Epidemiological surveillance of SARS-CoV-2 by genome quantification in wastewater applied to a city in the northeast of France: Comparison of ultrafiltration- and protein precipitation-based methods프랑스 북동부 도시에 적용된 폐수 게놈 정량을 통한 SARS-CoV-2의 역학 감시: 한외여과 및 단백질 침전 기반 방법의 비교Article Published on 2021-04-012022-09-11 Journal: International journal of hygiene and environmental [Category] SARS, 치료기술, [키워드] addition alcohol applied approach circulation clinical setting clinical settings collected Community Concentration Concentration methods COVID-19 COVID-19 case COVID-19 outbreak decrease develop Diagnosis eight epidemiological epidemiological surveillance evaluate evaluated France Genome human population inhibitors lockdown MONITOR Patient phage predict Prevalence processing Protein purification quantification required Respiratory samples RNA RNA extract RNA extracts RT-PCR SARS-CoV-2 SARS-CoV-2 genome Surveillance the SARS-CoV-2 genome Ultrafiltration undetectable university viral genome viral genomes Virological wastewater were used [DOI] 10.1016/j.ijheh.2021.113692 PMC 바로가기 [Article Type] Article
An in-vitro study on a novel six-phage cocktail against multi-drug resistant-ESBL Shigella in aquatic environmentarticle Published on 2021-03-312024-09-01 Journal: Letters in Applied Microbiology [Category] 세균성이질, [키워드] bacteriophage bio-control In-vitro phage phage cocktail Shigella water-borne [Article Type] article
Influence of Salmonella specific bacteriophages (O1; S16) on the shedding of naturally occurring Salmonella and an orally applied Salmonella Eastbourne strain in bearded dragons (Pogona vitticeps)Article Published on 2021-03-312024-09-07 Journal: Vet Med Sci [Category] 살모넬라증, [키워드] bearded dragon PCR phage reptile Salmonella PMC 바로가기
Learning From Mistakes: The Role of Phages in PandemicsMicrobiology Published on 2021-03-172022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] absence administration Antibiotic resistance Antibiotics Bacteria clinics develop emergent pathogen example global public health intensive care learning mandatory MDR multidrug-resistant Multidrug-resistant bacteria pandemic Patient phage phage therapy Prevent Prophylactic protocol public health reducing Regulation Research Respiratory Coronavirus role SARS-CoV-2 Secondary bacterial infections therapeutic approaches therapy Treatment treatment regimen [DOI] 10.3389/fmicb.2021.653107 PMC 바로가기 [Article Type] Microbiology
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interfaceSARS-CoV-2 중화 인간 재조합 항체는 RBD-ACE2 인터페이스에서 결합하는 팬데믹 전 건강한 기증자로부터 선택됩니다Article Published on 2021-03-112022-09-10 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료제, [키워드] ACE2 ACE2 receptor ACE2-RBD acute respiratory disease anti-SARS-CoV-2 antibody Antibody therapy binding Biotechnology candidate caused Cell cell entry coronavirus COVID-19 enzyme expressing Expression systems healthy healthy donor human ACE2 human donor IgG independent Infection Infectious diseases inhibit Interaction material naïve neutralization neutralize Neutralizing offer pandemic phage RBD RBD-ACE2 receptor Receptor binding domain recognizing recovering patient Respiratory disease S1 subunit sarbecovirus SARS-CoV-2 SARS-CoV-2 virus SARS-CoV-2 virus infection scFv selected Spike protein subsequent the S1 subunit the spike protein therapeutic unique VeroE6 cells Viral viral infection viral spike protein virus virus infection [DOI] 10.1038/s41467-021-21609-2 PMC 바로가기 [Article Type] Article
AMR and Covid-19 on the Frontline: A Call to Rethink War, WASH, and Public HealthViewpoint Published on 2021-02-242022-10-27 Journal: Annals of Global Health [Category] Coronavirus, MERS, [키워드] develop experience Factors greater hospital Mutation phage Public question Research surgeon Surveillance threat Transmission transmission route treated Treatment WASH zone [DOI] 10.5334/aogh.3140 PMC 바로가기 [Article Type] Viewpoint
