The Effect of Pooling on the Detection of the Nucleocapsid Protein of SARS-CoV-2 with Rapid Antigen TestsArticle Published on 2021-07-192022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] 3D printing Antigen control line costly Course COVID COVID-19 pandemic detect detection Dilution Effect extraction buffer False positives Image analysis Laboratory Lateral flow test nucleocapsid protein operator participant Patient PCR-confirmed performed point-of-care pooling positive control produced R 2 Rapid rapid antigene test risk of infection SARS-CoV-2 SARS-COV-2 infection Schools sensitivity specimens Stress Swab swabs Test test line Viral antigen was obtained [DOI] 10.3390/diagnostics11071290 PMC 바로가기 [Article Type] Article
Environmental sampling for SARS-CoV-2 at a reference laboratory and provincial hospital in central Viet Nam, 2020Covid-19 Published on 2021-07-122022-10-28 Journal: Western Pacific Surveillance and Response Journal [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Admitted Patient biosafety collected conducted Contact Contamination contributed coronavirus Course COVID-19 COVID-19 cases determine hospital Hospital stay include Infection prevention Laboratory measure Measures novel coronavirus disease objective occurred Other Patient polymerase chain positive control Regular respiratory specimen responsible Result reverse transcription RT–PCR SARS-CoV-2 specimen Swab swabs tested Throat transported virus virus load [DOI] 10.5365/wpsar.2020.11.4.002 PMC 바로가기 [Article Type] Covid-19
Nationwide Seroprevalence of SARS-CoV-2 in Saudi Arabia사우디 아라비아에서 SARS-CoV-2의 전국적인 유행성Article Published on 2021-07-012022-09-12 Journal: Journal of infection and public health [Category] MERS, SARS, 진단, [키워드] addition antibody Asymptomatic Biochemistry caused co-morbidity collected COVID-19 COVID-19 cases COVID-19 infection COVID-19 pandemic COVID-19 patients Critical demographics determine estimate Estimated estimates Evidence groups Hail HCW HCWs healthcare worker healthy blood donor healthy blood donors hypertension in-house ELISA indicate Infection Jeddah Kingdom lab Mild National Non-COVID-19 pandemic Patient positive control Prevalence prevalence of COVID-19 reactive Region regions reported respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 seroprevalence Saudi Arabia sera serological Seroprevalence serum sample serum samples statistical subset virus spread [DOI] 10.1016/j.jiph.2021.04.006 PMC 바로가기 [Article Type] Article
Proteomic analysis of chicken bone marrow-derived dendritic cells in response to an inactivated IBV + NDV poultry vaccineArticle Published on 2021-06-162022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] Activation Analysis Biomarker Cell dendritic cell differentially expressed domains eight facilitated Gene regulation in immune cells homology immune responses in vivo inactivated Inactivated vaccine increased expression Infectious Bronchitis Virus Innate immune cells lipid metabolism lysed maturation mRNA mRNA expression mRNA translation newcastle disease virus PLIN2 positive control Potential biomarker Protein protein level Proteins proteomic Proteomic analysis provide PSMB1 significantly stimulated Stimulation subject the vaccine upregulated Vaccine vaccine-induced immune responses Vaccines were assessed [DOI] 10.1038/s41598-021-89810-3 PMC 바로가기 [Article Type] Article
In vitro activity of itraconazole against SARS‐CoV‐2Research Article Published on 2021-05-252022-10-04 Journal: Journal of medical virology [Category] SARS, 신약개발, 치료제, [키워드] 17‐OH itraconazole acute respiratory syndrome Animal coronaviruses Antiviral antiviral activity assays Belgian patient Caco‐2 cells carried Cell cells clinical benefit clinical study coronavirus coronavirus disease COVID‐19 demonstrated Efficacy effort EudraCT hospitalized COVID‐19 patient hospitalized COVID‐19 patients identify in vitro inhibited isolate itraconazole metabolite parent nucleoside Patient phenotypic positive control Prevent reduction reduction in Remdesivir reported SARS‐CoV‐2 SARS‐CoV‐2 shown vaccination Validity VeroE6‐eGFP cells viral replication [DOI] 10.1002/jmv.26917 PMC 바로가기 [Article Type] Research Article
