Surveillance of SARS-CoV-2 antibodies of patients in the local affected area during Wuhan lockdownWuhan Lockdown 동안 국소 영향을받는 지역에서 환자의 SARS-COV-2 항체 감시Research Article Published on 2022-01-042022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, 치료법, [키워드] affected age All participants clinic Clinical sign Clinical signs Comorbidity convalescent patient Convalescent patients COVID-19 COVID-19 outbreak COVID-19 pandemic fragment of gold herd immunity highest Humoral immunity IgG IgM IgM and IgG Immunity indicated individual individuals information Local lockdown medical staff men natural reservoir no significant difference nucleic acid nucleocapsid outbreak Outpatient participant Patient positive rate positive rates Prevalence prevalence rate provide qualitative test Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgM SARS-CoV-2 infections sensitivity Seroprevalence Serosurveillance significant difference significantly higher specificity Spike protein syndrome the mean the SARS-CoV-2 Vaccination strategy Vaccine virus was measured were measured women Wuhan [DOI] 10.1186/s12879-021-07010-w PMC 바로가기 [Article Type] Research Article
Persistence of live virus in critically ill patients infected with SARS-COV-2: a prospective observational studySARS-COV-2에 감염된 중환자에서 살아있는 바이러스의 지속성: 전향적 관찰 연구Observational Study Published on 2022-01-042022-09-11 Journal: Critical Care [Category] SARS, 임상, 치료기술, [키워드] 95% CI AUC best Chain Reaction COVID-19 COVID-19 pneumonia Critically ill patient Culture cycle cycle threshold detect determine diagnosis of COVID-19 ICU admission ICU patient ICU Patients infection control infectiousness initial intensive care unit interquartile range lab lack Level 4 Live virus mechanical ventilation median nasopharyngeal nasopharyngeal sample Nasopharyngeal samples nasopharyngeal sampling non-infectious observational study Patient patients with COVID-19 PCR test performed polymerase chain polymerase chain reaction positive positive rate positive RT-PCR Positive test predict Prospective prospective observational study repeated Result reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR severity of illness specificity Test threshold Vero Cell Vero cells Viral viral culture Viral RNA were measured with COVID-19 [DOI] 10.1186/s13054-021-03884-z PMC 바로가기 [Article Type] Observational Study
Microscopic segmentation and classification of COVID-19 infection with ensemble convolutional neural network앙상블 컨볼루션 신경망을 사용한 COVID-19 감염의 현미경 세분화 및 분류Article Published on 2022-01-012022-09-11 Journal: Microscopy research and technique [Category] SARS, 치료기술, [키워드] Accuracy classification computer tomography Convolutional neural network COVID-19 COVID-19 diagnosis COVID-19 infection COVID19 data set deep learning Deeplabv3 denoise convolutional neural network (DnCNN) early stage evaluated factory Health Organization healthcare healthy hidden manifested Microscopic Morphological mortality rate patient data patients phase positive rate public health reported Research ResNet-18 RNA SAE selected sputum stack sparse autoencoder deep learning model (SSAE). Stage World Health Organization [DOI] 10.1002/jemt.23913 PMC 바로가기 [Article Type] Article
Computer-aided COVID-19 diagnosis and a comparison of deep learners using augmented CXRs컴퓨터 지원 COVID-19 진단 및 증강 CXR을 사용한 심층 학습기의 비교Article Published on 2022-01-012022-09-11 Journal: Journal of X-ray science and technology [Category] SARS, 치료기술, [키워드] Accuracy augmentation CAD caused characteristic chest X-rays Chest X-Rays (CXRs) classification CNN computer-aided diagnosis (CAD) contagious Convolution convolution neural network (CNN) coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 diagnosis CXR datasets death develop Diagnosis diagnosis of COVID-19 dry cough Early detection early diagnosis evaluated experiment False negative false-negative False-positive fatigue feature Fever Final help IMPROVE injection Long long short-term memory network (LSTM) manifested Medical imaging memory mortality rate network Neural positive rate producing Radiographic receiver operating characteristic Recurrent Recurrent Neural Network reduce respiratory tract infection ROC sensitivity Short-Term Memory specificity Symptom the disease TPR trained model variety [DOI] 10.3233/XST-211047 PMC 바로가기 [Article Type] Article
