Low-entry-barrier point-of-care testing of anti-SARS-CoV-2 IgG in the population of Upper Austria from December 2020 until April 2021—a feasible surveillance strategy for post-pandemic monitoring?2020 년 12 월부터 2021 년 4 월까지 오스트리아 어퍼 오스트리아 인구에서 항 -SARS-COV-2 IGG의 저지전 배리어 요약 테스트-밴혈 후 모니터링을위한 실행 가능한 감시 전략?Research Paper Published on 2022-02-282022-09-08 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, 치료기술, [키워드] Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyses Analysis analyzed anonymized data anti-SARS-CoV-2 IgG antibody antibody levels Antigen approach continuous monitoring coronavirus COVID-19 COVID-19 pandemic defined diagnostic diagnostic testing estimate feasible IgG antibodies IgG antibody immune Immune status Immunoglobulin Immunoglobulin G Infection International limit Local National PCR Peripheral blood Pharmacy point-of-care Population populations Prevalence Rapid test Region reported respiratory SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens Seroprevalence severe acute respiratory syndrome Coronavirus Spread Surveillance upper vaccinated individuals Volunteer volunteers [DOI] 10.1007/s00216-022-03966-z PMC 바로가기 [Article Type] Research Paper
Limited Recognition of Highly Conserved Regions of SARS-CoV-2SARS-CoV-2의 고도로 보존된 지역에 대한 제한된 인식Research Article Published on 2022-02-232022-09-10 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antigen-specific CD8+ T cells approach CD8 circulating Community Comparative conservation conserved conserved regions convalescent coronavirus coronavirus disease coronavirus strains COVID-19 Critical cross-protective immunity cross-reactive disease encoded protein epitope epitope mapping Epitopes exposure to FIVE Frame generate immune protection immune response immune responses immunodominant implication individuals less likelihood Limited memory memory T cells nucleocapsid observation Open reading frame ORF1 ORF1ab overcome pandemic Participants polyprotein Preexisting immunity protective role Protein Recognition Region required respiratory robust SARS-CoV-2 SARS-CoV-2 infected cells seasonal coronaviruses Sequence analysis severe acute respiratory syndrome Coronavirus severe COVID-19 severe disease T cell T cell response T cell responses T cells T-cell epitope T-cell epitopes T-cell Response T-cell responses understanding unlikely vaccination volunteers [DOI] 10.1128/spectrum.02780-21 PMC 바로가기 [Article Type] Research Article
First responder systems can stay operational under pandemic conditions: results of a European survey during the COVID-19 pandemicOriginal Research Published on 2022-02-192022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] addition affected Algorithm approach Cardiac arrest caused Citizen first responder Community first responder conducted country COVID-19 COVID-19 outbreak COVID-19 pandemic decrease Europe European exhibited First responder identify incidence investigated majority management measure Mortality OHCA outbreak outcome pandemic Patient Personal protective equipment PPE PROTECT questionnaire reported required Responder responders response Result Resuscitation risk second wave shown supplementary material survey survival volunteers [DOI] 10.1186/s13049-022-00998-3 PMC 바로가기 [Article Type] Original Research
Investigation of discordant SARS-CoV-2 RT-PCR results using minimally processed salivaArticle Published on 2022-02-182022-10-04 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome Bioanalytical chemistry Confirmed coronavirus coronavirus disease COVID-19 COVID-19 infection detect Dilution false negative result false negative results Genome healthy heat-inactivated heterogeneous highlight Improvements investigation negative sample positive processed Saliva SARS-CoV-2 RT-PCR significantly viral infection Viral RNA volunteers [DOI] 10.1038/s41598-022-06642-5 PMC 바로가기 [Article Type] Article
Performance evaluation of an automatic chemiluminescence immune platform for SARS-CoV-2 neutralizing antibody after vaccination in real worldSARS-COV-2를위한 자동 화학 발광 면역 플랫폼의 성능 평가 현실에서 예방 접종 후 항체Research Published on 2022-02-152022-09-01 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] Adolescent BBIBP-CorV changes in Characteristics chemiluminescence China CLIA Cohort CoronaVac doses evaluated exceeded Follow-up followed by Hemolysis high correlation icterus immune immunity after vaccination immunoassays inactive injection inoculation investigated less linearity lipemia measure Neutralizing activity Neutralizing antibodies neutralizing antibody objective occurred performance Physical examination Plaque reduction neutralization test platform predominant PRNT Real world recipient recruited repeatability Result robust SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine schedule Sensitivity and specificity Serological assay serological assays seropositive Shenzhen significantly lower Sinovac strength Trial vaccination Vaccination Status Vaccinations Vaccine Variation volunteers [DOI] 10.1186/s12879-022-07141-8 PMC 바로가기 [Article Type] Research
