Protease Activated Receptors: A Pathway to Boosting Mesenchymal Stromal Cell Therapeutic Efficacy in Acute Respiratory Distress Syndrome?Review Published on 2022-01-242022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, [키워드] anticipated benefit boost Cell COVID-19 pandemic critically ill patients Defense develop Efficiency effort endothelial ENhance epithelial expressed G-protein growth Host Infection inflammatory condition Lung injury Mesenchymal stromal cell Mesenchymal stromal cells mortality rate MSC MSCs outcomes pharmacological protease activated receptors receptor respiratory Respiratory failure secretion Sepsis Severe case shown Steroids supportive care survival tested therapeutic Therapeutic benefit therapeutic effect translational [DOI] 10.3390/ijms23031277 PMC 바로가기 [Article Type] Review
Treatment with therapeutic plasma exchange in severe COVID-19 pneumonia: A case report and review of the literatureCase report Published on 2022-01-212022-10-05 Journal: Respiratory Medicine Case Reports [Category] 임상, 치료법, [키워드] Case report clinical evidence Clinical improvement clinical trial complications coronavirus COVID-19 COVID-19 patient Critically ill Deterioration facilitated female Intensive laboratory-confirmed mechanical ventilation outcome parameter Patient patients positive Prevent prevented reduce required severe COVID-19 severe COVID-19 patients supportive care the disease Therapeutic approach therapeutic option Therapeutic plasma exchange therapeutic strategy TPE Treatment worsening [DOI] 10.1016/j.rmcr.2022.101587 [Article Type] Case report
Negative Nasopharyngeal SARS-CoV-2 PCR Conversion in Response to Different Therapeutic InterventionsInfectious Disease Published on 2022-01-202022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accelerate antimalarial antiviral drug association Care Chloroquine clearance Combination conversion Course COVID-19 diagnosis of COVID-19 FIVE HCQ hospital Hydroxychloroquine Infection prevention Infectious disease interquartile range Intervention management median time medication nasopharyngeal negative Negative PCR Novel coronavirus Patient PCR polymerase chain prescribing response Result retrospective cohort study SARS-CoV-2 SARS-CoV-2 PCR Saudi Arabia secondary endpoint shown statistically significant difference supportive care the disease the median therapeutic interventions [DOI] 10.7759/cureus.21442 PMC 바로가기 [Article Type] Infectious Disease
SARS-CoV-2 Infection and Active, Multiorgan, Severe cGVHD After HSCT for Adolescent ALL: More Luck Than Understanding? A Case ReportPediatrics Published on 2022-01-142022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] activating acute respiratory syndrome addition Adolescent anti-SARS-CoV-2 applied autoantibody B cell B-cell Case report CD21 chronic graft vs. host disease clearance of SARS-CoV-2 Combination Complete complex Computed tomography coronavirus cough Course COVID-19 diagnosed disease Donor EBV elevated Evolution expression Extracorporeal photopheresis HSCT humoral immune response ill patient immune immune dysregulation immunodeficiency immunological immunomodulatory Infection infectious complication Laboratory test Loss of Smell Luck lymphopenia Macrophage male mechanism moderate monoclonal antibody Mortality other immunosuppressive agents oxygen saturation parameter Patient Prednisone regimen Remdesivir report resolution of symptoms risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibody severe disease course Standard Stem cell transplantation steroid supportive care syndrome T-cell immunity the patient transaminitis treated Treatment Viraemia virus [DOI] 10.3389/fped.2021.775318 PMC 바로가기 [Article Type] Pediatrics
When stem cells meet COVID-19: recent advances, challenges and future perspectivesReview Published on 2022-01-102022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, SARS, [키워드] acute respiratory distress approaches caused Cell clinically Coronavirus disease 2019 COVID-19 COVID-19 pandemic develop disease effective global public health hypoxic respiratory failure lack Mortality MSCs multiple organ failure Organoid models Perspective provide rate of infection Research Respiratory Coronavirus SARS-CoV-2 stem cell Stem cell therapy Stem cell threapy supportive care syndrome systematic review Therapies Treatment [DOI] 10.1186/s13287-021-02683-1 PMC 바로가기 [Article Type] Review
