European collaborations on medicine and vaccine procurementPolicy & Practice Published on 2021-10-012022-10-27 Journal: Bulletin of the World Health Organization [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] access activity challenge coronavirus disease country COVAX COVID-19 COVID-19 vaccine distribution effort Europe European European country Forum Health health-care system IMPROVE increasingly initiative involved joint knowledge mechanism mechanisms Medicine Medicines pandemic pharmaceutical Region risk Vaccine Vaccines Volume [DOI] 10.2471/BLT.21.285761 PMC 바로가기 [Article Type] Policy & Practice
The Particularities of Pharmaceutical Care in Improving Public Health Service during the COVID-19 PandemicReview Published on 2021-09-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] activities association associations Care China Community competent Complete Complication conducted coronavirus 2 counseling country COVID-19 COVID-19 pandemic COVID-19 pathology COVID-19 patients COVID-19 test deaths disease drug extension facilitate global healthcare Health health system healthcare healthcare services hospital identify implementation Improving information management measure pandemic pathology Patient Patient care performed pharmaceutical Pharmaceutical care pharmaceutical practice pharmaceutical services Pharmacist Pharmacy produced professionals provided Public public health quarantine Regulation respiratory SARS-CoV-2 service Support Treatment Vaccines [DOI] 10.3390/ijerph18189776 PMC 바로가기 [Article Type] Review
How the Global COVID-19 Pandemic Brought Drug and Vaccine Development into the Public Mainstream글로벌 COVID-19 팬데믹이 어떻게 약물 및 백신 개발을 대중의 주류로 끌어들였습니까?Review Published on 2021-09-012022-09-11 Journal: Pharmaceutical medicine [Category] 신약개발, [키워드] approved Clinical studies COVID-19 development drug Drug development drugs Effect effective vaccine Effective vaccines Effects effort Evolution health system health systems implementation include individual Infection mainstream pandemic Patient pharmaceutical pharmacovigilance populations Prevent product Public Regulatory SARS-CoV-2 virus the SARS-CoV-2 virus treat Vaccine [DOI] 10.1007/s40290-021-00402-y PMC 바로가기 [Article Type] Review
COVID-19: The Disease, the Immunological Challenges, the Treatment with Pharmaceuticals and Low-Dose Ionizing RadiationCOVID-19: 질병, 면역학적 도전, 의약품 및 저선량 전리 방사선 치료Review Published on 2021-08-272022-09-11 Journal: Cells [Category] MERS, SARS, 치료제, [키워드] alleviate Anti-inflammatory Antiviral applied cancer treatment clinical trial COVID-19 COVID-19 patients cytokine Cytokine storm death develop Dexamethasone digits disadvantage Disadvantages disease dosage Effect Effective strategies effective strategy empirical evidence Epidemiology Evidence globe health worker health workers immunological alterations life-threatening low-dose Low-dose radiotherapy motivation much lower mutations oxygen pandemic pharmaceutical Pneumonia Prevalence proliferation Radiation Registered Remdesivir SARS-CoV-2 severe COVID-19 patients Spread Symptom Symptoms the cytokine storm the disease therapeutic treating COVID-19 patients Treatment Vaccine development X-ray [DOI] 10.3390/cells10092212 PMC 바로가기 [Article Type] Review
“Waste Not, Want Not” — Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical MonitoringPreliminary Research Published on 2021-08-162022-10-30 Journal: Journal of Medical Toxicology [Category] Coronavirus, MERS, SARS, [키워드] aggregation analogue Analysis application Biomarker change COVID-19 disease COVID-19 pandemic develop disorder downstream drug drugs Epidemic Epidemiology fentanyl include manuscript medication metabolites MONITOR monitoring opioids Pathogens pharmaceutical plant powerful tool provide public health Research sewer Sewers Stimulants Surveillance System Treatment trend upstream Want wastewater [DOI] 10.1007/s13181-021-00853-4 PMC 바로가기 [Article Type] Preliminary Research
Can pharmaceutical drugs used to treat Covid-19 infection leads to human health risk? A hypothetical study to identify potential riskCovid-19 감염을 치료하는 데 사용되는 제약 약물이 인간 건강 위험으로 이어질 수 있습니까?잠재적 위험을 식별하기위한 가상의 연구Article Published on 2021-07-152022-08-31 Journal: The Science of the total environment [Category] SARS, 신약개발, 치료제, [키워드] acceptable daily intake activity adverse effect adverse effects affected Analysis approach aquatic environment assumption calculate Can carried Chloroquine Concentration Consumption contaminant contaminated surface COVID-19 COVID-19 infection COVID-19 pandemic determine drug drugs Effect estimate estimates evaluated expected Health hypothetical identify indicated Infection ingestion Lopinavir lopinavir + ritonavir maximum minimum mixture NOAEL novel Novel coronavirus pandemic PECs pharmaceutical Pharmaceuticals potential risk predicted Quotient Rapamycin RATs reduce Regular risk Risk estimation Ritonavir Rivers. Surface water Toxicity treat used to calculate water [DOI] 10.1016/j.scitotenv.2021.146303 PMC 바로가기 [Article Type] Article