Inactivated SARS-CoV-2 vaccines elicit immunogenicity and T-cell responses in people living with HIV비활성화된 SARS-CoV-2 백신은 HIV에 감염된 사람들에게 면역원성과 T 세포 반응을 유발합니다Clinical Trial Published on 2022-01-012022-09-12 Journal: International immunopharmacology [Category] MERS, SARS, 임상, 진단, [키워드] Adenovirus Analysis antibody B cells booster dose caused CD4 CD45RO CD8 Community comparable COVID-19 cytokine determine dose Effect elicit ELISA Enumeration evaluated exhibited expression flow cytometry healthy donor HIV HIV-positive individual IFN-γ IL-2 inactivated individuals influences on Laboratory lymphocyte magnitude memory T cell Messenger RNA mRNA neutralization Neutralization antibody Neutralizing antibodies neutralizing antibody Pearson correlation Peripheral blood PLWH positive rate positive rates recruited required response SARS-2-S SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 vaccines. Spearman Spike protein staining T-cell Response Th1 Th17 Th17 response Th2 TNF-α Treg Vaccine Vaccines was used with HIV [DOI] 10.1016/j.intimp.2021.108383 PMC 바로가기 [Article Type] Clinical Trial
A Cross Sectional Sampling Reveals Novel Coronaviruses in Bat Populations of GeorgiaArticle Published on 2021-12-312022-10-28 Journal: Viruses [Category] COVID-19, [키워드] alphacoronavirus Amino acid anal swab Asia bat bats Betacoronavirus Co-infection Complete conducted coronavirus CoV CoV genera Critical cross-sectional eastern europe eight Epidemics Europe Genetic Georgia Limited novel nucleotide occurred Pandemics pathogen Phylogenetic phylogenetic inference Phylogeny Population populations positive positive rate Research RT-PCR assays Sample sampling sequenced sequencing method tested [DOI] 10.3390/v14010072 PMC 바로가기 [Article Type] Article
Seven-Month Analysis of Five SARS-CoV-2 Antibody Assay Results after ChAdOx1 nCoV-19 Vaccination: Significant Decrease in SARS-CoV-2 Antibody TiterArticle Published on 2021-12-302022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Abbott acute respiratory syndrome antibodies antibody Antibody titer assay assays ChAdOx1 nCoV-19 change Complete contribute coronavirus Efficacy FIVE Genscript healthcare IgG investigated median positive rate Result Roche SARS-CoV-2 SARS-CoV-2 antibody SD Biosensor serum sample Seven Siemen Significant significantly titer vaccination Vaccination strategies Vaccination strategy Vaccine Viral load [DOI] 10.3390/diagnostics12010085 PMC 바로가기 [Article Type] Article
Presence of Anti-MDA5 Antibody and Its Value for the Clinical Assessment in Patients With COVID-19: A Retrospective Cohort StudyCOVID-19 환자의 임상 평가를 위한 항MDA5 항체의 존재 및 가치: 후향적 코호트 연구Immunology Published on 2021-12-202022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] acute respiratory distress syndrome (ARDS) adverse outcome Analysis anti-melanoma differentiation-associated gene 5 (MDA5) antibody antibody assessment Autoimmune Blotting clinical conducted coronavirus disease correlated COVID-19 COVID-19 patient COVID-19 patients deaths demonstrated dermatomyositis elevated ELISA finding indicated Innate immunity Inpatient Laboratory features MDA5 non-severe patient outcome outcomes Patient positive positive patient positive rate Presence prevalent recruited severe COVID-19 patients severe disease Severe patient severity significantly similarity survival value was determined with COVID-19 [DOI] 10.3389/fimmu.2021.791348 PMC 바로가기 [Article Type] Immunology
Dynamic changes of IgM and IgG antibodies in asymptomatic patients as an effective way to detect SARS‐CoV‐2 infectionResearch Article Published on 2021-12-162022-10-30 Journal: Journal of Clinical Laboratory Analysis [Category] COVID-19, [키워드] antibodies antibody Antibody detection Asymptomatic Asymptomatic case asymptomatic infections asymptomatic patient Blood change chemiluminescence close contact collected colloidal gold Concentration control group COVID‐19 COVID‐19 patient COVID‐19 detect different time point dynamic effective Epidemic global pandemic IgG IgG level IgM IgM and IgG interval investigated Level Nasopharyngeal swab no significant difference nucleic acid observation positive rate quarantine remained Result SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 significant difference significantly higher tested the healthy venous was used [DOI] 10.1002/jcla.24080 PMC 바로가기 [Article Type] Research Article
Effectiveness and Safety of Traditional Chinese Medicine in Treating COVID-19: Clinical Evidence from ChinaCommentary Published on 2021-12-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] accumulated Capsule carried China Chinese clinical Clinical symptoms COVID-19 COVID-19 transmission Decoction determine duration of hospitalization Efficacy Evidence Government Immunity Infection measure Medicine mortality rate occurred outbreak overall mortality Patient physician positive rate preventing disease progression promote Quality of life RECIPE reduced reducing reported Safety severe COVID-19 Signs and symptoms TCM Traditional traditional Chinese medicine (TCM) treat treating treating COVID-19 Treatment Treatment outcome viral nucleic acid Western medicine (WM) [DOI] 10.14336/AD.2021.0906 PMC 바로가기 [Article Type] Commentary