Chemical Profile, Antioxidant Properties and Antimicrobial Activities of Malaysian Heterotrigona itama Bee Bread말레이시아 헤테로트리곤아 이타마 벌빵의 화학적 프로필, 항산화 특성 및 항미생물 활성이미지Article Published on 2021-08-152024-07-30 Journal: Molecules [Category] 세균성이질, [키워드] Heterotrigona itama bee bread microbial activities polyphenols [DOI] 10.3390/molecules26164943 PMC 바로가기 [Article Type] Article
Polyphenols Could Prevent SARS-CoV-2 Infection by Modulating the Expression of miRNAs in the Host CellsPerspectives Published on 2021-08-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] alveolar Analysis Antiviral antiviral properties antiviral property Apoptosis Cell cellular cellular miRNA Complication COVID-19 CoVs cytoplasm cytosol Defense degrade Endothelial cell endothelial cells expression Host host cell host miRNAs Hypothesis identify involved lung microRNA miRNA miRNAs modulate modulated modulating nutriepigenomic performed polyphenol polyphenols Prevent prevention Regulation RNA SARS-CoV-2 SARS-CoV-2 RNA single-stranded RNA virus target gene translation type 2 pneumocyte viral infection Viral proteins viral replication Viral RNA virus [DOI] 10.14336/AD.2021.0223 PMC 바로가기 [Article Type] Perspectives
Perspective: Nutritional Strategies Targeting the Gut Microbiome to Mitigate COVID-19 OutcomesArticle Published on 2021-07-302023-07-01 Journal: Advances in Nutrition [Category] SARS, [키워드] COVID-19 gut microbiota nutrition obesity omega-3 polyphenols Probiotics Vitamin D [DOI] 10.1093/advances/nmab031 PMC 바로가기
Potent phytochemicals against COVID-19 infection from phyto-materials used as antivirals in complementary medicines: a reviewReview Published on 2021-06-022022-10-31 Journal: Future Journal of Pharmaceutical Sciences [Category] COVID-19, [키워드] addition Analysis Antiviral authors Ayurveda and Siddha complementary COVID 19 COVID-19 infection COVID-19 pandemic COVID-19 situation Evidence free fatty acid help in silico In silico method Inclusion increase in Indian system of medicine main protease MDs Medicines outbreak outcome performed polyphenols potent produced Regulation Research researcher SARS CoV-2 selected Spike protein Traditional Chinese medicine treat [DOI] 10.1186/s43094-021-00259-7 PMC 바로가기 [Article Type] Review
Polyphenols are potential nutritional adjuvants for targeting COVID-19Review Published on 2021-06-012023-07-13 Journal: Phytotherapy research : PTR [Category] SARS, [키워드] COVID-19 Inflammation oxidative stress polyphenols respiratory virus SARS-CoV-2 [DOI] 10.1002/ptr.6992 [Article Type] Review
Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor ( in vitro ): A Promising Source of Novel Antiviral DrugsChemistry Published on 2021-04-282022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] 3CL ACE2 acute respiratory syndrome antiviral activities approaches caused compounds coronavirus disease Coronavirus-2 COVID-19 drug effective Efficacy Extract glycoprotein host cell Human human Angiotensin-converting enzyme in vitro in vivo inhibiting Interaction investigated involved new virus novel pandemic pathophysiology Peel plant polyphenols Pomegranate pomegranate (Punica granatum L.) peel extracts pomegranate peels PPE protease receptor Replication SARS-CoV-2 SARS-COV-2 infection Secondary Metabolite Source spike Spread the disease the SARS-CoV-2 therapeutic agents therapy Treatment Viral proteins virus virus entry [DOI] 10.3389/fchem.2021.638187 PMC 바로가기 [Article Type] Chemistry