Neutralizing Human Antibodies against Severe Acute Respiratory Syndrome Coronavirus 2 Isolated from a Human Synthetic Fab Phage Display Library인간 합성 Fab 파지 디스플레이 라이브러리에서 분리된 중증 급성 호흡기 증후군 코로나바이러스 2에 대한 인간 항체 중화Article Published on 2021-02-152022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, 진단, [키워드] absence ACE2 activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinities angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 anti-SARS-CoV-2 Antibody therapeutics apparent affinity avidity caused Cell coronavirus coronavirus 2 COVID-19 cross-reactivity D12 develop diagnostics display domain drug target Effect Fab Fabs FIVE Human human monoclonal antibodies Human monoclonal antibody IgGs Immunoglobulin In vitro assay Interaction Isolated library mAb mAbs MERS MERS-CoV moderate monoclonal antibody neutralize neutralizing activities Neutralizing activity outbreak pandemic phage phage display Prophylactic RBD reagent receptor protein Receptor-binding domain reported Research respiratory resulting SARS-CoV spike protein SARS-CoV-2 SARS-CoV-2 spike protein severe acute respiratory syndrome Coronavirus significantly Spike protein Spread synthetic the RBD the SARS-CoV-2 therapeutic drug thermal stability treat unique Vaccine Viral viral entry virus Wuhan Wuhan, China yielding [DOI] 10.3390/ijms22041913 PMC 바로가기 [Article Type] Article
Phage infection and sub-lethal antibiotic exposure mediate Enterococcus faecalis type VII secretion system dependent inhibition of bystander bacteria파지 감염 및 준치사 항생제 노출은 Enterococcus faecalis type VII 분비 시스템 의존적 방관자 억제 억제를 매개합니다.Research Article Published on 2021-01-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogate activated addition Affect antagonism antibacterial activity antibiotic Antibiotics Bacteria Bacterial bacterial cell bacterial cells Bacterial infections bacterial pathogen bacteriophage bacteriophages bacterium bystander Cell cells clinically Concentration Consensus consequence Contact Deletion Disruption DNA damage DNA damaging dose Enterococcus Evidence evidence of expression facilitate Gene Expression gram growth highlight Host Immunity independent independent of induce Infection Interaction intrinsic killing membrane microbial Microbial communities multi-drug resistant multidrug resistant pathogen phage phages positive predicted respond restrict resulting secretion Serine Staphylococcus aureus Stress stress response Stressor susceptible therapeutic therapy These data threonine Transcription transcription factor Treatment Trigger triggering triggers upstream [DOI] 10.1371/journal.pgen.1009204 PMC 바로가기 [Article Type] Research Article
A human antibody of potent efficacy against SARS-CoV-2 in rhesus macaques showed strong blocking activity to B.1.351붉은 털 원숭이에서 SARS-CoV-2에 대한 강력한 효능의 인간 항체는 B.1.351에 대한 강력한 차단 활성을 나타냈습니다Article Published on 2021-01-012022-09-11 Journal: mAbs [Category] MERS, 변종, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody B.1.1.7 B.1.351 binding blocking activity broad-spectrum cause clinical trial Complete convalescent plasma coronavirus coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 COVID-19 pandemic D614G demonstrated disease Efficacy hACE2 host cell host cell receptor in vitro Infection interact Intervention JMB2002 lead neutralization Neutralizing Neutralizing antibodies neutralizing antibody phage phage-to-yeast Phase 1 Phase 1 clinical trial platform Prophylactic Protein RBD Receptor binding domain respiratory rhesus rhesus macaque rhesus macaque disease model. SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence sera Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 the RBD the SARS-CoV-2 therapeutic therapeutic efficacy Transmission Vaccine virus yeast [DOI] 10.1080/19420862.2021.1930636 PMC 바로가기 [Article Type] Article
Sepsis, Phages, and COVID-19Review Published on 2020-10-152022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Anti-viral Bacteremia Bacterial infection clinical trial COVID-19 example excessive inflammatory response help Immunity Local occur Patient phage Sepsis severe COVID-19 syndrome therapy Treatment [DOI] 10.3390/pathogens9100844 PMC 바로가기 [Article Type] Review