A novel deep learning-based quantification of serial chest computed tomography in Coronavirus Disease 2019 (COVID-19)코로나바이러스 질병 2019(COVID-19)에서 직렬 흉부 컴퓨터 단층 촬영의 새로운 딥 러닝 기반 정량화Article Published on 2021-01-112022-09-01 Journal: Scientific Reports [Category] 진단, [키워드] benefit calculated Chest computed tomography chest CT scan Chest CT scans Computed tomography Conventional correlation COVID-19 deep learning demonstrated disease severities disease severity estimation faster groups involved lesions moderate Patient performed predicted pulmonary involvement pulmonary lesion pulmonary lesions quantification reached semi-quantitative severe group Severe patient Spearman’s correlation symptom onset Translational research viral infection [DOI] 10.1038/s41598-020-80261-w PMC 바로가기 [Article Type] Article
Longitudinal clinical and radiographic evaluation reveals interleukin-6 as an indicator of persistent pulmonary injury in COVID-19종단 임상 및 방사선 사진 평가에서 코로나19의 지속적인 폐 손상의 지표로 인터루킨-6이 밝혀졌습니다.Research Paper Published on 2021-01-012022-09-10 Journal: International Journal of Medical Sciences [Category] MERS, 바이오마커, [키워드] Admission Analysis analyzed association B cell B cells CD19 CD4 CD8 change Chest computed tomography Chest CT Clinical management collected Computed tomography coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patients cross-sectional analysis disease course elevated evaluate expression favor feature Features follow-up period IL-6 immunological increase in independent interleukin interleukin-6 Intervention laboratory-confirmed lesion lesions longitudinal Lung injury lymphocyte Lymphocytes Mild moderate Multivariate analysis neutrophil Neutrophils outcome Patient patients Peripheral blood Peripheral blood sample peripheral blood samples Previous studies previous study Prolonged pulmonary injury pulmonary lesion pulmonary lesions Radiographic rationale reveal scored semi-quantification sequential monitoring Severe patient severe patients significantly sustained T cells the disease [DOI] 10.7150/ijms.49728 PMC 바로가기 [Article Type] Research Paper
Analysis of Chest CT Results of Coronavirus Disease 2019 (COVID-19) Patients at First Follow-Up2019년 코로나바이러스감염증-19(COVID-19) 환자의 1차 추시 시 흉부 CT 결과 분석Research Article Published on 2020-11-012022-09-12 Journal: Canadian Respiratory Journal [Category] MERS, SARS, 진단, [키워드] Admission analyzed Chest CT consolidation COVID-19 cured discharge exclusion criteria faster Follow-up ground-glass opacity hospital Inclusion lesion lesions Manifestations moderate objective outcome Patient patients with COVID-19 proportion pulmonary lesion pulmonary lesions radiologist remained required Result Severe case severe cases Severe patient severe patients statistically [DOI] 10.1155/2020/5328267 PMC 바로가기 [Article Type] Research Article
Application value of artificial liver support system in the treatment of cytokine storm in patients with COVID-19Article Published on 2020-10-312022-10-04 Journal: International immunopharmacology [Category] SARS, 치료법, [키워드] abnormality addition alanine aminotransferase ALT Analysis analyzed application Artificial liver support system Aspartate aminotransferase AST B lymphocyte C-reactive protein carried CD3 CD4 CD8 T cell Cell Clinical effect Clinical treatment college Computed tomography contributed coronavirus disease COVID-19 COVID-19 patients cytokine cytokine level Cytokine storm decrease IFN-γ IL-10 IL-2 IL-4 IL-6 Inflammation lesions liver lymphocyte Medicine natural killer neutrophil no significant difference objective observé Patient patients with COVID-19 plasma exchange procalcitonin promote proportion pulmonary lesion pulmonary lesions recruited reduce reduced Result severe COVID-19 patient significantly Support the patient TNF-α treated Treatment university was used White blood cell Zhejiang [DOI] 10.1016/j.intimp.2020.107120 PMC 바로가기 [Article Type] Article
Clinical characteristics and outcomes of discharged COVID-19 patients with reoccurrence of SARS-CoV-2 RNACase Series Published on 2020-10-222022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] 2019 coronavirus disease Characteristics Chest clinical Clinical characteristics close contact COVID-19 COVID-19 patient COVID-19 patients discharge discharged dry cough fatigue Fever hospital Infection initial Laboratory outcome outcomes Patient pharyngeal positive pulmonary lesion reoccurrence SARS-CoV-2 SARS-CoV-2 RNA significantly Symptoms Transmission worsening [DOI] 10.2217/fvl-2020-0142 PMC 바로가기 [Article Type] Case Series
