Combination of (interferon beta-1b, lopinavir/ritonavir and ribavirin) versus favipiravir in hospitalized patients with non-critical COVID-19: A cohort study비 임계 CovID-19를 가진 입원 환자에서 (인터페론 베타 -1B, 로피 나비르/리토 나비르 및 리바비린) 대 Favipiravir의 조합 : 코호트 연구Comparative Study Published on 2021-06-102022-09-10 Journal: PLoS ONE [Category] SARS, 치료제, [키워드] (Lopinavir/ritonavir 28-day mortality adjusted hazard ratio allocation antiviral therapy association change Cohort cohort study confounders Corticosteroids covariate COVID-19 Cox regression model diarrhea disease severity Efficacy and safety examined Favipiravir FPV groups Hospitalization hospitalized COVID-19 patients hospitalized patient hospitalized patients IFN interferon Interferon beta-1b less Lopinavir Lopinavir/ritonavir median Mortality National national treatment nausea objective observational study patients required Result ribavirin Ritonavir study cohort symptoms onset systemic corticosteroid systemic corticosteroids therapy treated Treatment treatment group Treatment protocol [DOI] 10.1371/journal.pone.0252984 PMC 바로가기 [Article Type] Comparative Study
High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin AmericaCOVID-19 또는 다기관 염증 증후군 아동의 높은 항생제 처방률: 라틴 아메리카에서 990건의 다국적 경험Article Published on 2021-06-012022-09-11 Journal: Acta paediatrica (Oslo, Norway : 1992) [Category] SARS, 치료기술, [키워드] administration antibiotic antibiotic use Antibiotics ARDS Bacterial infection Bacterial infections Care chest X-ray chest X-rays children children with COVID-19 Corticosteroids country COVID-19 CPAP determinant diagnosis of COVID-19 enrolled Evidence Factor female FIVE hospital hospital care hospitals Inflammatory intensive care Latin America management mechanical ventilation MIS-C oxygen oxygen support Pneumonia Prevalence Prospective Pyrexia Recognition SARS-CoV-2 severe disease Sex stewardship. systemic corticosteroid systemic corticosteroids use of antibiotics Variation were assessed with COVID-19 [DOI] 10.1111/apa.15847 PMC 바로가기 [Article Type] Article
Corticosteroids for hospitalized patients with mild to critically-ill COVID-19: a multicenter, retrospective, propensity score-matched studyClinical Trial Published on 2021-05-212022-10-04 Journal: Scientific Reports [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval administration analyzed assigned baseline clinical clinical microbiology clinical status coronavirus disease Corticosteroid Corticosteroids COVID-19 COVID-19 patient Day diagnosed disease disease severity Efficacy enrolled evaluate Factor hazard ratio hospital hospitalized COVID-19 patient hospitalized patient IMPROVE intubation Invasive mechanical ventilation Japan Methylprednisolone Mild multicenter network Odds ratio outcome Patient primary endpoint propensity score matching radiological finding receive reduced Registered registry required retrospective Retrospective study Severe patient severity significantly lower significantly shorter Standard dose systemic corticosteroid university use of corticosteroid Ventilation Virology with COVID-19 [DOI] 10.1038/s41598-021-90246-y PMC 바로가기 [Article Type] Clinical Trial
Management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline코로나바이러스 질환 2019(COVID-19)로 입원한 성인 관리: 유럽 호흡기 학회 생활 지침Practice Guideline Published on 2021-04-152022-09-11 Journal: The European Respiratory Journal [Category] Fulltext, MERS, meta-analysis, [키워드] anticoagulation approach Azithromycin Care Chinese Colchicine Continuous Positive Airway Pressure coronavirus disease Coronavirus disease 2019 Corticosteroids COVID-19 European Evidence high mortality rate High-flow nasal oxygen hospitalised Hospitalised patients Hydroxychloroquine hypoxaemic respiratory failure IMPROVE initial interleukin Intervention Invasive mechanical ventilation invasive ventilation literature review Lopinavir Lopinavir-ritonavir management Meta-analysis monoclonal antibody treatment noninvasive respiratory Optimising outcome outcomes oxygen Patient performed pharmacological PICO positive airway pressure receptor receptor antagonist recommendation recommendations Remdesivir requiring supplemental oxygen Research respiratory Respiratory failure Ritonavir SARS-COV-2 infection Society strength supplemental oxygen supplementary oxygen Support systemic corticosteroid systemic corticosteroids Task Force use of hydroxychloroquine ventilatory support was used were used [DOI] 10.1183/13993003.00048-2021 PMC 바로가기 [Article Type] Practice Guideline
Pityriasis rosea Gibert triggered by SARS-CoV-2 infection A case report4900 Published on 2021-04-092022-10-30 Journal: Medicine [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Adults association Case report coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Department Diagnosis epidemiological etiology Evolution extension female hydrocortisone hemisuccinate Infection infections initiated lesion lower limb medication nasal occur pandemic Patient performed Pharyngeal swab pityriasis rosea pityriasis rosea Gibert positive RT-PCR pruritus Rash reported respiratory tract infection RT-PCR SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 skin lesion Spread systemic corticosteroid the patient the SARS-CoV-2 therapy Treatment triggered upper limbs upper respiratory tract [DOI] 10.1097/MD.0000000000025352 PMC 바로가기 [Article Type] 4900
