropenia no difference other infectious diseases pathogenicity patients pediatric predict recruited response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections serum biomarker serum biomarkers serum levels severity of COVID-19 Symptom tested three groups TNF-α TNF-alpha [DOI] 10.3390/v13091868 PMC 바로가기 [Article Type] Article
Clinical characteristics of COVID-19 in neonates and young infants신생아와 영유아에서 코로나19의 임상적 특징Article Published on 2021-09-012022-09-11 Journal: European journal of pediatrics [Category] SARS, 치료기술, [키워드] age Characteristics clinical Clinical characteristics COVID-19 COVID-19 in neonate disease hypertriglyceridemia Infant Infants Laboratory lymphopenia management Mild Mild disease Mild symptom mild symptoms monocytosis Neonate neutropenia pandemic prolonged viral shedding radiological risk factor SARS-CoV-2 severe COVID-19 specific treatment Transient Transmission with COVID-19 [DOI] 10.1007/s00431-021-04042-x PMC 바로가기 [Article Type] Article
A Multicenter Analysis of the Outcome of Cancer Patients with Neutropenia and COVID-19 Optionally Treated with Granulocyte-Colony Stimulating Factor (G-CSF): A Comparative AnalysisArticle Published on 2021-08-202022-10-31 Journal: Cancers [Category] COVID-19, [키워드] 95% CI adjusted advanced disease affected age Analysis analyzed association Cancer cancer patient carried clinical collected Comparative covariates COVID-19 COVID-19 outbreak curative Cytokine storm death develop distress Evidence Factor G-CSF G-CSF treatment higher risk Host Hyperinflammatory Infection infection with COVID-19 Logistic lowest lung management Mortality multicenter multivariable analysis multivariable logistic regression neutropenia neutrophil non-randomized outcome outcomes P -value parameter parameters Patient patients treated performed predict Probability Respiratory failure retrospective SARS-CoV-2 SARS-COV-2 infection screened severity Sex significant effect simple Stimulating Support syndrome treated Treatment was obtained was related were used with COVID-19 [DOI] 10.3390/cancers13164205 PMC 바로가기 [Article Type] Article
Autoimmune neutropenia associated with influenza virus infection in childhood: a case reportCase Report Published on 2021-08-182022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, [키워드] antibody Autoimmune neutropenia Blood Case report characterized childhood children Conservative management cough Course diagnosed disorder etiology Fever hematological Infant Infection influenza infection Influenza virus life-threatening male management mutations nasopharyngeal neutropenia Neutrophils performed positive Rapid test reported severe infections subsequent the disease Treatment triggered underlying conditions viral infection [DOI] 10.1186/s12879-021-06506-9 PMC 바로가기 [Article Type] Case Report
Case Report: Remdesivir and Convalescent Plasma in a Newly Acute B Lymphoblastic Leukemia Diagnosis With Concomitant Sars-CoV-2 InfectionPediatrics Published on 2021-08-022022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] accelerate Acute lymphoblastic leukemia adverse event age antiviral therapy Blood Bone marrow Cancer Chest clinical conditions Concomitant convalescent plasma COVID-19 diagnosed Diagnosis disease female Fever Hypothesis Immunosuppressive treatment Infection infections leukemia malignancies management moderate molecular analysis Morphological neutropenia oncology patients Patient pediatric Prognosis pulmonary involvement Remdesevir required risk SARS-CoV-2 detection SARS-COV-2 infection SARS–CoV−2 severe SARS-CoV-2 Spread stability therapy Treatment worsened [DOI] 10.3389/fped.2021.712603 PMC 바로가기 [Article Type] Pediatrics
Liver transplant in a recently COVID-19 positive child with hepatoblastoma간모세포종을 가진 최근 COVID-19 양성 아동의 간 이식Case Reports Published on 2021-08-012022-09-12 Journal: Pediatric transplantation [Category] MERS, 진단, [키워드] antibody block clearance clinical Course COVID-19 Diagnosis discharge home disease Disease progression hepatoblastoma highlight IgG and IgM Immunosuppression initial liver liver transplant Liver transplantation male neutropenia NP swab Patient pediatric pediatric liver transplantation performed positive Prednisone product real-time RT-PCR regimen remained resolution of symptom risk SARS- CoV-2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG antibody SARS-CoV-2 RT-PCR Test therapy viral infection with COVID-19 [DOI] 10.1111/petr.13880 PMC 바로가기 [Article Type] Case Reports
Connecting the Dots: Interplay of Pathogenic Mechanisms between COVID-19 Disease and MucormycosisReview Published on 2021-07-292022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] acquisition addition caused Cell contribute contributing to Corticosteroid corticosteroid therapy corticosteroid treatment country COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patients Diabetes Mellitus Diabetic disease EGFR endothelial epithelial cells explain expression Factor Factors growth GRP78 haematological malignancies Host iatrogenic immune dysfunction India induce innate immune function Interaction Invasion iron Mucorale Mucorales Mucormycosis neutropenia pancrea Pathogenesis Patient patients with diabete phagocytic cell receptor reduce reported risk solid organ transplants spore therapy tropical virulence virus-induced endothelial dysfunction [DOI] 10.3390/jof7080616 PMC 바로가기 [Article Type] Review