Immunopathogenesis of SARS-CoV-2-induced pneumonia: lessons from influenza virus infectionReview Published on 2020-10-122022-10-30 Journal: Inflammation and Regeneration [Category] COVID-19, [키워드] Activation acute respiratory syndrome alveolar alveolar epithelial cell Asymptomatic Asymptomatic individuals cause CCL2 CD4 CD8 characteristic chemokines Coronavirus-2 Critical Cytokines Diffuse alveolar damage disease severity effector molecule Endothelial cell Factor foci Host IL-1β induce infect Infection inflammatory monocyte Influenza virus Injury interstitial inflammation involved life-threatening Ligand lung Macrophage memory Mild Necrosis neutrophil infiltration nitric oxide Pathogenesis pathology Pneumonia Prevent progression pulmonary lesion SARS-CoV-2 Signaling spread to systemic symptom T cell T cells T-cell Response T-cell responses tissue injury type I interferon upper respiratory tract vicious cycle viral spread virus clearance [DOI] 10.1186/s41232-020-00148-1 PMC 바로가기 [Article Type] Review
The efficacy assessment of convalescent plasma therapy for COVID-19 patients: a multi-center case seriesArticle Published on 2020-10-062022-10-04 Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 바이오마커, 치료제, [키워드] adverse event antibody C-reactive protein case sery change Chest CT Clinical efficacy Clinical symptoms Convalescent plasma therapy coronavirus disease correlated COVID-19 Critical Donor donors dose Efficacy eight enrolled evaluate Factor FIVE immunology Immunotherapy IMPROVE indicated Infectious diseases laboratory parameter Laboratory parameters Liver function lymphocyte counts neutralizing antibody oxygen support Patient plasma potential therapy procalcitonin pulmonary lesion Quality control radiological risk serology test Seven severe COVID-19 patient Severe patient therapy transfused Treatment Variation viral infections Viral load with COVID-19 [DOI] 10.1038/s41392-020-00329-x PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts아프리카 녹색 원숭이의 SARS-CoV-2 감염은 PET/CT 영상으로 식별할 수 있는 경증의 호흡기 질환을 일으키고 호흡기 및 위장관 모두에서 전염성 바이러스를 배출합니다Research Article Published on 2020-09-182022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, SARS, [키워드] aerosol African green monkey African green monkeys AGM animal model Asymptomatic can be used candidate vaccine combating Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cases COVID-19 disease Critical days post-infection decrease detectable disease Efficacy followed by Future gastrointestinal system gastrointestinal tract gastrointestinal tracts GI tract tissues green monkeys human clinical trials humans IgM and IgG imaging Infection Infectious virus lesion lesions Live virus lung lesion lung lesions lung tidal volume Lungs Mild Mild disease mild respiratory mucosal exposure necropsy NHP non-human primate pandemic Pathogenesis performed pet PET/CT positron emission Positron emission tomography provide pulmonary lesion pulmonary lesions recrudescence resolved respiratory RNA SARS-CoV-2 SARS-COV-2 infection seroconverted severe disease shedding species therapeutic interventions Tidal volume tissue viral load tomography Vaccine Viral Viral load Viral RNA virus Virus shedding vRNA [DOI] 10.1371/journal.ppat.1008903 PMC 바로가기 [Article Type] Research Article
Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case seriesResearch article Published on 2020-09-012022-10-05 Journal: Virology [Category] SARS, 치료법, [키워드] administration All the patient case sery clinical condition Clinical symptoms COVID-19 COVID-19 patient Deterioration diagnosed discharged dose Effect high mortality High-dose hospital IMPROVE improvement Intravenous immunoglobulin IVIG morbidity O2 Saturation Patient PCR populations Prevalence Prevent prevented progression pulmonary lesion receive reported severe symptom standard treatment the disease therapeutic therapeutic response treated Treatment [DOI] 10.1016/j.virol.2020.05.006 [Article Type] Research article
Clinical and imaging findings of discharged patients with SARS-CoV-2 positive anal swab samples: a descriptive studyResearch Article Published on 2020-09-012022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome anal swab Asymptomatic case Blood Case series caused Chest CT China clinical Clinical characteristics clinical feature clinically coronavirus coronavirus disease COVID-19 CT finding CT scan cured diarrhea discharge discharged patient discharged patients duration of fever Evolution feature Fever gastrointestinal symptoms groups incidence Laboratory male median no significant difference Patient patients patients with COVID-19 positive positive patient pulmonary lesion Result RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Stool Symptom tested the patient two groups Viral RNA [DOI] 10.1186/s12879-020-05363-2 PMC 바로가기 [Article Type] Research Article