severe cases – Page 4 – Communicable Diseases Research

Coagulation Abnormalities and Management in Hospitalized Pediatric Patients With COVID-19

COVID-19로 입원한 소아 환자의 응고 이상 및 관리

Article

Published on 2022-07-012022-09-11
Journal: The Pediatric Infectious Disease Journal [Category] COVID19(2023년), SARS, 치료기술,

Features of antibody responses after SARS-COV-2 infection in healthcare workers in the first wave of COVID-19 pandemic in Mexico City

멕시코시티 COVID-19 전염병의 첫 번째 물결에서 의료 종사자의 SARS-COV-2 감염 후 항체 반응의 특징

Article

Published on 2022-07-012022-09-11
Journal: The Journal of international medical research [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] age Analysis Antibody Response Antibody responses Antibody titre COVID COVID-19 COVID-19 pandemic cross-sectional cross-sectional study elicited Factor First wave HCW HCWs healthcare healthcare worker Healthcare workers hospital identify IgG IgG antibodies IgG antibody IgM Immunoglobulin inch Infection intensity involved Isolation lateral flow mandatory measure men men and women Mexico City no differences old age Participants produced recovering from COVID-19 risk of infection SARS-CoV-2 SARS-COV-2 infection semiquantitatively Seroprevalence severe cases significantly higher spread of COVID-19 Symptom the antibody response virus women
[DOI] 10.1177/03000605221099458 PMC 바로가기 [Article Type] Article

Immune features of COVID-19 convalescent individuals revealed by a single-cell RNA sequencing

단일 세포 RNA 시퀀싱으로 밝혀진 COVID-19 회복기 개인의 면역 기능

Article

Published on 2022-07-012022-09-11
Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

[키워드] Activation addition B cell B cell subset B cells Bioinformatics analysis biological processe biological processes CD4 CD8 Cell cell receptor cell-cell adhesion clonal expansions Cluster convalescence convalescent convalescent COVID-19 patient convalescent COVID-19 patients convalescent individual convalescent individuals convalescent patient Convalescent patients COVID-19 Critical declined decreased expression differentiation downregulation effector memory feature function functions GNLY HLA class I HLA class II HLA class II genes humoral immune response Humoral immunity immune protection immune response immune responses increased expression infections Innate innate immune responses Innate immunity Interferon-gamma involved leukocyte mapped marginal zone mechanism Migration moderate natural infection neutrophil Peripheral blood peripheral blood samples phenotypic reflected Regulation Reinfection retained RNA SARS-CoV-2 SARS-CoV-2-specific immune response SARS-CoV-2-specific immune responses severe cases single cell RNA sequencing Single-cell RNA sequencing subjects subset sustained T cell T cell activation T cell response T/B cell receptor repertoire. TCR upregulation was increased weakened with COVID-19 zone
[DOI] 10.1016/j.intimp.2022.108767 PMC 바로가기 [Article Type] Article

COVID-19 pharmacotherapy utilization patterns during pregnancy: International Registry of Coronavirus Exposure in Pregnancy

Observational Study

Published on 2022-07-012022-10-04
Journal: Pharmacoepidemiology and drug safety [Category] COVID19(2023년), SARS, 임상,

[키워드] antibody Anticoagulant chloroquine/hydroxychloroquine country COVID-19 COVID-19 patient COVID-19 test COVID-19 therapeutics COVID-19 treatment demographic characteristics drug drug utilization enrolled exposure finding Health include increased risk infected with SARS-CoV-2 information interferon International medications Mild moderate MOST Neonatal Observational cohort study Obstetric online questionnaire oseltamivir outcome outcomes participant pattern pharmacoepidemiology Pregnancy pregnant pregnant women Preterm birth registry Remdesivir reported repurposed therapy risk safety profile severe cases steroid Symptoms Therapies therapy treat with COVID-19 women
[DOI] 10.1002/pds.5440 PMC 바로가기 [Article Type] Observational Study

Cerebrospinal fluid analysis of pregnant women at early stages of COVID-19

Observational Study

Published on 2022-07-012022-10-05
Journal: Taiwanese journal of obstetrics & gynecology [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술,

