Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics녹농균(Pseudomonas aeruginosa): 병인, 독성 인자, 항생제 내성, 숙주와의 상호 작용, 기술 발전 및 새로운 치료법Review Published on 2022-06-252022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 유전자 메커니즘, [키워드] addition Antibiotic resistance Antibiotics antimicrobial autophagy Bacterial Bacterial pathogenesis bioinformatics burn wounds Cancer caused Cell signaling cGAS chronic obstructive clinically COPD COVID-19 CRISPR CRISPR-Ca cystic fibrosis Defense develop disorder drug drug resistance Drug screening effective effort Factor Factors fibrosis gram Host host defense host immune responses host-pathogen interaction immune immune responses immunodeficiency IMPROVE infect Infection infections Inflammasome Interaction intractable invasive LPS mammalian cell mechanism metabolomics molecular Non-coding RNAs opportunistic pathogen outer membrane P. aeruginosa pathogen Pathogenesis Pathways Patient platform Pseudomona Pseudomonas aeruginosa rapid progress Regulation Research scRNA-seq secretion Severe infection signaling pathways Strains therapy traits treat use of antibiotics Ventilation Vesicle virulence widespread [DOI] 10.1038/s41392-022-01056-1 PMC 바로가기 [Article Type] Review
NAD(H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis Research Published on 2022-06-062022-10-05 Journal: Nature nanotechnology [Category] 바이오마커, [키워드] addition Apoptosis approach Bacteremia Cell cells cellular death demonstrated help homoeostasis immune immunomodulator Infection Inflammation key factor life-threatening maintain modulating multidrug-resistant multiorgan injury NAD+ NADH organ dysfunction outcome Pathogenesis prevented Pseudomonas aeruginosa pyroptosis reduced responsible Sepsis suppressed the United State therapeutic efficacy therapy translational Transport treat Vascular function vascular homeostasis [DOI] 10.1038/s41565-022-01137-w [Article Type] Research
Pulmonary bacterial infections in adult patients hospitalized for COVID-19 in standard wardsObservational Study Published on 2022-06-012022-10-05 Journal: Infectious diseases now [Category] COVID19(2023년), SARS, 임상, [키워드] antibiotic use Antigen Bacteria Bacterial Bacterial infection bacteriological Blood Bordetella pertussis Bronchoalveolar lavage Characteristics Clinical data Co-infection collected conducted coronavirus cough COVID-19 COVID-19 pandemic CT-scan cultures diagnosed Enterococcus Fever France hospital hospitalized patients Infection Klebsiella Laboratory Legionella management median medical records Modification Mycoplasma nasopharyngeal occurred Oxygen requirement Patient patients hospitalized PCR PCR test pneumococcal Pneumonia positive Pseudomonas aeruginosa pulmonary retrospective SARS-CoV-2 screened Secondary infection sputum sputum samples Staphylococcus aureus Streptococcus pneumoniae with COVID-19 [DOI] 10.1016/j.idnow.2021.12.001 PMC 바로가기 [Article Type] Observational Study
Reducing broad-spectrum antibiotic use in intensive care unit between first and second waves of COVID-19 did not adversely affect mortalityArticle Published on 2022-06-012023-07-08 Journal: The Journal of hospital infection [Category] COVID19(2023년), [키워드] Antimicrobial stewardship Bacteraemia Co-infection COVID-19 Pseudomonas aeruginosa [DOI] 10.1016/j.jhin.2022.03.007 PMC 바로가기
Antimicrobial effects of microwave plasma-activated water with skin protective effect for novel disinfectants in pandemic era Research Published on 2022-04-082022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] addition antimicrobial Bacillus cereus can be used Cell cells Concentration Effect effective Effects Escherichia coli evaluated exhibited Factor global pandemic identify implication investigated pandemic era performed plasma problems produced protective effect Pseudomonas aeruginosa public health reactive reactive nitrogen Salmonella Typhimurium SARS-CoV-2 skin Staphylococcus aureus Support Toxicity viability [DOI] 10.1038/s41598-022-10009-1 [Article Type] Research
Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections Research Published on 2022-03-092022-10-05 Journal: Nature Communications [Category] 변종, 진단, [키워드] Administered Amplicon sequencing analyzed antibiotic Antibiotic resistance Antibiotic therapy Bacterial infection bacterial respiratory infection changes changes in clinically collected Cycling driving early stage Effect Evolution Frequency genomic in vivo frequency Infection isolate mechanically ventilated patient Mutation Patient Population Pseudomonas aeruginosa Rapid resistance to antibiotics respiratory infection Sequencing Sputum sample Surveillance switching therapy treated Treatment [DOI] 10.1038/s41467-022-28188-w [Article Type] Research