Multiplexed Lab-on-a-Chip Bioassays for Testing Antibodies against SARS-CoV-2 and Its Variants in Multiple Individuals여러 개인의 SARS-CoV-2 및 그 변이체에 대한 항체 테스트를 위한 다중 랩온어칩 바이오어세이Article Published on 2022-02-082022-09-11 Journal: Analytical Chemistry [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody bioassay Concentration coronavirus D614G dose E484K effective ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay exhibit individual L452R less limit of detection Multiple N501Y neutralization assays neutralization test neutralizing activities Neutralizing activity Neutralizing antibodies neutralizing antibody performed plaque reduction neutralization Plaque reduction neutralization test PRNT RBD reagent reagents respiratory SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus target Testing testing antibody throughput Vaccine variants volunteers [DOI] 10.1021/acs.analchem.1c04383 PMC 바로가기 [Article Type] Article
Why Physical Activity Should Be Considered in Clinical Trials for COVID-19 Vaccines: A Focus on Risk GroupsReview Published on 2022-02-072022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Accuracy Activation activity antibodies approved Candidates carried cells clinical clinical questionnaire clinical trial clinical trials concerning COVID-19 COVID-19 vaccine Cytokines Efficacy Evidence focus group immune response immunological tests IMPROVE include obese parameter physical activity question SARS-CoV-2 vaccination Vaccine vaccine candidate vaccine candidates volunteers World Health Organization [DOI] 10.3390/ijerph19031853 PMC 바로가기 [Article Type] Review
Inferring global-scale temporal latent topics from news reports to predict public health interventions for COVID-19Research article Published on 2022-02-012022-10-05 Journal: Patterns [Category] 치료기술, [키워드] Algorithm approach automated categories country COVID-19 COVID-19 pandemic Diseases Effectiveness effort Epidemics Evidence global pandemic improvement Interpretation Intervention latent topic models non-pharmacological interventions NPI NPIs predict Public health intervention public health surveillance Support Topic transfer learning Variational autoencoder volunteers [DOI] 10.1016/j.patter.2022.100435 [Article Type] Research article
Development of an in-house SARS-CoV-2 interferon-gamma ELISpot and plate reader-free spot detection method자체 SARS-CoV-2 인터페론 감마 ELISpot 및 플레이트 리더 프리 스팟 검출 방법 개발Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Antigen antigens automated Concentration convalescent coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 pandemic demonstrated detect development diagnostic effective elicited ELISPOT enzyme enzyme-linked immunospot IFN-γ Immunity Infection Interferon-gamma mononuclear cell mononuclear cells multiple antigen Neutralising Antibodies peptide Peripheral blood Peripheral blood mononuclear cells plate reader quantified reliability Research respiratory response SARS-CoV-2 SARS-CoV-2-specific T cells severe acute respiratory syndrome Coronavirus stimulate T cell T cell response T cell responses T cells vaccination Volunteer volunteers [DOI] 10.1016/j.jviromet.2021.114398 PMC 바로가기 [Article Type] Article
Efficacy and safety profile of COVID-19 vaccine in cancer patients: a prospective, multicenter cohort study암 환자에 대한 COVID-19 백신의 효능 및 안전성 프로파일: 전향적, 다기관 코호트 연구Multicenter Study Published on 2022-01-272022-09-12 Journal: Future Oncology [Category] MERS, SARS, 진단, [키워드] affecting antibody Blood blood sample Cancer cancer patient Cancer patients cancer treatment Chemotherapy Control control group CoronaVac COVID-19 COVID-19 vaccine COVID-19 vaccines defined disease disrupting dose effective Efficacy and safety evaluate evaluated Factor high risk highlight IgG IgG antibody immune response Immunotherapy inactivated Inactivated vaccine inactive infection with SARS-CoV-2 levels of antibodies malignancy marker multicenter cohort study Older Patient PROTECT receiving safety profile SARS-CoV-2 SARS-CoV-2 vaccination seropositive significantly lower spike the patient the vaccine vaccination Vaccine virus volunteers were measured [DOI] 10.2217/fon-2021-1248 PMC 바로가기 [Article Type] Multicenter Study