Plant-Derived Food Grade Substances (PDFGS) Active Against Respiratory Viruses: A Systematic Review of Non-clinical StudiesNutrition Published on 2021-02-092022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] active against activity Against alteration antiviral agent article cell entry cell line cellular damage cellular homeostasis coronavirus cytotoxicity database dysregulation Effect effective Evidence examined fatty food Functional foods functions glycoside Glycosides glycyrrhizin GRADE HCoV HCoV-NL63 herbal tea host cells Human human parainfluenza virus human population human respiratory tract IAV IBV identify in vitro include inclusion criteria infect influenza A virus influenza B inhibit initial investigated Major Mouse models NL63 pathogenic viruses pathway plant polyphenols Prevalence Prevent proliferation reduce reduction Replication reported respiratory Respiratory Tract Infection (RTI) respiratory viral infection respiratory virus Respiratory virus infections reveal review rhinovirus RSV searched selected severity Stage substance survival Viral lifecyle viral pathogenesis viral-induced virus virus titer [DOI] 10.3389/fnut.2021.606782 PMC 바로가기 [Article Type] Nutrition
The Impact of Polyphenols-Based Diet on the Inflammatory Profile in COVID-19 Elderly and Obese PatientsPhysiology Published on 2021-01-122022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] ACE2 acting acute respiratory distress acute respiratory syndrome ARDS CD26 characterized Clinical deterioration clinical implication Cluster comorbid disorder coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient Cytokine storm develop diet disease elderly enzyme Evidence expression high-risk population Impact individual Inflammation inflammatory disorder inflammatory status kill knowledge marker morbidity and mortality obese COVID-19 patient pandemic Pathogenesis pathology polyphenols Prevent profile promote protective effect Respiratory failure resulting SARS-CoV-2 illness SARS-COV-2 infection senescence severe COVID-19 severity syndrome therapy viral-induced virus receptor World Health Organization [DOI] 10.3389/fphys.2020.612268 PMC 바로가기 [Article Type] Physiology
Can Natural Polyphenols Help in Reducing Cytokine Storm in COVID-19 Patients?천연 폴리페놀이 COVID-19 환자의 사이토카인 폭풍을 줄이는 데 도움이 될 수 있습니까?Review Published on 2020-12-122022-09-10 Journal: Molecules [Category] MERS, SARS, 치료제, [키워드] adjuvant adjuvants alteration Anti-inflammatory anti-inflammatory compound Anti-inflammatory drugs anti-inflammatory therapies Anti-inflammatory therapy antioxidant blocking agent blocking agents Can China chronic disease Chronic diseases classical Clinical practice clinical trials Compound contributing to COVID COVID-19 CRS cytokine Cytokine release syndrome Cytokines effective Effectiveness help immune system Infection Inflammation Inflammatory cytokine Inflammatory cytokines manuscript natural pathway patients with COVID-19 polyphenol polyphenols poor prognosis Prophylactic reducing reduction SARS-CoV-2 SARS-COV-2 infection severity Spread storm systemic inflammatory response Treatment [DOI] 10.3390/molecules25245888 PMC 바로가기 [Article Type] Review
Geranii Herba as a Potential Inhibitor of SARS-CoV-2 Main 3CL pro , Spike RBD, and Regulation of Unfolded Protein Response: An In Silico ApproachArticle Published on 2020-12-032022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] 3CL pro 3CLpro ACE2 receptor binding binding interaction Cell cell entry Compound coronavirus disease COVID-19 develop Diseases docking domain drug drug candidate Efficiency ellagic acid Endoplasmic reticulum Geranii Herba GRP78 help in silico Approach Infection inhibit inhibit SARS-CoV-2 Interaction kaempferol molecular molecular docking analysis Patient polyphenols polyprotein Potential Protein proteolytic quercetin RBD regulate remained replicase SARS-CoV-2 SARS-COV-2 infection Signaling Simulation study spike Stress Support surface receptor Symptom target proteins the SARS-CoV-2 the SARS-CoV-2 virus these compound unfolded protein response Vaccine viral infections [DOI] 10.3390/antibiotics9120863 PMC 바로가기 [Article Type] Article