Advanced Materials for SARS-CoV-2 VaccinesSARS-CoV-2 백신용 첨단 소재Review Published on 2022-03-012022-09-12 Journal: Advanced Materials (Deerfield Beach, Fla.) [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adjuvant advance Antibody Response approach caused Combination coronavirus disease COVID-19 COVID-19 vaccine COVID-19 vaccines dimension dosage induce material mitigate mRNA vaccine pandemic produced Respiratory Coronavirus SARS-CoV-2 spike Subunit vaccine unique Vaccine vaccine platform Vaccines [DOI] 10.1002/adma.202107781 PMC 바로가기 [Article Type] Review
Co-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong홍콩에서 수입된 애완용 햄스터 내에서 두 개의 SARS-CoV-2 변종 균주의 공동 순환Coronaviruses Published on 2022-02-272022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] adaptive animal animals aviation binding energy can not coronavirus COVID-19 Delta delta variant epidemiologically Europe European hamster hamsters Hong Kong Human human ACE2 interspecies molecular docking Netherland Netherlands outbreak Outbreaks Patient phylogenetically positive Prevent RBD reported respiratory Respiratory Coronavirus risk SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory coronavirus spike mutation spike receptor-binding domain spike variant spike variants strain Strains subsequent suggested susceptible Testing these viruses Transmission triggered variant virus viruses warehouse while zoonosis [DOI] 10.1080/22221751.2022.2040922 PMC 바로가기 [Article Type] Coronaviruses
Developing an Effective Peptide-Based Vaccine for COVID-19: Preliminary Studies in Mice ModelsCOVID-19에 대한 효과적인 펩티드 기반 백신 개발: 마우스 모델의 예비 연구Article Published on 2022-02-222022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] adjuvant affinity antibody Antibody Response autoimmune responses B cell epitope B cell epitopes B cell response C57BL/6 caused convalescent individuals coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated Developing effective Effectiveness epitope epitope mapping Epitopes flexibility generate Health HLA Human in silico mice Model Neutralizing Neutralizing activity peptide peptide-based vaccine peptides plasma predicted Prevent produced Protein Respiratory Coronavirus Safe SARS-CoV-2 SARS-CoV-2 variant selected Spike protein Spread stimulated T and B cell responses T and B cells T cell T cell responses tested two group two groups Vaccine viral variant Viral variants virus wild-type [DOI] 10.3390/v14030449 PMC 바로가기 [Article Type] Article
Seroprevalence of SARS-CoV-2 Among Workers in Northern Italy북부 이탈리아의 노동자들 사이에서 SARS-CoV-2의 혈청 유병률Article Published on 2022-02-182022-09-12 Journal: Annals of work exposures and health [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% confidence interval age calculated Chi square test Cluster collected conducted COVID-19 symptom cross-sectional evaluate evaluated Gender geographical location healthcare identify IgG Immunoglobulin Italy lockdown male pandemic Probability public health recorded Respiratory Coronavirus SARS-CoV-2 serological test Seroprevalence shown Spread statistical subject tested the SARS-CoV-2 Transmission variable worker Workers [DOI] 10.1093/annweh/wxab062 PMC 바로가기 [Article Type] Article
Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variantsSARS-CoV-2 감염 전후에 백신 접종은 강력한 체액 반응과 변이체를 효과적으로 중화시키는 항체로 이어집니다.Article Published on 2022-02-182022-09-11 Journal: Science Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] age antibody Antibody Response Antibody responses antigen exposure boost breadth Breakthrough infection breakthrough infections coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 current Effect groups humoral humoral immune response immune immune response immune responses Immunity individual Infection morbidity and mortality natural infection neutralize Neutralizing antibody response neutralizing antibody responses no correlation no infection occur pandemic quantity reduce respiratory Respiratory Coronavirus robust SARS-CoV-2 SARS-COV-2 infection sera vaccinated individuals vaccination Vaccine variant [DOI] 10.1126/sciimmunol.abn8014 PMC 바로가기 [Article Type] Article
Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lungDiltiazem은 SARS-CoV-2 세포 부착 및 내재화를 억제하고 마우스 폐의 바이러스 감염을 감소시킵니다Research Article Published on 2022-02-172022-09-10 Journal: PLoS Pathogens [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] ACE2 Affect affecting anti-SARS-CoV-2 antiviral drug antiviral drugs appear approved attachment Author binding blocker Breakthrough infection breakthrough infections calcium calcium channel Cell Clinical practice coronavirus COVID-19 COVID-19 treatment decrease Diltiazem drug drugs Effectiveness Emergency use FDA-approved drug highlight hospitalized COVID-19 patients indications inhibit interact internalization L-type lung occurred raise recipient recipients Remdesivir Research research and development respiratory Respiratory Coronavirus Safe SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines severe acute respiratory coronavirus Spike protein subunit Support the vaccine the vaccines treat Treatment US FDA variant variants variants of SARS-CoV-2 Viral viral entry viral infection [DOI] 10.1371/journal.ppat.1010343 PMC 바로가기 [Article Type] Research Article
A review on the induction of host immunity by the current COVID-19 vaccines and a brief non-pharmaceutical intervention to mitigate the pandemicReview Published on 2022-02-162022-10-28 Journal: Bulletin of the National Research Centre [Category] COVID-19, [키워드] Abstract antiviral drug approach approaches avoidance cellular COVID-19 pandemic COVID-19 severity COVID-19 situation COVID-19 vaccine effective Genetic global public health Health host immunity humoral immune response Intervention knowledge MERS-CoV Middle East mitigate Non-pharmaceutical interventions pandemic platform positive result present Protective Respiratory Coronavirus respiratory syndrome coronavirus SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 variants second wave similarity the SARS-CoV-2 vaccination Vaccine Vaccine development Vaccines variants variants of SARS-CoV-2 viral escape while [DOI] 10.1186/s42269-022-00719-x PMC 바로가기 [Article Type] Review
Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant CellsArticle Published on 2022-02-112022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), SARS, [키워드] accumulate Analysis anti-SARS-CoV-2 antimalarial antimalarial drug Antiviral approved drug assays Calu-3 Calu-3 cell Cell cell line Chloroquine clinical benefit clinical trials clinically concentrations COVID-19 differential expression example HCQ Human IL-6 in vitro in vitro activity information inhibit inhibited Interaction investigated lack Lungs mechanism of action mefloquine modulated monocyte Monocytes optimal dose parameter pathway pharmacological plasma predicted prevented reduced Respiratory Coronavirus respiratory diseases SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 replication SARS-CoV-2 RNA solidarity therapeutic therapy TMPRSS2-expressing cells TNF-α type II pneumocytes virus entry were assessed [DOI] 10.3390/v14020374 PMC 바로가기 [Article Type] Article
SARS‐CoV‐2 Omicron variant: A next phase of the COVID‐19 pandemic and a call to arms for system sciences and precision medicinePerspective Published on 2022-02-112022-10-30 Journal: MedComm [Category] COVID-19, [키워드] 3D models Arm artificial B.1.1.529 continuous variation coronavirus disease correlated COVID‐19 COVID‐19 infection Defense delta variant diagnose diagnostics Efficiency exhibited Health health systems high mortality Hospitalization in vitro Infection intelligence introduced mechanism mutated Mutation mutations nanomedicine natural immunity omicron pandemic Pathogenesis Perspective Precision precision medicine provided receptor‐binding domain recommendation reservoirs Respiratory Coronavirus SARS‐CoV‐2 SARS‐CoV‐2 mutations severity Spread Structure subtype System the spike protein Vaccines variant variants viral infection virus VOCs World Health Organization [DOI] 10.1002/mco2.119 PMC 바로가기 [Article Type] Perspective
Serologic Survey of IgG Against SARS-CoV-2 Among Hospital Visitors Without a History of SARS-CoV-2 Infection in Tokyo, 2020–2021도쿄에서 SARS-CoV-2 감염 이력이 없는 병원 방문자 중 SARS-CoV-2에 대한 IgG의 혈청학적 조사, 2020-2021Original Article Published on 2022-02-052022-09-12 Journal: Journal of Epidemiology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI 95% confidence interval Against age All participants anti–SARS-CoV-2 IgG antibody blood collection Capital chemiluminescence immunoassay China confirmed cases coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related symptom COVID-19-related symptoms cross-sectional cross-sectional study diagnosed ENhance Epidemic exhibited high risk history hospital hospital visitors iFlash IgG IgG seroprevalence individual Infection Japan participant Patient positive result Randomly Respiratory Coronavirus Result SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection selected serologic seropositive Seroprevalence serum serum sample serum samples Sex Shenzhen Shenzhen YHLO Biotech survey the SARS-CoV-2 Tokyo Visitor was tested [DOI] 10.2188/jea.JE20210324 PMC 바로가기 [Article Type] Original Article