Cold atmospheric plasma: A non-negligible strategy for viral RNA inactivation to prevent SARS-CoV-2 environmental transmissionRegular Articles Published on 2021-08-102022-10-28 Journal: AIP Advances [Category] COVID-19, [키워드] acute respiratory syndrome Analysis antiviral properties applied atmospheric carried cell membrane Cold coronavirus decrease dose Effect ELISA emission spectra experiment Express fluorescent inactivation indicated Infection mechanism membrane molecular weight optical plasma polyacrylamide gel Prevent Protein pseudovirus qPCR Receptor binding domain SARS-CoV-2 significantly sodium Spike protein TEM Transmission transmission electron microscopy Viral RNA [DOI] 10.1063/5.0060530 PMC 바로가기 [Article Type] Regular Articles
Secretory Vesicles Are the Principal Means of SARS-CoV-2 EgressArticle Published on 2021-08-102022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition analysed Antiviral strategies biosynthetic Cell cellular compartment coronavirus Coronaviruses COVID-19 extracellular space HIV Hypothesis immunodeficiency in viral infected with SARS-CoV-2 late stage lysosome macrophages mechanism Microscope other coronaviruses Particle plasma membrane principal released SARS-CoV-2 secretory secretory pathway serial sections suggested TEM the SARS-CoV-2 thought transmission electron microscopy Vero Cell Vesicle vesicles virus virus egress virus release [DOI] 10.3390/cells10082047 PMC 바로가기 [Article Type] Article
Adventitial Microcirculation Is a Major Target of SARS-CoV-2-Mediated Vascular InflammationCase Report Published on 2021-07-202022-10-28 Journal: Biomolecules [Category] COVID-19, SARS, [키워드] ACE2 receptor affected alteration analyses Analysis artery disease cardiovascular complication Case report changes controls coronavirus Coronavirus disease-19 Course COVID-19 cytoplasm disease Endothelial cell endothelial injury expressed functional histological IHC IL-6 immunohistochemistry infected with SARS-CoV-2 Infection Inflammation Inflammatory lower limb Major mechanism media Microcirculation miRNA mRNA occlusive oedema popliteal Protein SARS-CoV-2 significantly increased staining target TEM transmission electron microscopy Vascular damage was reduced [DOI] 10.3390/biom11071063 PMC 바로가기 [Article Type] Case Report
Copper-Silver Nanohybrids: SARS-CoV-2 Inhibitory SurfacesArticle Published on 2021-07-132022-10-30 Journal: Nanomaterials [Category] COVID-19, [키워드] acute respiratory syndrome antiviral property characterized copper coronavirus COVID-19 infection Efficacy example Health hospital Human human-animal interfaces inhibited inhibitory inhibitory surfaces lesson Microscope Microscopy nanohybrids pandemic parameter reveal SARS-CoV-2 SEM silver surface TEM the SARS-CoV-2 Toxicity Transmission X-ray spectroscopy [DOI] 10.3390/nano11071820 PMC 바로가기 [Article Type] Article
Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic ProfilingArticle Published on 2021-07-062022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] AAK1 ADP AgNP AgNPs Analysis anti-SARS-CoV-2 Antiviral antiviral activity AutoDock biosynthesized carried cathepsin caused Compound conducted COVID-19 demonstrated docking study drug candidate evaluated fatty acids FIVE Fragaria ginger globe Health high stability High-resolution highest Human in silico In silico modeling indicate inhibitor inhibitory Interaction life-threatening metabolic metabolomic profiling Microscope modeling molecular molecular docking MPro MTT nanoparticle Nanoparticles Novel coronavirus overcome pandemic phosphatase PLPro Pneumonia Potential predict Profiling Protein Proteins provide responsible SARS-CoV-2 SARS-CoV-2 protein Secondary Metabolite Seven silver spectrophotometric analysis strawberry target TEM the SARS-CoV-2 Transmission Viral protein was performed were used zeta potential Zingiber [DOI] 10.3390/antibiotics10070824 PMC 바로가기 [Article Type] Article
Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2헤스페리딘에 의해 매개되는 항바이러스성 산화아연 나노입자와 항-SARS-CoV-2로서의 항바이러스성 페놀계 물질 간의 in silico 비교 연구Article Published on 2021-07-012022-09-11 Journal: Colloids and surfaces. B, Biointerfaces [Category] SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Analysis anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity Antiviral antiviral activity antiviral agent Antiviral agents assist caused characterized complementary Compound coronavirus COVID-19 curative death docking score evaluated example HAV Hepatitis hepatitis A hepatitis A virus hesperidin highest in silico Infection Isolation leads measure metabolite molecular docking nutraceutical nutraceuticals pandemic pharmaceutical Potential treatment predicted protocol protocols reducing reducing agent required respiratory responsible RNA viruses Safe SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Side effects synthesis TEM tested Treatment virus Zinc zinc oxide zinc oxide nanoparticles [DOI] 10.1016/j.colsurfb.2021.111724 PMC 바로가기 [Article Type] Article
Sub-3 Å Cryo-EM Structures of Necrosis Virus Particles via the Use of Multipurpose TEM with Electron Counting CameraArticle Published on 2021-06-252022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, MERS, SARS, [키워드] Arctica atomic camera capsids counting COVID-19 cryo-EM cryo-EM structure de novo demonstrated direct electron camera electron global pandemic globe High-resolution icosahedral particles Infectious virus investigated Macrobrachium rosenbergii Microscope Necrosis nodavirus Pandemics Particle Particles Proteins regulated Research single particle Structure TEM tested virus [DOI] 10.3390/ijms22136859 PMC 바로가기 [Article Type] Article
Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVsTechnical Report Published on 2021-06-032022-10-29 Journal: Journal of Extracellular Vesicles [Category] COVID-19, MERS, [키워드] Analysis Biomarker capture cellular circulating circulating miRNAs Cohort convalescent sera Critical current demonstrated disease severity downregulated EVs exosome purification extracellular vesicle Extracellular vesicles highlight Hospitalized Human plasma IgG titers in vitro Isolation micro‐RNA profiling miRNA biomarker Neutralizing nucleic acids Patient patients physical purification Release SARS‐CoV‐2 selective sensitivity Sequencing sequencing data significantly subset TEM tissues transmission electron microscopy were used western blotting whole serum [DOI] 10.1002/jev2.12110 PMC 바로가기 [Article Type] Technical Report
Carbapenem-Resistant Klebsiella pneumoniae Infections in ICU COVID-19 Patients—A Scoping ReviewReview Published on 2021-05-122022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age analyzed Antibiotic therapy Antibiotics applied Bacteria Bacterial carbapenem carbapenem-resistance caused change Cochrane Library Community conducted contribute Course COVID-19 CTX-M database drug exclusion criteria exhibiting hospital ICU Immunocompromised patient infected patient Infection infections isolates Klebsiella pneumoniae KPC literature review majority male multidrug-resistant NDM New coronavirus new SARS-CoV-2 Organisms pandemic pathogen Patient patients hospitalized patients with COVID-19 predominant Prevalence Prevent PROTECT protocol ranged recommendations review searched Spread Surveillance TEM [DOI] 10.3390/jcm10102067 PMC 바로가기 [Article Type] Review
COVID-19 Associated Hypercoagulability: Manifestations, Mechanisms, and ManagementArticle Published on 2021-04-022023-06-16 Journal: Shock (Augusta, Ga.) [Category] MERS, [키워드] a disintegrin and metalloproteinase with thrombospondin type 1 motif member 13 ADAMTS13 CFT clot formation time Coagulation coronavirus coronavirus disease-2019 COVID-19 ECMO Embolism extracorporeal membrane oxygenation ICU IL intensive care unit interleukin Jak Janus kinase k kinetic time MA MAPK maximum amplitude maximum clot firmness MCF mitogen-activated protein kinase PAI-1 PGI2 Plasminogen activator inhibitor-1 prostacyclin SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 TEG TEM thromboelastography Thromboelastometry thrombosis TNF tumor necrosis factor ultra-large von Willebrand factor ULVWF Venous Thromboembolism VTE [DOI] 10.1097/SHK.0000000000001660 PMC 바로가기