peripheral – Page 4 – Communicable Diseases Research

Effects of IFIH1 rs1990760 variants on systemic inflammation and outcome in critically ill COVID-19 patients in an observational translational study

관찰 중개 연구에서 중환자 COVID-19 환자의 전신 염증 및 결과에 대한 IFIH1 rs1990760 변이체의 효과

Research Article

Published on 2022-01-212022-09-10
Journal: eLife [Category] 변종,

Protocol for SARS-CoV-2 post-vaccine surveillance study in Australian adults and children with cancer: an observational study of safety and serological and immunological response to SARS-CoV-2 vaccination (SerOzNET)

SARS-COV-2 호주 성인 및 암 소아에서의 산후 감시 연구 프로토콜 : SARS-COV-2 백신 접종 (Seroznet)에 대한 안전 및 혈청 학적 및 면역 학적 반응에 대한 관찰 연구 (Seroznet)

Study Protocol

Published on 2022-01-202022-09-10
Journal: BMC Infectious Diseases [Category] SARS, 변종, 임상,

[키워드] acceptability adverse event adverse events allergy Analysis Blood Cancer Cancer patients Characteristics Chemotherapy children clinical clinical trial clinical trials cohorts collected commenced comparable condition controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 vaccinations COVID-19 vaccine COVID-19 vaccines disease manifestation effective enrolled exploration FIVE haematological malignancy healthy healthy control healthy controls HM patient HM patients hypogammaglobulinaemia Immune checkpoint inhibitor Immune checkpoint inhibitors immune correlate immune correlates immune response Immunity Immunocompromise Immunological response Immunosuppression immunosuppressive condition immunosuppressive conditions incidence Infection less life malignancy morbidity and mortality naïve New observational study organ pandemic coronavirus Patient Patients with cancer peripheral Peripheral blood Polysorbate polysorbate 80 populations Post-vaccine pre-vaccination processed proportion prospective observational study Quality question receiving reducing Registered Registration registry reported required robust SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serologic response serologic responses serological serological response severe COVID-19 SOC solid organ supplementary material Surveillance systemic therapy T-cell therapy timepoint Toxicity Treatment Trial unique vaccination Vaccinations Vaccine Vaccine hesitancy vaccine response variants virus were excluded
[DOI] 10.1186/s12879-021-07019-1 PMC 바로가기 [Article Type] Study Protocol

B- and T-Cell Responses After SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis Receiving Disease Modifying Therapies: Immunological Patterns and Clinical Implications

Clinical Trial

Published on 2022-01-172022-10-04
Journal: Frontiers in Immunology [Category] 임상, 치료기술,

[키워드] acute respiratory syndrome administration age and sex All the patient Analysis anti-S anti-S antibody Antibody detection Antibody titers B-lymphocyte blood lymphocyte count CD20 cell-mediated response characterized circulating clinical Cohort comparable coronavirus Coronavirus-2 correlation COVID COVID-19 disease dose effective enrolled evaluate fingolimod General population GraphPad Prism healthy donor help Humoral response IFN-gamma IGRA Immunological response increase in lymphocyte Modifying mRNA vaccine Multiple multiple sclerosis Natalizumab NK-cell Ocrelizumab Patient pattern peptide peptides peripheral Peripheral blood Population protective role raised reduced reduction reported response Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine sclerosis second dose severe COVID-19 Spread symptoms of COVID-19 T-cell T-cell Response T-cell responses T-lymphocyte Treatment Vaccination strategy Vaccine vaccine immunogenicity was performed were assessed while
[DOI] 10.3389/fimmu.2021.796482 PMC 바로가기 [Article Type] Clinical Trial

Inflammatory laboratory findings associated with severe illness among hospitalized individuals with COVID-19 in Medan, Indonesia: a cross-sectional study

Research Article

Published on 2022-01-142022-10-31
Journal: F1000Research [Category] COVID-19, MERS, SARS,

[키워드] 24 hour acute respiratory distress Admission Analysis Blood BMI body mass index C-reactive protein (CRP Characteristics comorbid Comorbidities Comorbidity Comparative conducted COVID-19 COVID-19 patient COVID-19 vaccination Critical Critically ill cross-sectional CRP cytokine Cytokine storm D-dimer diabete disease enzyme Factor good health groups Health higher risk Hospitalized ICU IFN-gamma IL-10 IL-6 increase indicated individuals with COVID-19 Inflammatory Inflammatory cytokine inflammatory markers inflammatory parameter Inflammatory response intensive care interferon Laboratory laboratory result Lipase Liver function MCP-1 men monocyte chemoattractant protein-1 Most patient Necrosis NLR obesity pancrea parameters peripheral renal function serum electrolyte severe COVID-19 severe COVID-19 patient severe pneumonia severity of COVID-19 Sex significant difference significantly higher subject syndrome the cytokine storm TNF-alpha vaccination Well-being were assessed
[DOI] 10.12688/f1000research.74758.2 PMC 바로가기 [Article Type] Research Article

New Translational Trends in Personalized Medicine: Autologous Peripheral Blood Stem Cells and Plasma for COVID-19 Patient