Metagenomic Sequencing and Reverse Transcriptase PCR Reveal That Mobile Phones and Environmental Surfaces Are Reservoirs of Multidrug-Resistant Superbugs and SARS-CoV-2Metagenomic Sequencing 및 Reverse Transcriptase PCR, 휴대전화와 환경 표면이 다제내성 슈퍼버그 및 SARS-CoV-2의 저장소임을 밝혀내다Article Published on 2022-03-082022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 치료기술, [키워드] Acinetobacter aggregation Analysis antimicrobial resistance Aspergillus Bacterial bacteriophages Care carried Combination Community conducted Contamination COVID-19 COVID-19 patients Culture dissemination drug-resistant Emergency fomites fungi HCW HCWs healthcare worker Healthcare workers hospital Malassezia metagenomic metagenomic sequencing methicillin methicillin-resistant Staphylococcus aureus microbe microbes microbial Mobile mobile phone mobile phones molecular motility non-COVID-19 patient Non-COVID-19 patients P. aeruginosa pathogen pathogenic Patient PCR phenotypic point prevalence positive predominant preponderance Prevalence Pseudomonas Pseudomonas aeruginosa reservoir resistance gene risk RT-PCR SARS-CoV-2 SARS-CoV-2 detection Sequencing shotgun shotgun metagenomics. Staphylococcus Staphylococcus aureus Staphylococcus epidermidis surface Swab swabs transfer virulent zone [DOI] 10.3389/fcimb.2022.806077 PMC 바로가기 [Article Type] Article
Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021)Research Published on 2022-03-072022-10-28 Journal: Antimicrobial Resistance and Infection Control [Category] COVID-19, MERS, SARS, [키워드] 95% CI Acinetobacter Analysis antimicrobial antimicrobial resistance article Bacterial calculated Candida clinical settings co-infecting Co-infection conducted COVID-19 COVID-19 patient estimate etiologies Europe fungal heterogeneity hospital ICU identify IMPROVE inclusion criteria Infection prevention isolate Klebsiella pneumoniae Laboratory Meta-analysis Mortality multi-drug resistant objective organism Organisms pandemic Patient patient population patients hospitalized patients with COVID-19 performed Prevalence proportion Pseudomonas aeruginosa random effect ranged reported Research Result SARS-CoV-2 searched Staphylococcus aureus statistically significant supplementary material Surveillance systematic review unique Variation Web of Science were infected with COVID-19 [DOI] 10.1186/s13756-022-01085-z PMC 바로가기 [Article Type] Research
Sustainable Antibacterial and Antiviral High-Performance Copper-Coated Filter Produced via Ion Beam TreatmentArticle Published on 2022-03-022022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] acute respiratory syndrome Antibacterial Antiviral ATCC Bacteria beam Contact copper coronavirus disease Escherichia coli fiber Filter inactivated Ion ion beam Klebsiella pneumoniae lack microorganism occur oxygen Pseudomonas aeruginosa replaced risk SARS-CoV-2 SARS-CoV-2 virus secondary infections significantly more Spread Staphylococcus aureus temperature treat [DOI] 10.3390/polym14051007 PMC 바로가기 [Article Type] Article
Evaluation of bacterial agents isolated from endotracheal aspirate cultures of Covid-19 general intensive care patients and their antibiotic resistance profiles compared to pre-pandemic conditions코로나19 일반 중환자실 환자의 기관내 흡인 배양액에서 분리한 세균성 물질의 평가와 전염병 이전 상태와 비교한 항생제 내성 프로파일Article Published on 2022-03-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료기술, [키워드] Acinetobacter age amoxicillin Antibiotic resistance Antibiotics antimicrobial Antimicrobial stewardship Bacterial bacterial co-infection Candida cefepime Ceftazidime ciprofloxacin clavulanic acid clinical Clinical outcome colistin condition Course COVID-19 pandemic Critically ill Critically ill patient critically ill patients Culture cultures died ertapenem Escherichia coli evaluated Gender growth ICU imipenem increase increase in infected with SARS-CoV-2 intensive care intensive care follow-up intensive care patient intensive care unit Klebsiella pneumoniae levofloxacin meropenem microorganism more difficult Mortality no significant difference nosocomial Nosocomial pneumonia P. aeruginosa pandemic Patient patients hospitalized piperacillin piperacillin-tazobactam Pneumonia pneumoniae Prevalence prevalent profile Pseudomonas aeruginosa SARS-CoV-2 Secondary infection secondary infections shown significant difference Staphylococcus aureus statistically significant statistically significant difference strain Strains tazobactam the mean tigecycline tobramycin Treatment VAP Ventilator-associated pneumonia while [DOI] 10.1016/j.micpath.2022.105409 PMC 바로가기 [Article Type] Article