Combination therapy with tocilizumab and corticosteroids for aged patients with severe COVID-19 pneumonia: A single-center retrospective study중증 COVID-19 폐렴이 있는 고령 환자에 대한 토실리주맙 및 코르티코스테로이드 병용 요법: 단일 센터 후향적 연구Article Published on 2021-04-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] 28-day mortality 95% confidence interval all-cause mortality Analysis applied both groups clinical Clinical improvement Combination conducted consecutive patient Corticosteroid Corticosteroids COVID-19 Cytokine release syndrome decrease discharge dose doses groups hazard ratio immunomodulation immunomodulatory therapy Infection intravenous tocilizumab Methylprednisolone Mortality Occurrence Odds ratio outcome Patient Primary outcome Probability Propensity score protective effect retrospective Retrospective study SARS-CoV-2 secondary outcome severe COVID-19 single-center single-center study systemic corticosteroid TCZ therapy Tocilizumab Total treated Treatment [DOI] 10.1016/j.ijid.2021.02.099 PMC 바로가기 [Article Type] Article
Judicious use of low-dosage corticosteroids for non-severe COVID-19: A case reportCase Report Published on 2021-03-192022-10-28 Journal: Open Medicine [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome Administered administration of corticosteroid antiviral drugs ARDS attenuate Case report chest CT scan China complete recovery Coronavirus disease 2019 Corticosteroid corticosteroid therapy COVID-19 COVID-19 case COVID-19 disease critical COVID-19 patient Cytokine storm death Disease progression dosage Efficacy Evidence facilitated immunosuppressive infection with SARS-CoV-2 Inflammatory lack lung Lung inflammation Lung injury Methylprednisolone Personalized medicine progression reduction in Regular Respiratory failure retrospective Safe SARS-CoV-2 Severe case supportive care syndrome systemic corticosteroid Therapeutic approach therapy Treatment use of corticosteroid was recorded WHO [DOI] 10.1515/med-2021-0250 PMC 바로가기 [Article Type] Case Report
Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi methodResearch Published on 2021-03-162022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] acute respiratory distress agreement ARDS blocking agent caused Chi-square clinical Clinical practice clinically Consensus Coronavirus disease 2019 COVID 19 invasive mechanical ventilation COVID-19 COVID-19 acute respiratory distress syndrome COVID-19 high flow nasal oxygen COVID-19 respiratory management COVID-19 ventilatory management Critical defined DelPhi Delphi method develop Evidence expert expiratory form Healthcare system hemodynamic instability IMPROVE International intubation Likert scale lung management nasal oxygen Non-COVID-19 patients non-invasive ventilation Oxygenation pandemic Patient per day Personal protective equipment positive Prone ventilation Protective reached reduce Registered Respiratory distress syndrome adult Respiratory failure Result risk suction supplementary material syndrome systemic corticosteroid tracheal Variation [DOI] 10.1186/s13054-021-03491-y PMC 바로가기 [Article Type] Research
Impact of previous exposure to systemic corticosteroids on unfavorable outcome in patients hospitalized for COVID-19Research Article Published on 2021-03-112022-10-28 Journal: BMC Pharmacology & Toxicology [Category] COVID-19, [키워드] 95% CIs 95% confidence interval absence adjusted Admission age calculated chronic Cohort Comorbidities Comorbidity Corticosteroid COVID-19 COVID-19 severity death Evidence exposure to France hospital Hospital admission hospitalized patient Impact increased risk inflammatory disease intensive care intensive care unit mechanical ventilation men Mortality Odds ratio outcome overlap Patient patients hospitalized pharmacoepidemiology polymerase chain positive Primary outcome provided question radiological Regression model Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia supplementary material systemic corticosteroid systemic corticosteroids transcriptase university variable Weighting [DOI] 10.1186/s40360-021-00480-3 PMC 바로가기 [Article Type] Research Article
Characteristics and outcomes in hospitalized COVID-19 patients during the first 28 days of the spring and autumn pandemic waves in Milan: An observational prospective study밀라노의 봄과 가을 유행성 파도의 첫 28일 동안 입원한 COVID-19 환자의 특성 및 결과: 관찰 전향 연구Observational Study Published on 2021-03-012022-09-11 Journal: Respiratory medicine [Category] 임상, 치료제, [키워드] Administered Adult patients anticoagulation Changing Characteristics Clinical studies comparable Corticosteroid Corticosteroids COVID-19 COVID-19 patients COVID-19 pneumonia CPAP D-dimer Dexamethasone discharged home distress Effect enoxaparin FEU Healthcare system Hospital mortality Hospital stay hospitalized COVID-19 patient hospitalized COVID-19 patients Hydroxychloroquine in-hospital mortality initiated International intubation Italy Lopinavir Lopinavir/ritonavir males material Methylprednisolone Mortality observational study outcome oxygen oxygen mask oxygen masks pandemic Patient patients hospitalized Pneumonia proportion Prospective Study recommendations reduced regimen Remdesivir respiratory respiratory distress Respiratory failure Ritonavir severe pneumonia severe respiratory failure systemic corticosteroid systemic corticosteroids therapeutic Therapeutic approach Thromboprophylaxis thrombosis Treatment were given with COVID-19 [DOI] 10.1016/j.rmed.2021.106323 PMC 바로가기 [Article Type] Observational Study