COVID-19 serological survey using micro blood samplingArticle Published on 2021-05-042022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] antibody automated Blood blood sample capillary blood carried Cohort Combination controls COVID-19 cross-reactivity Cryoelectron microscopy ELISA ELISA protocol Epidemiology excluded hospital Japan Local Major MERS patient occupational health populations positive control post infection presence of antibody SARS-CoV-2 Science serological survey Serological testing seropositive individual serum serum antibody technology university viral infection website [DOI] 10.1038/s41598-021-88850-z PMC 바로가기 [Article Type] Article
Biological Cloth Face Coverings—The Reduction of SARS-CoV-2 and Influenza (H1N1) Infectivity by Viruferrin™ TreatmentArticle Published on 2021-04-302022-10-30 Journal: Materials [Category] COVID-19, [키워드] acute respiratory syndrome Aerosols Anti-viral application Biological Contact coronavirus COVID-19 decrease demonstrated droplet evaluated face Face masks FIVE H1N1 Infectious virus Infectivity influenza A influenza A virus influenza A viruses influenza viruses offer pandemic Particle Personal protective equipment personal protective material positive control reduce reduction remained Saliva SARS-CoV-2 significant difference stability statistically significant tested Transmission transmission of SARS-CoV-2 treated unique unlikely virus [DOI] 10.3390/ma14092327 PMC 바로가기 [Article Type] Article
COVID-19 serology in nephrology healthcare workers신장 의료 종사자의 COVID-19 혈청학Clinical Trial Published on 2021-04-092022-09-10 Journal: Wiener Klinische Wochenschrift [Category] MERS, SARS, 임상, 진단, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 antibody Antibody test antibody tests assays Asymptomatic individuals baseline borderline broad spectrum Care chronic Chronic kidney disease coronavirus Coronavirus-2 COVID-19 COVID-19 patients crisis examined Follow-up analysis healthcare worker Healthcare workers IgG IgG and IgM IgG positivity IgM IgM antibodies Infection information kidney Kidney disease Mortality neutralizing capacity nucleocapsid nucleocapsid protein pandemic Patient positive positive control positive controls registration number respiratory Result SARS-CoV‑2 serology serology test Seroprevalence serum sample serum samples specificity spike glycoprotein study participant supplementary material threshold Trial Registration Number Virus Disease western blotting [DOI] 10.1007/s00508-021-01848-5 PMC 바로가기 [Article Type] Clinical Trial
Repurposing of Some Natural Product Isolates as SARS-COV-2 Main Protease Inhibitors via In Vitro Cell Free and Cell-Based Antiviral Assessments and Molecular Modeling ApproachesArticle Published on 2021-03-042022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acetoside active against addition Anti-SARS-CoV-2 Activity antiviral medicine apigenin-7-O-glucoside approach assessment carried Compound Concentration coronavirus Coronavirus infections COVID-19 enzyme explain Free identify in vitro increase in inhibitors of SARS-CoV-2 isolate ligands modeling moderate naringenin natural overcome pandemic patients worldwide pharmacophore positive control product protease repurposing SARS-CoV-2 SARS-CoV-2 Egyptian strain SARS-CoV-2 main protease selected sennoside sennoside B Spread tested the SARS-CoV-2 Viral protein Virtual screening Zinc [DOI] 10.3390/ph14030213 PMC 바로가기 [Article Type] Article
Virus-Like Particles as Positive Controls for COVID-19 RT-LAMP Diagnostic AssaysResearch article Published on 2021-03-012022-10-05 Journal: Biomacromolecules [Category] SARS, 진단, [키워드] acute respiratory syndrome assays bacteriophage Qβ clinical setting Consensus Control coronavirus COVID-19 COVID-19 patient encapsidation gold standard highlighting include internal and external Internal control isothermal isothermal amplification lack molecular assays nucleocapsid overcome Particle plant virus plasmids polymerase chain positive control protocol Quantitative reagent Region reliability required reverse transcription RNA RNAs RNase P RT-LAMP RT-qPCR RT-qPCR assays SARS-CoV-2 shown stability target the SARS-CoV-2 Transcription virus Virus-like particle VLP VLPs [DOI] 10.1021/acs.biomac.0c01727 [Article Type] Research article