platelet activation – Page 4 – Communicable Diseases Research

COVID-19 and thrombosis: The role of hemodynamics

Review article

Published on 2022-04-012022-10-05
Journal: Thrombosis research [Category] COVID19(2023년), SARS, 진단,

Platelets, Bacterial Adhesins and the Pneumococcus

혈소판, 세균 부착 인자 및 폐렴구균

Article

Published on 2022-03-252024-08-24
Journal: Cells [Category] 폐렴구균 감염증,

[키워드] MSCRAMMs platelet activation platelet killing Pneumolysin pore formation Staphylococcus aureus Streptococcus pneumoniae surface proteins toxin.

Specialized interferon action in COVID-19

코로나19에 특화된 인터페론 작용

Article

Published on 2022-03-152022-09-11
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, 유전자 메커니즘, 진단,

[키워드] Activation Antiviral association C-reactive protein cell types circulating clinical marker clinical markers COVID-19 COVID-19 pathology CyTOF cytokine diagnostic disease severity Effect endothelial damage example Hospitalization hospitalized COVID-19 patients IFN IFN signaling IFNA2 IFNA6 IFNB1 IFNg IFNs Immune cell immune cell types immune cells immune marker Impact Implications interferon Kynurenine Kynurenine pathway lymphocyte lymphoid marker neutrophil pathology platelet activation poor prognosis Protective proteomics SARS-CoV-2 Seroconversion severe disease Signaling significant decrease subset the strongest therapeutic transcriptional response type I unique
[DOI] 10.1073/pnas.2116730119 PMC 바로가기 [Article Type] Article

Proteomic profiling reveals a distinctive molecular signature for critically ill COVID-19 patients compared with asthma and chronic obstructive pulmonary disease

Proteomic profiling은 천식 및 만성 폐쇄성 폐 질환과 비교하여 중환자 COVID-19 환자를 위한 독특한 분자 서명을 나타냅니다

Article

Published on 2022-03-012022-09-11
Journal: International Journal of Infectious Diseases [Category] SARS, 유전자 메커니즘,

[키워드] airway Airway mucus Analysis Anemia Asthma bronchoscopy cascades changes in chronic obstructive chronic obstructive pulmonary disease chronic obstructive pulmonary disease (COPD) Coagulation complement Control controls COPD COTL1 COVID-19 COVID-19 case COVID-19 patient COVID-19 patients Critically ill Critically ill COVID-19 differentially expressed expression FGB FGG groups HBA1 HBB healthy controls IGLV3-19 iron Iron metabolism metabolism molecular molecular target mortality rate obstructive pulmonary disease outcome overlapping Pathways Patient performed platelet activation Protein Proteins proteomic Proteomic sequencing. provide PRTN3 pulmonary disease quantified Research Respiratory disease respiratory diseases reveal Sequencing severe COVID-19 sputum therapy
[DOI] 10.1016/j.ijid.2022.01.008 PMC 바로가기 [Article Type] Article

Immune-Mediated Platelet Activation in COVID-19 and Vaccine-Induced Immune Thrombotic Thrombocytopenia

Immunology

Published on 2022-02-222022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS,

Elevated Plasma Soluble C-Type Lectin-like Receptor 2 Is Associated with the Worsening of Coronavirus Disease 2019

Article

Published on 2022-02-142022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

Upregulation of cytokine signalling in platelets increases risk of thrombophilia in severe COVID-19 patients

Article

Published on 2022-02-112023-06-16
Journal: Blood cells, molecules & diseases [Category] COVID19(2023년), MERS, SARS,

[키워드] ARDS, acute respiratory disorder symptom Coagulation COVID-19 COVID-19, Coronavirus disease 2019 IL-6 platelet activation Platelet transcriptome SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 Thrombophilia TNFα
[DOI] 10.1016/j.bcmd.2022.102653 PMC 바로가기 [Article Type] Article

Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis

Research

Published on 2022-02-092022-11-01
Journal: Cell & Bioscience [Category] COVID-19,

[키워드] acute respiratory syndrome affected aggregation Analysis binding Cell circulating platelet Clinical outcome Coagulopathy coding coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression Critical eight energy metabolism feature healthy donors Hemostasis immune response immunothrombosis implication increased mortality Interaction involved mechanism molecular mechanism multiple organ failure Pathways patients with COVID-19 performed Platelet platelet activation Platelets promoted Protein provided regulate Result reveal risk RNA RNA Polymerase II RNA sequencing SARS-CoV-2 SARS-COV-2 infection severe COVID-19 disease severity significantly subunit supplementary material therapeutic strategy thrombosis thrombotic complication thrombus formation transcription factor transcriptional Transcriptome upstream with COVID-19
[DOI] 10.1186/s13578-022-00750-5 PMC 바로가기 [Article Type] Research

Montelukast Inhibits Platelet Activation Induced by Plasma From COVID-19 Patients

Pharmacology

Published on 2022-02-082022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] acute respiratory distress addition Affect aggregates antagonists anti-inflammatory properties arachidonic acid Asthma auxiliary Bronchoalveolar lavage cardiovascular diseases characteristic characterized circulating COVID-19 COVID-19 patient COVID-19 patients disease Efficacy elevated endothelial cell damage expression feature implicated induced Inflammation inhibit inhibiting involved leukotriene leukotriene antagonists leukotrienes lipid mediator LTC metabolism Microvesicles Montelukast P-selectin plasma platelet activation pro-inflammatory protective role receptor reducing resulting severe COVID-19 patient suggested syndrome thrombotic tissue Tissue Factor treatment for COVID-19 widespread
[DOI] 10.3389/fphar.2022.784214 PMC 바로가기 [Article Type] Pharmacology

Emerging Role of Platelet-Endothelium Interactions in the Pathogenesis of Severe SARS-CoV-2 Infection-Associated Myocardial Injury

중증 SARS-CoV-2 감염 관련 심근 손상의 발병에서 혈소판-내피 상호작용의 새로운 역할

Review

Published on 2022-02-042022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 치료법,

[키워드] Abnormalities ACE2 ACE2 receptor activated Activation activation of platelets Acute cardiac injury acute infection acute myocardial injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition angiotensin angiotensin-converting enzyme 2 arrhythmia calcium calcium-binding proteins cardiac complication Cardiac complications cardiac disorders cardiac injury cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease cardiovascular dysfunction Clinical course Clinical outcome Coagulation contribute corona virus disease (COVID-19) coronavirus defined described disease disease pathogenesis driven by dysfunction endothelial Endotheliitis event fatal complication hypercoagulability include Infection Inflammation Interaction mechanism morbidity and mortality MOST Myocardial myocardial injury nucleocapsid nucleocapsid (N) protein occur oxygen pandemic Patient Platelet platelet activation Platelets potential mechanism potential mechanisms Prevalence Proteins respiratory risk factor Risk factors role SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 virus Sepsis severe acute respiratory syndrome Coronavirus severe disease significantly Spike protein systemic inflammation the SARS-CoV-2 virus triggering turn Vascular endothelium Viral viral spike protein virus
[DOI] 10.3389/fimmu.2022.776861 PMC 바로가기 [Article Type] Review