Kaposi’s Sarcoma-Associated Herpesvirus, but Not Epstein-Barr Virus, Co-infection Associates With Coronavirus Disease 2019 Severity and Outcome in South African PatientsMicrobiology Published on 2022-01-062022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] addition adjusted African age Associate Cape Cohort coronavirus 2 COVID-19 COVID-19 disease severity COVID-19 patient COVID-19 patients COVID-19 severity death detectable died disease DNA EBV Enrollment Epstein-Barr virus herpesvirus HIV HIV positive Human Infection KSHV lytic reactivation median age men Non-communicable disease outcome Oxygen therapy pandemic Patient PCR-confirmed Peripheral blood prevalent respiratory SARS-CoV-2 SARS-COV-2 infection serology seropositive Sex South South Africa supportive care synergy the WHO These data town Tuberculosis viral infection Viral load virus while women [DOI] 10.3389/fmicb.2021.795555 PMC 바로가기 [Article Type] Microbiology
Guillain-Barré Syndrome Associated with SARS CoV-2 Infection: Case ReportCase Report Published on 2022-01-012022-10-31 Journal: Ethiopian Journal of Health Sciences [Category] COVID-19, SARS, [키워드] Analysis Bacterial infections Case report cerebrospinal fluid coronavirus 2 coronavirus disease 19 COVID 19 COVID-19 develop Ethiopian fatigue Guillain Barré syndrome headache improve clinical outcomes Inflammatory limb loss of appetite male management Manifestations Mild motor neurologic neurologic symptoms Neuropathy outbreak Patient positive presentation presenting report respiratory Respiratory failure SARS CoV-2 SARS CoV2 Sensory supportive care treated weakness [DOI] 10.4314/ejhs.v32i1.21 PMC 바로가기 [Article Type] Case Report
A nomogram prediction of outcome in patients with COVID-19 based on individual characteristics incorporating immune response-related indicators면역 반응 관련 지표를 통합한 개인 특성을 기반으로 한 코로나19 환자의 결과에 대한 노모그램 예측Article Published on 2022-01-012022-09-12 Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, [키워드] age albumin Analysis Blood urea nitrogen Characteristics Clinical outcome coronavirus disease COVID-19 COVID-19 patient Disease progression disease severity effective Factor follow-up time high risk identify IgG immune immune response indicated Intensive lactate dehydrogenase Logistic median Monocytes Neutrophil-to-lymphocyte ratio NLR nomogram outcome Patient patients with COVID-19 phenotype Platelet predict prediction predictors procalcitonin Prognosis prognostic progression public health risk severe disease Severe patient severe patients severity of COVID-19 significantly supportive care Therapeutic strategies [DOI] 10.1002/jmv.27275 PMC 바로가기 [Article Type] Article
Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor SilibininPerspective Published on 2021-12-242022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] active cancer acute respiratory distress addition Admission ARDS arising C-reactive protein cascade caused clinical clinical trial Complete COVID-19 COVID-19 illness COVID-GRAM COVID-GRAM score Critical death demonstrated disease dysregulation EudraCT events exhibited high risk hospitalized patient IMPROVE inhibitor intensive care interstitial pneumonia Intervention invasive ventilation knowledge Legalon lymphocytopenia multiorgan failure outcome oxygen support Pathogenesis pathophysiology Patient patients Perspective predicted presenting Proinflammatory response pulmonary lesions receiving recruited required Research SARS-CoV-2 severe COVID-19 Side-effects silibinin STAT3 supportive care syndrome therapy transcriptional treating COVID-19 Treatment [DOI] 10.3390/ph15010019 PMC 바로가기 [Article Type] Perspective
Dark urine as the initial manifestation of COVID-19: a case reportCase Report Published on 2021-12-022022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] Acute kidney injury acute respiratory syndrome Admission Atypical bloodstream Case report complication of COVID-19 component constipation coronavirus coronavirus disease Course COVID-19 creatine kinase creatinine kinase Dark urine defined Dexamethasone discharged Fever hospital hypoxia initial intravenous Liver injury male mechanism Necrosis Patient polymerase chain positive reported required Research rhabdomyolysis SARS-CoV-2 supplemental oxygen supportive care symptomatic syndrome the patient therapy Topic Treatment Urine [DOI] 10.1186/s13256-021-03173-x PMC 바로가기 [Article Type] Case Report