Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance studyOriginal Research Published on 2022-05-102024-09-04 Journal: Therapeutic Advances in Gastroenterology [Category] 대상포진, [키워드] steroid-free Tofacitinib ulcerative colitis [DOI] 10.1177/17562848221090834 PMC 바로가기 [Article Type] Original Research
The Comparative Risk of Serious Adverse Events With Tofacitinib and TNF Inhibitors in Patients With Ulcerative Colitis: The Korean Experience as Revealed by a National DatabaseBrief Communication Published on 2022-04-122024-09-04 Journal: Journal of Korean medical science [Category] 대상포진, [키워드] Side effect Tofacitinib ulcerative colitis [DOI] 10.3346/jkms.2022.37.e123 PMC 바로가기 [Article Type] Brief Communication
JAK inhibitors and COVID-19JAK 억제제 및 COVID-19Review Published on 2022-04-012022-09-11 Journal: Journal for immunotherapy of cancer [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] activated added Antiviral antiviral molecules Autoimmunity Baricitinib benefit clinical experience clinical trials coded concerning contributing to COVID-19 COVID-19 treatment cut-off cytokine Cytokine storm Cytokines differentiation Effect Effects Evolution family Graft hematologic hematologic neoplasms Human genome immune regulation immune response Immunosuppression immunosuppressive effect immunosuppressive effects indicated induce inhibited innate immune response interferons involved issue Jak JAK inhibitor jak inhibitors JAK1 JAK2 JAK3 JAKi janus Janus kinase kinases Meta-analysis moment Neoplasms nezulcitinib outcome pathogenic pathway Pathways patients treated patients with COVID-19 Phase 3 trials proliferation randomized clinical trial RCT reaction receptor reduce mortality rheumatic disease Rheumatic diseases risk reduction ruxolitinib SARS-COV-2 infection severe COVID-19 Side effect Signaling Significant Standard of care subsequent suggested survival the SARS-CoV-2 the WHO Therapies therapies, investigational. Tofacitinib transmembrane Treatment trials TYK2 Type I IFN type I interferons Viral viral replication virus clearance [DOI] 10.1136/jitc-2021-002838 PMC 바로가기 [Article Type] Review
Pharmacological treatment of COVID-19: an opinion paperCOVID-19의 약리학적 치료: 의견서Review Published on 2022-04-012022-09-11 Journal: Revista española de quimioterapia : publicación [Category] COVID19(2023년), SARS, 치료제, [키워드] adalimumab Anakinra approach AZD7442 Azithromycin Banlanivimab Baricitinib BRII-196 BRII-198 canakinumab Casirivimab Certolizumab Ciganilmab Colchicine college Committee convalescent convalescent plasma COVID-19 Critical Dexamethasone drug drugs effective Efficacy English Etanercept etesevimab Evusheld Favipiravir fluvoxamine Golimumab help Hydroxychloroquine Imdevinab immune response Immunotherapy indication infliximab itolizumab Ivermectin Lemilumab Lopinavir Lopinavir/ritonavir Medicines metformin molnupiravir offer Pandemia pandemic Paxlovid PF-07321332 physician precocity prevented Ravulizumab Remdesivir Ritonavir ruxolitinib sarilumab SARS-CoV-2 Scientific Committee Sotrovimab Spanish the vaccine therapeutic Tixagevimab Tocilizumab Tofacitinib Treatment Vaccine virus Vitamin Vitamin D [DOI] 10.37201/req/158.2021 PMC 바로가기 [Article Type] Review
Management of hepatitis B virus reactivation due to treatment of COVID-19코로나19 치료로 인한 B형 간염 바이러스 재활성화 관리Review Published on 2022-04-012022-09-11 Journal: Hepatology international [Category] B형 간염, 치료제, [키워드] Antiviral Baricitinib Corticosteroids COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients current dysregulated Evidence Future HBV HBV infection Hepatitis hepatitis B Hepatitis B virus High-dose Immunosuppression immunosuppressive immunosuppressive therapies immunosuppressive therapy increased risk Infection Inflammatory response inhibitor inhibitors janus Janus kinase Liver function test Liver injury management monoclonal antibody other diseases pandemic Patient potentially life-threatening Prophylaxis Reactivation receiving risk sarilumab SARS-CoV-2 severe disease the patient Therapies Tocilizumab Tofacitinib Treatment treatments for COVID-19 treatments of COVID-19 [DOI] 10.1007/s12072-022-10306-x PMC 바로가기 [Article Type] Review
Tofacitinib and risk of cardiovascular outcomes: results from the Safety of TofAcitinib in Routine care patients with Rheumatoid Arthritis (STAR-RA) studyArticle Published on 2022-03-312024-09-04 Journal: Annals of the rheumatic diseases [Category] 대상포진, [키워드] Cardiovascular outcomes rheumatoid arthritis Tofacitinib [DOI] 10.1136/annrheumdis-2021-221915 PMC 바로가기 [Article Type] Article
Comparative effectiveness of second-line biological therapies for ulcerative colitis and Crohn’s disease in patients with prior failure of anti-tumour necrosis factor treatmentarticle Published on 2022-03-272024-09-02 Journal: BMC Gastroenterology [Category] 대상포진, [키워드] anti-TNF therapy Crohn’s disease Tofacitinib ulcerative colitis ustekinumab vedolizumab [DOI] 10.1186/s12876-022-02225-w PMC 바로가기 [Article Type] article
Initial experience of tofacitinib for treating refractory moderate-to-severe ulcerative colitisCase Report Published on 2022-02-012024-09-04 Journal: Nagoya journal of medical science [Category] 대상포진, [키워드] case reports refractory Tofacitinib ulcerative colitis [DOI] 10.18999/nagjms.84.1.169 PMC 바로가기 [Article Type] Case Report
The Efficacy and Safety of Janus Kinase Inhibitors for Patients With COVID-19: A Living Systematic Review and Meta-AnalysisMedicine Published on 2022-01-272022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI adverse events adverse outcomes Analysis Baricitinib baseline Clinical outcome contribute COVID-19 database decrease decreased mortality demonstrated Efficacy and safety eligible evaluated Evidence Hospitalized hospitalized patient incidence increased mortality JAK inhibitor jak inhibitors janus Janus kinase Janus kinase inhibitors kinase Meta-analysis Mortality no increase observational study outcome Patient patients with COVID-19 Randomized controlled trial RCTs Registration required Result retrieved review risk ruxolitinib Safety SARS-CoV-2 searched significant decrease significantly subgroup analysis supplemental oxygen systematic review the cytokine storm Tofacitinib Treatment Ventilation with COVID-19 [DOI] 10.3389/fmed.2021.800492 PMC 바로가기 [Article Type] Medicine
Tofacitinib for Biologic-Experienced Hospitalized Patients with Acute Severe Ulcerative Colitis: A Retrospective Case-Control StudyArticle Published on 2022-01-082024-09-04 Journal: Clinical gastroenterology and hepatology : the off [Category] 대상포진, [키워드] colectomy Tofacitinib ulcerative colitis [DOI] 10.1016/j.cgh.2021.05.038 PMC 바로가기 [Article Type] Article