Case Report

Published on 2022-01-102022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

[키워드] acute respiratory distress Allograft ARDS arterial blood gas (ABG) autologous autologous plasma and peripheral blood stem cells benefit Blood caused clinical biochemistry and molecular clinical biology Clinical stages Community coronavirus 2 country COVID-19 COVID-19 infection COVID-19 pandemic Critical death deaths disease effective Health Health authority ICU Inconclusive individual infected patient intensive care unit involved Italy Laboratory medicine MOF mortality rate multiple organ failure New Patient peripheral Peripheral blood plasma Protective antibody protocol reported respiratory SARS-CoV-2 Sepsis specific treatment STEM stem cell stem cells survivor Survivors syndrome the vaccine therapeutic Therapies thromboembolic to define Treatment trend Vascular
[DOI] 10.3390/jpm12010085 PMC 바로가기 [Article Type] Case Report

Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19

혈전증 관련 순환 miR-16-5p는 COVID-19로 입원한 환자의 질병 중증도와 관련이 있습니다

Article

Published on 2022-01-012022-09-11
Journal: RNA Biology [Category] 바이오마커,

[키워드] 95% CI ACE2 ACE2 receptor activated acute respiratory syndrome acute respiratory syndrome coronavirus Admission amyloid amyloid beta Analysis angiotensin Angiotensin-converting enzyme app approach Area baseline baseline expression Beta bioinformatic analysis bioinformatics Bioinformatics analysis Biomarker Blood Blood cells body mass CALM1 calmodulin can be used changes in chronic obstructive circulating class Co-expression analysis Coagulation composite endpoint condition Control Coronary artery coronavirus coronavirus disease Coronavirus infection COVID-19 COVID-19 complications COVID-19 patient cyclin dataset death diabete diabetes Diabetes Mellitus diagnostic disease disease severity EGFR ELAVL1 enzyme expression expression level expression levels expressions family Fibronectin Filamin FLNA FN1 Follow-up Gene Expression Genes growth factor healthy controls healthy volunteer heat Heat shock heat shock protein hospital hospitalised hospitalized COVID-19 patient HSP90AA1 Human hypercoagulable in silico in silico prediction independent predictor independent predictors individual inflammatory reaction intensive care interquartile let-7b-5p Like member microRNA MicroRNAs miR-155 miR-16-5p miRNA miRNAs Multivariate analysis Myocardial nuclear pathway Pathways Patient patients hospitalized patients with COVID-19 performed peripheral Peripheral blood phosphatase play role polymerase chain positive Predictive prognostic biomarker Prognostic biomarkers Protein PTEN qRT-PCR Quantitative receptor Regulatory RNA SARS-CoV-2 selected Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Severity of infection silico prediction silico predictions Stratification tensin the healthy THROMBOPLASTIN thrombosis thrombotic Toll-like receptor TP53 UBC ubiquitin utility White blood cells
[DOI] 10.1080/15476286.2022.2100629 PMC 바로가기 [Article Type] Article

Glycosides for Peripheral Neuropathic Pain: A Potential Medicinal Components

Review

Published on 2021-12-312022-10-30
Journal: Molecules [Category] COVID-19,

Association of Peripheral Blood Parameters With Outcomes of COVID-19 Infection in a Tertiary Care Setting of Eastern India: An Institute-Based Study

Internal Medicine

Published on 2021-12-272022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] Absolute lymphocyte count absolute neutrophil count acute respiratory syndrome Admission AEC affected age ALC analyzed ANC association Blood blood sample caused Characteristics clinical symptom clinician Coagulation Comorbidity complete blood count conducted confirmed cases coronavirus COVID-19 D- dimer D-dimer death discharge disease Dyspnea eosinophil epidemiological Gender help hematological hypertension ICU ICU patient India inflammatory process information intensive care Liver disease Lymphocytes male-to-female ratio manifestation material Mortality Neutrophil-to-lymphocyte ratio Neutrophils NLR notable outcome outcomes pandemic parameter peripheral positive predict previous study progression reduce mortality Result risk RT-PCR SARS-CoV-2 setting shown statistical analysis study population Tertiary the disease
[DOI] 10.7759/cureus.20745 PMC 바로가기 [Article Type] Internal Medicine

The Role of Angiotensin Converting Enzyme 1 Insertion/Deletion Genetic Polymorphism in the Risk and Severity of COVID-19 Infection

Medicine

Published on 2021-12-232022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] ACE1 ACE1 ACE1 gene addition agarose gel age allele Analysis angiotensin association Blood carrier center clinical collected common allele Comorbidity Control COVID COVID-19 COVID-19 disease COVID-19 infection COVID-19 virus described determine disease disease severity DNA driving explain Factor Frequency Gender genetic differences Genetic polymorphism genetics Genotype genotyping greater Hospitalization I/D I/D polymorphism incidence increase in increased risk individual Infection Isolation management medical records outcome PCR PCR testing performed peripheral polymorphism positive predict Prognosis questionnaire recruited risk risk factor role severe symptom severity severity of COVID-19 Sex significantly higher significantly increased study population subjects susceptibility Symptom the disease university withdrawn
[DOI] 10.3389/fmed.2021.798571 PMC 바로가기 [Article Type] Medicine

Paralysie faciale périphérique post-vaccination COVID-19: à propos d’un cas

Case Report

Published on 2021-12-212022-10-28
Journal: The Pan African Medical Journal [Category] COVID-19, SARS,

[키워드] Anomaly cas clinique Case report COVID-19 COVID-19 vaccination COVID19 diagnostic facial palsy neuropathie Neuropathy observation périphérique Paralysie faciale Patient peripheral vaccination vaccination COVID-19
[DOI] 10.11604/pamj.2021.40.244.31498 PMC 바로가기 [Article Type] Case Report