Evaluation of the efficacy and safety of recombinant erythropoietin on the improvement of hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial입원한 COVID-19 환자의 개선에 대한 재조합 에리트로포이에틴의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-07-062022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 48 hours Adverse reaction Adverse reactions age approved Arm Bandar Abbas Blinding block randomization blood pressure Care checked chronic lung disease clinical clinical symptom clinical trial clinical trials Committee company comparator Patients composite endpoint control group Controlled clinical trial controls Coronary heart disease COVID-19 COVID-19 patient COVID-19 patients CRP Deep vein Deep vein thrombosis diabetes Diabetes Mellitus Diastolic blood pressure dissemination distilled water Efficacy and safety element End-stage renal disease endogenous enoxaparin erythropoietin ethics committee evaluate evaluate the effect excluded exclusion criteria expected Haemoglobin Health Health care heart disease hospitalised hospitalised COVID-19 patients Hypoxemia immune system infiltration injection intervals Intervention intervention group investigator Iran Laboratory test Laboratory tests LDH Liver disease Local Lung disease lung field lung infiltration lymphocyte Lymphocyte count lymphopenia Medical Science Medical Sciences medication minute number objective oral contraceptive outcome oxygen oxygen partial pressure oxygen saturation parallel-group partial pressure participant Patient PCR performed pharmaceutical Pharmaceutical Company Phase 2 Placebo positive Prevent principal investigator protocol randomised randomised controlled trial Randomized Randomly receive recombinant erythropoietin recruitment Registered registry renal disease reported respiratory respiratory rate Sample size saturation severe COVID-19 symptom severe COVID-19 symptoms Side effect Side effects Standard Standard of care status sterile water Study protocol subcutaneous injection subject supplementary material Systolic blood pressure tachypnea technology the ethics committee thrombosis title Treatment protocol treatment protocols Trial registration university vital signs water water for injection weakened immune system website [DOI] 10.1186/s13063-021-05363-w PMC 바로가기 [Article Type] Letter
Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2헤스페리딘에 의해 매개되는 항바이러스성 산화아연 나노입자와 항-SARS-CoV-2로서의 항바이러스성 페놀계 물질 간의 in silico 비교 연구Article Published on 2021-07-012022-09-11 Journal: Colloids and surfaces. B, Biointerfaces [Category] SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Analysis anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity Antiviral antiviral activity antiviral agent Antiviral agents assist caused characterized complementary Compound coronavirus COVID-19 curative death docking score evaluated example HAV Hepatitis hepatitis A hepatitis A virus hesperidin highest in silico Infection Isolation leads measure metabolite molecular docking nutraceutical nutraceuticals pandemic pharmaceutical Potential treatment predicted protocol protocols reducing reducing agent required respiratory responsible RNA viruses Safe SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Side effects synthesis TEM tested Treatment virus Zinc zinc oxide zinc oxide nanoparticles [DOI] 10.1016/j.colsurfb.2021.111724 PMC 바로가기 [Article Type] Article
Histopathological changes in Oreochromis mossambicus (Peters, 1852) ovaries after a chronic exposure to a mixture of the HIV drug nevirapine and the antibiotics sulfamethoxazole and trimethoprimHIV 약물 네비 라핀의 혼합물 및 항생제 설파 메톡 사졸 및 트리 메토 프림의 혼합물에 만성 노출 된 후 오레오 크로 미스 Mossambicus (Peters, 1852) 난소의 조직 병리학 적 변화Article Published on 2021-07-012022-08-31 Journal: Chemosphere [Category] MERS, SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition adverse effect adverse effects African AIDS antibiotic Antibiotics antiretroviral Antiretrovirals Antiviral aquatic environment ARV atresia Bacterial Biomarkers changes in Compound consequence continent coronavirus drug drugs Effect Endpoint epidemic diseases female fish Fish gonads histopathological Histopathology HIV HIV antiretrovirals HIV drug HIV/AIDS Human immunodeficiency virus immunodeficiency immunodeficiency virus incidence Infection Infectious disease Infectious diseases information interstitial tissue investigated nevirapine Oocyte outbreak pandemic pharmaceutical Pharmaceutical mixtures. recorded respiratory significant difference significant differences sulfamethoxazole Surface waters syndrome triggered trimethoprim Tuberculosis vacuolation Viral water [DOI] 10.1016/j.chemosphere.2021.129900 PMC 바로가기 [Article Type] Article
Different selection dynamics of S and RdRp between SARS-CoV-2 genomes with and without the dominant mutations우성 돌연변이가 있거나 없는 SARS-CoV-2 게놈 간의 S 및 RdRp의 다른 선택 역학Article Published on 2021-07-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, [키워드] affected appearance Betacoronavirus cells coding region content correlated COVID-19 COVID-19 pandemic Critical dominant fitness genomic Genotype genotypes glycoprotein highest infectiousness isolate isolates mutant Mutation mutation rate Mutation rates mutations pandemic peptide pharmaceutical Positive selection Protein RdRP Replication Research responsible RNA RNA polymerase RNA-dependent RNA polymerase S gene S protein SARS-CoV-2 SARS-CoV-2 genes SARS-CoV-2 genome SARS-COV-2 infection sequence shown surface Surface glycoprotein the S protein the SARS-CoV-2 genome Tolerance viral entry viral genome virus [DOI] 10.1016/j.meegid.2021.104796 PMC 바로가기 [Article Type] Article