Saliva changes in composition associated to COVID-19: a preliminary study

COVID-19와 관련된 타액 조성 변화: 예비 연구

Article

Published on 2022-06-272022-09-11
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 임상, 진단, 치료기술, 치료법,

[키워드] Activation ACTN4 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggregation Anosmia antibody ANXA4 Asymptomatic CA6 can be used caused changes in clinical presentation Clinical presentations composed control group coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID 19 COVID-19 COVID-19 group diagnostic diagnostics disease Diseases downregulation dysgeusia FGB FIVE healthy healthy individual immune response involved Mild mild COVID-19 patient mild COVID-19 patients occur oxidative damage pathophysiology Patient patients patients with COVID-19 Perspective positive Potential biomarker potential biomarkers Protective Protein proteome proteomic study proteomics pulmonary tissue quantification respiratory complication Respiratory complications RT-PCR Saliva saliva samples salivary SARS-CoV 2 separated severe acute respiratory syndrome Coronavirus severe cases severe COVID-19 stimulus taste perception tested TGM3 the disease tissue Treatment two groups upregulation variety viral infection virus
[DOI] 10.1038/s41598-022-14830-6 PMC 바로가기 [Article Type] Article

Immunometabolic analysis shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causes

Research article

Published on 2022-06-242022-10-05
Journal: Heliyon [Category] 바이오마커, 치료기술,

[키워드] accompanied Analysis cause CD14+ CD14+ monocyte CD8+ T cells change characteristic Cohort concentrations controls correlated COVID-19 Critical cytokine Cytokine release syndrome Disease progression disease severity expression flow cytometry greater healthy control Hypothesis immune checkpoint immune response immunometabolism involved Lipid mechanism metabolic derangement metabolic risk factor metabolism monocytopenia mononuclear cell multiplex pandemic Pathway analysis Patient PBMC PBMCs PD-L1 Peripheral blood Phosphatidylcholine plasma plasma concentration recruited reduced reflect Result Sepsis serum severe cases severity shown SOFA score Support systemic inflammatory response the disease Treg Tryptophan unique was increased was performed
[DOI] 10.1016/j.heliyon.2022.e09733 [Article Type] Research article

Longitudinal alterations of the gut mycobiota and microbiota on COVID-19 severity

COVID-19 중증도에 따른 장내 세균총 및 미생물총의 종단적 변화

Article

Published on 2022-06-242022-09-11
Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 치료기술,

[키워드] abundance alteration analyzed Bacterial Bacteroides Candida Candida albicans characteristic characterized Community comparable condition correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity decrease discharge Enterococcus Faecalibacterium Follow-up fungal group groups Gut healthy healthy individual in some increase in lactobacillus longitudinal Lower metagenomic sequencing microbial microbiota Mild mild cases mild patients MONITOR Mycobiota Mycobiota. no difference no differences Patient patients with COVID-19 positively correlated remained SARS-COV-2 infection severe cases severe COVID-19 severe group severe patients the healthy
[DOI] 10.1186/s12879-022-07358-7 PMC 바로가기 [Article Type] Article

Pulmonary and Systemic Pathology in COVID-19

Article

Published on 2022-06-242022-11-15
Journal: Deutsches Ärzteblatt international [Category] COVID19(2023년), SARS, 진단, 치료기술,

Age-Dependent Risks of COVID-19 Putatively Caused by Variant Alpha in Japan

일본의 변종 알파에 의한 것으로 추정되는 COVID-19의 연령 의존적 위험

Article

Published on 2022-06-102022-09-11
Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age all age group all age groups Alpha Analysis Assessing Care caused conducted Continuous continuous monitoring coronavirus coronavirus disease COVID-19 COVID-19 case COVID-19 cases death decrease Descriptive analyses Descriptive analysis Diagnosis epidemiological group health center incidence increased risk individual Infection Japan Medical care medical resource Mutation Older Patient patients proportion risk SARS-CoV-2 secure severe acute respiratory syndrome Coronavirus Severe case severe cases severity statistical Statistical estimation strain Strains variant variant of concern with COVID-19
[DOI] 10.3389/fpubh.2022.837970 PMC 바로가기 [Article Type] Article